year 13, Issue 52 (12-2014)                   J. Med. Plants 2014, 13(52): 41-47 | Back to browse issues page

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Soltan Dallal M, Yazdi M, Aghaamiri S, Haghighat Khajavi S, Abedi Mohtasab T, Amin Harati F et al . Antimicrobial Effect of Zataria multiflora and Rosemarinus officinalis on Antibiotic-resistant Staphylococcus aureus Strains Isolated from Food. J. Med. Plants. 2014; 13 (52) :41-47
URL: http://jmp.ir/article-1-869-en.html
1- Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , msoltandallal@gmail.com
2- Department of Pharmaceutical Biotechnology, Biotechnology Process Development Center, Pasteur Institute of Iran, Tehran, Iran
3- Department of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Behesti University of Medical Sciences, Tehran, Iran
4- Faculty of Food Sciences and Engineering, Islamic Azad University, Science and Research Branch, Tehran, Iran
5- Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
6- Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (8195 Views)
Background: Staphylococcus aureuse is one of the important pathogens which transmitted by food and has majority of habitant in human and animal community as a pathogen and normal flora. Antibiotic resistant among Staphylococcus aureuse strains is a global health challenge. Objective: Regarding to the different therapeutic and antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis in present work the antibacterial effect of this extract and its synergistic effect with routine antibiotics was investigated. Methods: In this in vitro study the antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis extract on methicillin resistant Staphylococcus aureus (MRSA) and other antibiotic resistant strains to tetracycline, erithromycine, trimethoprim, sulfamethoxazol, together with its MIC and MBC were determined. Also synergistic effect of these extracts with these antibiotics was investigated by paper disc method. Results: Shirazi Zataria multiflora, had a significant antibacterial effect against MRSA, and other Staphylococcus aureus resistant strain to tetracycline, erithromycine, trimethoprim, and sulfametoxazol, isolated from food. Conclusion: Production of a suitable herbal medicine with few side effects will give rise to a promising outlook in the treatment of infections caused by antibiotic resistant strains of Staphylococcus aureus.
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Type of Study: Research | Subject: Pharmacognosy & Pharmaceutics
Received: 2013/04/10 | Accepted: 2014/06/25 | Published: 2015/01/28

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