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:: Volume 4, Number 52 (12-2014) ::
JMP 2014, 4(52): 41-47 Back to browse issues page
Antimicrobial Effect of Zataria multiflora and Rosemarinus officinalis on Antibiotic-resistant Staphylococcus aureus Strains Isolated from Food
MM Soltan Dallal *1, MH Yazdi2, S Aghaamiri3, SH Haghighat Khajavi4, TP Abedi Mohtasab5, F Amin Harati6, M Gorbanzadeh Meshkani7
1- (Ph.D.) 1- Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , msoltandallal@gmail.com
2- (Ph.D.) 3- Department of Pharmaceutical Biotechnology, Biotechnology Process Development Center, Pasteur Institute of Iran, Tehran, Iran
3- (Ph.D. Student) 4- Department of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Behesti University of Medical Sciences, Tehran, Iran
4- (Ph.D.) 5- Faculty of Food Sciences and Engineering, Islamic Azad University, Science and Research Branch, Tehran, Iran
5- (B.Sc.) 1- Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
6- (M.Sc.) 1- Department of Pathobiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
7- (M.Sc.) 2- Food Microbiology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Abstract:   (3566 Views)
Background: Staphylococcus aureuse is one of the important pathogens which transmitted by food and has majority of habitant in human and animal community as a pathogen and normal flora. Antibiotic resistant among Staphylococcus aureuse strains is a global health challenge. Objective: Regarding to the different therapeutic and antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis in present work the antibacterial effect of this extract and its synergistic effect with routine antibiotics was investigated. Methods: In this in vitro study the antimicrobial effect of Shirazi Zataria multiflora and Rosemarinus officonalis extract on methicillin resistant Staphylococcus aureus (MRSA) and other antibiotic resistant strains to tetracycline, erithromycine, trimethoprim, sulfamethoxazol, together with its MIC and MBC were determined. Also synergistic effect of these extracts with these antibiotics was investigated by paper disc method. Results: Shirazi zataria multiflora, had a significant antibacterial effect against MRSA, and other Staphylococcus aureus resistant strain to tetracycline, erithromycine, trimethoprim, and sulfametoxazol, isolated from food. Conclusion: Production of a suitable herbal medicine with few side effects will give rise to a promising outlook in the treatment of infections caused by antibiotic resistant strains of Staphylococcus aureus.
Keywords: Rosemarinus officinalis, Staphylococcus aureus, Zataria multiform, Antibiotic Resistance, Minimum Inhibitory Concentration (MIC)
Full-Text [PDF 215 kb]   (1298 Downloads)    
Type of Study: Research | Subject: Microbiology
Received: 2015/01/28 | Accepted: 2015/01/28 | Published: 2015/01/28
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Soltan Dallal M, Yazdi M, Aghaamiri S, Haghighat Khajavi S, Abedi Mohtasab T, Amin Harati F et al . Antimicrobial Effect of Zataria multiflora and Rosemarinus officinalis on Antibiotic-resistant Staphylococcus aureus Strains Isolated from Food. JMP. 2014; 4 (52) :41-47
URL: http://jmp.ir/article-1-869-en.html
Volume 4, Number 52 (12-2014) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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