year 18, Issue 70 (5-2019)                   J. Med. Plants 2019, 18(70): 110-121 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sattarzad Fathi S, Hassanian-Moghaddam H, Shadnia S, Zamani N, Rahimi M. Epidemiological Survey of Poisoning by Plants and Mushrooms in Loghman–e- Hakim Hospital of Tehran, Iran, 2007 – 2013. J. Med. Plants 2019; 18 (70) :110-121
URL: http://jmp.ir/article-1-2567-en.html
1- School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2- Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Department of Clinical Toxicology, Loghman Hakim Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran , mrahimi744@gmail.com
Abstract:   (3612 Views)
Background: Because in today's societies, not only the nutritional role of plants and fungi is very high, but also the main basis of many drugs are plants and plant products, therefore one of the problems of clinical toxicologists is the toxicity of these products.
Objective: This study aimed to define the prevalence, symptoms, complications, effective treatments, type of substance use, the cause of intake, location, gender distribution and age of poisoning with herbs and mushrooms in hospitalized patients of Loghman Hakim Hospital in Tehran.
Methods: This is a retrospective study with questionnaire formulation. Patients reviewed from the beginning of 2007 to the end of 2013.
Results: of 103 cases of poisoning with plants and mushrooms 64.1% were male, and 35.9% were female. The mean age of patients was 21.59 ± 30.51 years. The most commonly used substance is Datura (34%). On the other hand, sole mushroom ingestion was found in 5.8% of cases. The most significant source of plants and mushrooms was reported from herbal-shops (27.18%). The reason behind intake was either random or euphoria. Four patients were admitted to the intensive care unit, and three patients needed intubation. The mean hospital stay was 1.64 ± 1.28 days. Ninety percent of the treatments were supportive, and 75.7% of the patients recovered without any clinical complications.
Conclusion: Poisoning with toxic plants and mushrooms is one of the frequent causes of intoxication that is often accidental. In children poisoning is inadvertent, but youth are more likely wanted to have euphoria. Treatment strategies are supportive and symptomatic.
Full-Text [PDF 1146 kb]   (1324 Downloads)    
Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2018/02/26 | Accepted: 2018/05/29 | Published: 2019/05/26

References
1. Bates BA and Burns MM. Potentially toxic plant ingestions in children: Clinical manifestations and evaluation. 2018 UpToDate.
2. Wiegand TJ, DABAM F and Traub SJ. Clinical manifestations and evaluation of mushroom poisoning. UpToDate, July. 2013, 15.
3. Amini M, Khosrojerdi H and Afshari R. Acute Datura Stramonium poisoning in East of Iran - a case series. Avicenna J. Phytomedicine 2012; 2 (2): 86 - 9.
4. Pietsch J, Koch I, Hermanns-Clausen M, Hüller G, Wagner R and Dressler J. Pediatric plant exposures in Germany, 1998-2004. Clin. Toxicol. 2008 Jan 20; 46 (7): 686 - 91. [DOI:10.1080/15563650701474081]
5. Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, Gossweiler B and Meier-Abt PJ. Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center. Schweiz Med Wochenschr. 1996; 126 (25): 1085 - 98.
6. Krenzelok EP and Mrvos R. Friends and foes in the plant world: a profile of plant ingestions and fatalities. Clin. Toxicol. 2011; 49 (3): 142 - 9. [DOI:10.3109/15563650.2011.568945]
7. Chang S, Wu M, Deng J, toxicology CL-… and human, 1999 undefined. Poisoning by Datura leaves used as edible wild vegetables. researchgate.net. Chang SS, Wu ML, Deng JF, Lee CC, Chin TF, Liao SJ. Vet Hum Toxicol. Poisoning by Datura leaves used as edible wild vegetables.Vet. Hum. Toxicol. Aug 1999; 41 (4): 242-5.
8. Krenzelok EP and Mrvos R. Friends and foes in the plant world: A profile of plant ingestions and fatalities. Clin. Toxicol. 2011; 49 (3): 142 - 9. [DOI:10.3109/15563650.2011.568945]
9. French L, care RH-P emergency. undefined. Carpe Philon-An unhappy camper with vomiting and seizures. journals.lww.com. Osterhoudt, Kevin C. French, L. Keith Hendrickson, Robert G. Pediatric Emergency Care Carpe Philon-An unhappy camper with vomiting and seizures. 2010; 26 (12): 938-941. [DOI:10.1097/PEC.0b013e3182005b49]
10. America SD-E medicine clinics of N, undefined. Plant exposures: wilderness medicine. Elsevier. America SD-E medicine clinics of N, Plant exposures: wilderness medicine. Elsevier. 2004.
11. Downs C, Phillips J, Ranger A, journal LF-E medicine, 2002 undefined. A hemlock water dropwort curry: a case of multiple poisoning. emj.bmj.com. Downs C, Phillips J, Ranger A. Emerg. Med. J. A hemlock water dropwort curry: a case of multiple poisoning. 2002; 19 (5): 472-473. [DOI:10.1136/emj.19.5.472]
12. Lin TJ, Nelson LS, Tsai JL, Hung DZ, Hu SC, Chan HM, et al. Common toxidromes of plant poisonings in Taiwan. Clin. Toxicol. 2009 Feb; 47 (2): 161 - 8. [DOI:10.1080/15563650802077924]
13. Nelson L, Lewin N, Howland M and Hoffman R. Goldfrank's toxicologic emergencies. Nelson L, Lewin N, Howland M, Hoffman R. Goldfrank'stoxicologic emergencies. 2011.
14. Froberg B, Ibrahim D and Furbee RB. Plant Poisoning. Vol. 25, Emergency Medicine Clinics of North America. 2007, pp: 375 - 433. [DOI:10.1016/j.emc.2007.02.013]
15. Strzelecki A, Pichon N, Gaulier JM, Amiel JB, Champy P and Clavel M. Acute Toxic Herbal Intake in a Suicide Attempt and Fatal Refractory Ventricular Arrhythmia. Basic Clin Pharmacol Toxicol. 2010 Mar 26; 107 (2): 698 - 9. [DOI:10.1111/j.1742-7843.2010.00566.x]
16. Suchard J, … KW-A of emergency, 1998 undefined. Acute cyanide toxicity caused by apricot kernel ingestion. annemergmed.com. Suchard JR, Wallace KL, Gerkin RD. Acute cyanide toxicity caused by apricot kernel ingestion. Ann. Emerg. Med. 1998; 32 (6): 742-4. [DOI:10.1016/S0196-0644(98)70077-0]
17. Challoner K, Medicine MM-A of E. undefined. Castor bean intoxication. annemergmed.com. Challoner KR, Mc Carron MM. Castor bean intoxication. Ann. Emerg. Med. 1990; 19 (10): 1177-83. [DOI:10.1016/S0196-0644(05)81525-2]
18. Fleisher G and Ludwig S. Textbook of pediatric emergency medicine. Fleisher G, Ludwig S. Textbook of pediatric emergency medicine.Sixth edition (May 20, 2010).
19. Disease-a-Month DB- 2009 undefined. Akee fruit and Jamaican vomiting sickness (Blighia sapida Köenig). diseaseamonth.com. Barceloux DG. Akee fruit and Jamaican vomiting sickness (Blighia sapida Köenig) Disease-a-Month J. 2009; 55 (6): 318-26. [DOI:10.1016/j.disamonth.2009.03.002]
20. Weigand TJ. Clinical manifestations and evaluation of mushroom poisoning [Internet]. UpToDate. 2016 [cited 2018 Feb 11]. p. 1-12. Available from: https://www.uptodate.com/contents/clinical-manifestations-and-evaluation-of-mushroom-poisoning
21. Plenert B, Prasa D, Hentschel H and Deters M. Plant exposures reported to the Poisons Information Centre Erfurt from 2001-2010. Planta Med. 2012; 78 (5): 401 - 8. [DOI:10.1055/s-0031-1298253]
22. Fuchs J, Rauber-Lüthy C, Kupferschmidt H, Kupper J, Kullak-Ublick G-A and Ceschi A. Acute plant poisoning: analysis of clinical features and circumstances of exposure. Clin. Toxicol. 2011; 49 (7): 671 - 80. [DOI:10.3109/15563650.2011.597034]
23. Vichova P and Jahodar L. Plant poisonings in children in the Czech Republic, 1996-2001. Hum. Exp. Toxicol. 2003; 22 (9): 467 - 72. [DOI:10.1191/0960327103ht387oa]
24. Krenzelok EP. The use of poison prevention and education strategies to enhance the awareness of the poison information center and to prevent accidental pediatric poisonings. J. Toxicol. Clin. Toxicol. 1995; 33 (6): 663 - 7. [DOI:10.3109/15563659509010625]
25. Tzimenatos L, Bond GR and Group PTES. Severe injury or death in young children from therapeutic errors: a summary of 238 cases from the American Association of Poison Control Centers. Clin. Toxicol. 2009; 47 (4): 348 - 54. [DOI:10.1080/15563650902897650]
26. Carstairs SD and Cantrell FL. Peyote and mescaline exposures: a 12-year review of a statewide poison center database. Clin. Toxicol. 2010; 48 (4): 350 - 3. [DOI:10.3109/15563650903586745]
27. Zilberman M, Tavares H and El-Guebaly N. Gender Similarities and Differences: The Prevalence and Course of Alcohol and Other Substance-Related Disorders. J. Addict. Dis. 2004; 22 (4): 61 - 74. [DOI:10.1300/J069v22n04_06]
28. Tuchman E. Women and addiction: the importance of gender issues in substance abuse research. J. Addict. Dis. 2010; 29 (2): 127 - 38. [DOI:10.1080/10550881003684582]
29. Eddleston M and Warrell DA. Management of acute yellow oleander poisoning. Oxford University Press; 1999. [DOI:10.1093/qjmed/92.9.483]
30. Bandara V, Weinstein SA, White J and Eddleston M. A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning. Toxicon 2010; 56 (3): 273 - 81. [DOI:10.1016/j.toxicon.2010.03.026]
31. Eddleston M, Ariaratnam CA, Meyer WP, Perera G, Kularatne AM, Attapattu S and et al. Epidemic of self‐poisoning with seeds of the yellow oleander tree (Thevetia peruviana) in northern Sri Lanka. Trop. Med. Int. Heal. 1999; 4 (4): 266 - 73. [DOI:10.1046/j.1365-3156.1999.00397.x]

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2024 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb