year 23, Issue 89 (3-2024)                   J. Med. Plants 2024, 23(89): 47-56 | Back to browse issues page

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Soleimani A, Fathi M, Bahrami M. The effect of ginger supplementation on inflammatory indicators and muscle damage after eccentric and concentric exercise in obese girls. J. Med. Plants 2024; 23 (89) :47-56
URL: http://jmp.ir/article-1-3582-en.html
1- Department of Sports Physiology, Faculty of Humanities, Lorestan University, Khorramabad, Iran
2- Department of Sports Physiology, Faculty of Humanities, Lorestan University, Khorramabad, Iran , helia302@yahoo.com
Abstract:   (351 Views)
Background: Some activities, such as acute activity, can cause an increase in inflammatory indicators and muscle damage in the blood. Objective: The aim of the effect of taking ginger supplement along with acute extroverted and introverted activity was on some inflammatory indicators and muscle damage in the serum of obese girls. Methods: After measuring the maximum oxygen consumption, 50 girls with a body mass index of over 30 kg/m2, age 24.89 ± 73.7 years, height 159.02 ± 5.20 cm and weight 87.77 ± 88.8 kg were randomly divided into 5 groups including: experimental group 1 [supplement+ extrovert (n = 10), experimental group 2 [supplement + introvert] (n = 10), placebo + extrovert group (n = 10), placebo + introvert group (n = 10)b , and control group (n = 10) became The training protocol included acute extroverted and introverted activity [positive and negative incline on the treadmill] was implemented. Supplement groups consumed 2 grams of ginger powder daily for 4 weeks. After fasting for at least 8 hours, blood samples were collected before and immediately after any type of activity to measure serum hs-CRP and ck levels. To examine intra-group changes, t-dependent and for inter-group comparisons, analysis of covariance with inter-group factor was used (P = 0.05). Results: The t-dependent results of this research showed that acute extroverted and introverted exercise in the pre-test and post-test, respectively, caused a significant increase in the levels of hs-CRP and CK in the supplement and placebo groups (P ≤ 0.05). Also, the results of covariance analysis showed that taking ginger supplement for four weeks after acute extroverted and introverted activity had a significant effect on hs-CRP levels (P = 0.04) between supplement and placebo groups. CK levels (P = 0.09) had no significant effect between the supplement and placebo groups. Conclusion: Increased levels of inflammation and muscle damage in introverted acute exercise are greater than in extroverted. According to the results of this research, daily consumption of ginger supplements can reduce inflammation and muscle damage caused by physical activity.
Full-Text [PDF 555 kb]   (136 Downloads)    
Type of Study: Research | Subject: Medicinal Plants
Received: 2023/11/24 | Accepted: 2024/05/15 | Published: 2024/09/11

References
1. Barzin M, Mirmiran P, Ramezankhani A, Hatami H and Azizi F. Prevalence of obesity in young Tehranian males (18-25y) entering military service. IJEM. 2009; 10(6): 605-13.
2. Beavers KM, Beavers DP, Nesbit BA, Ambrosius WT, Marsh AP, Nicklas BJ and Rejeski WJ. Effect of an 18‐month physical activity and weight loss intervention on body composition in overweight and obese older adults. Obesity 2014; 22(2): 325-31. [DOI:10.1002/oby.20607]
3. Dugravot A, Sabia S, Stringhini S, Kivimaki M, Westerlund H, Vahtera J, Guéguen A, Zins M, Goldberg M, Nabi H and Singh-Manoux A. Do socioeconomic factors shape weight and obesity trajectories over the transition from midlife to old age? Results from the French GAZEL cohort study. Am. J. Clin. Nutr. 2010; 92(1): 16-23. [DOI:10.3945/ajcn.2010.29223]
4. Tabatabai Malazi A, Larijani B. A Review of the prevalence of obesity and its management in Ira. Iran. J. Diabet. Metab. 2013; 12(5): 374-374.
5. Soheli Azad AA. Golestan B and Jahan Bakhsh S. Determination of the relation between osteoporotic and osteopenic risk factors among women referring to bmc center, Baharloo hospital. RJMS. 2008; 14(57): 91-99.
6. Calle MC and Fernandez ML. Effects of resistance training on the inflammatory response. Nutr. Res. Pract. 2010; 4(4): 259-69. [DOI:10.4162/nrp.2010.4.4.259]
7. Walker GJ, Dziubak A, Houghton L, Prendergast C, Lim L and Bishop NC. The effect of caffeine ingestion on human neutrophil oxidative burst responses following time-trial cycling. J. Sports Sci. Med. 2008; 26(6): 611-9. [DOI:10.1080/02640410701654306]
8. Silva DBD, Curty VM, Areas J, Souza SC, Hackney A and Machado M. Comparison of delorme with oxford resistance training techniques: effects of training on muscle damage markers. Biology of Sport. 2009; 77-81. [DOI:10.5604/20831862.913066]
9. Grebenyuk ES, Stupnikova TV, Sakharov DA, Shleptsova VA, Sashchenko LP and Tonevitsky EA. Long-term exercises increase the concentration of HspBP1, a co-chaperone of 70- KDa heat shock protein. Bull. Exp. Biol. Med. 2010; 149: 640-4. [DOI:10.1007/s10517-010-1013-1]
10. Calabrese V, Cornelius C, Leso V, Trovato-Salinaro A, Ventimiglia B, Cavallaro M, Scuto M, Rizza S, Zanoli L, Neri S and Castellino P. Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes. Biochim. Biophys. Acta. 2012; 1822(5): 729-36. [DOI:10.1016/j.bbadis.2011.12.003]
11. Tkáčová J and Angelovičová M. Heat Shock Proteins (HSPs): a Review. Animal Science and Biotechnologies. 2012; 45(1): 349-353.
12. Bassini-Cameron A, Sweet E, Bottino A, Bittar C, Veiga C and Cameron LC. Effect of caffeine supplementation on hematological and biochemical variables in elite soccer players under physical stress conditions. Br. J. Sports Med. 2007; 41(8): 523-30. [DOI:10.1136/bjsm.2007.035147]
13. Black CD, Herring MP, Hurley DJ and O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J. Pain. 2010; 11(9): 894-903. [DOI:10.1016/j.jpain.2009.12.013]
14. Carteron NL. Cytokines in rheumatoid arthritis: trials and tribulations. Molecular Medicine Today. 2000; 6(8): 315-23. [DOI:10.1016/S1357-4310(00)01757-3]
15. Atashak S, Peeri M, Jafari A and Azarbayjani MA. Effects of 10-week resistance training and ginger consumption on C-reactive protein and some cardiovascular risk factors in obese men. Physiol. Pharmacol. 2010; 14(3): 318-28.
16. Grzanna R, Lindmark L and Frondoza CG. Ginger -- an herbal medicinal product with broad anti-inflammatory actions. J. Med. Food. 2005; 8(2): 125-32. [DOI:10.1089/jmf.2005.8.125]
17. Mao Q-Q, Xu X-Y, Cao S-Y, Gan R-Y, Corke H, Beta T and Li H-B. Bioactive compounds and bioactivities of Ginger (Zingiber officinale Roscoe). Foods 2019; 8: 185. [DOI:10.3390/foods8060185]
18. Bizheh N, Rashidlemir A, Zabihi AR and Jafari M. The acute effect of strength training on inflammatory pathogens predicting the risk of atherosclerosis in inactive middle-aged men. Tehran University Medical Journal. 2011; 69(3): 209-204.
19. Ahmadi A, Agha Ali Nejad H, Qarakhanlu R and Zarifi A. Study of the relationship between changes in interleukin-6 [IL-6] and creatine kinase [CK] in the serum of active girls after two types of activity: introverted and extroverted maximal. Olympic Quarterly, Seventeenth Year, 2009; 46(2): 63-72.
20. Simar D, Malatesta D, Mas E, Delage M and Caillaud C. Effect of an 8-week aerobic training program in elderly on oxidative stress and HSP72 expression in leukocytes during antioxidant supplementation. J. Nutr. Health Aging. 2012; 16: 155-61. [DOI:10.1007/s12603-011-0106-5]
21. Ueda H, Ippoushi K and Takeuchi A. Repeated oral administration of a squeezed ginger (Zingiber officinale) extract augmented the serum corticosterone level and had anti-inflammatory properties. Biosci. Biotechnol. Biochem. 2010; 74(11): 2248-52. [DOI:10.1271/bbb.100456]
22. Shimoda H, Shan SJ, Tanaka J, Seki A, Seo JW, Kasajima N, Tamura S, Ke Y and Murakami N. Anti-inflammatory properties of red ginger (Zingiber officinale var. Rubra) extract and suppression of nitric oxide production by its constituents. J. Med. Food. 2010; 13(1): 156-62. [DOI:10.1089/jmf.2009.1084]
23. Soleimani A, Khosravi A and Asadi E. The effect of ten weeks of ginger consumption on lipid profile and body composition in obese women following the exercise Pilates. Tehran Univ. Med. J. 2019; 77(3): 193-198.
24. Black CD, Herring MP, Hurley DJ, O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. J. Pain. 2010 Sep; 11(9): 894-903. [DOI:10.1016/j.jpain.2009.12.013]
25. Pollock ML, Foster C, Schmidt D, Hellman C, Linnerud AC and Ward A. Comparative analysis of physiologic responses to three different maximal graded exercise test protocols in healthy women. Am. Heart J. 1982; 103(3): 363-73. [DOI:10.1016/0002-8703(82)90275-7]
26. Ellestad MH, Allen W, WAN MCK and KEMP GL. Maximal treadmill stress testing for cardiovascular evaluation. Circulation. 1969; 39: 517-22. [DOI:10.1161/01.CIR.39.4.517]
27. Ajam Zibad M, Taheri Chadorneshin H and Abtahi Eivary SH. The effect of acute resistance exercise on serum levels of some inflammatory and muscle damage markers in inactive women. Journal of Practical Studies of Biosciences in Sport. 2016; 4(7): 76-88.
28. Clarkson PM, Kearns AK, Rouzier P, Rubin R, Thompson PD. Serum creatine kinase levels and renal function measures in exertional muscle damage. Med. Sci. Sports Exerc. 2006; 38(4): 623-7. [DOI:10.1249/01.mss.0000210192.49210.fc]
29. Black CD, Oconnor PJ. Acute effects of dietary ginger on quadriceps muscle pain during moderate-intensity cycling exercise. Int. J. Sport Nutr. Exerc. Metab. 2008; 18(6): 653-64. [DOI:10.1123/ijsnem.18.6.653]
30. Gaini A, Ghasemnian A, Dehkordi Kh, Kazemi AR and Fallahi A. The comparison of the effect of one session of acute exercise on plasma levels of TNF-α, IL-6, and CRP in obese and non-obese immature boys. J. Mazandaran Univ. Med. Sci. 2011; 21(83): 78-74.
31. Vahdat Poor H, Shakarian S, Alizadeh AA and Fatemi Tabatabaei SR. The effect of short-term Ginger supplementation on serum HSCRP and creatine kinase in response to exhaustive eccentric exercise in overweight girls. Jundishapur Medical Scientific Journal, 2016; 15(5): 451-550.
32. Matsumura MD, Zavorsky GS and Smoliga JM. The effects of pre‐exercise Ginger supplementation on muscle damage and delayed onset muscle soreness. Phytother. Res. 2015; 29(6): 887-93. [DOI:10.1002/ptr.5328]
33. Padrvnd S, Hassani A, Klalian Moghadam H, Donyaei A. The effect of taking ginger supplementation and progressive endurance training on cellular damage in non-athlete men. J. Knowledge & Health. 2014; 9(2): 9-13.
34. Daryanoosh F, Hassanzadeh Kh, Haghighi, M. The effect of short-term consumption of ginger extract on delayed muscle stiffness after a training session in girls. J. Exercise Physiol. 2012; 13: 89-108. [In Persian]. https://ensani.ir/file/download/article/20130218135952-9762-122.pdf.
35. Karimi N, Roshan VD and Fathi Bayatiyani Z. Individually and combined water-based exercise with Ginger supplement, on systemic inflammation and metabolic syndrome indices, among the obese women with breast neoplasms. Iran. J. Cancer Prev. 2015; 8(6): e3856. [DOI:10.17795/ijcp-3856]
36. Baratpor M, Dabidi Roshan V and Karimi N. Tracking of changes in systemic inflammation following the Oxford resistance exercise and Ginger supplement in male volleyball players. Journal of Practical Studies of Biosciences in Sport. 2014; 1(2): 21-34.
37. Black CD, Herring MP, Hurley DJ and O'Connor PJ. Ginger (Zingiber officinale) reduces muscle pain caused by eccentric exercise. The Journal of Pain. 2010; 11(9(Supp.)): 894-903. [DOI:10.1016/j.jpain.2009.12.013]

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