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Hajiaghaee R, Bagherzadeh Z, Zarea B, Faramarzi M, Shahverdi A. Zebra Fish: Technology for Natural Product Discovery. J. Med. Plants 2009; 8 (32) :14-24
URL: http://jmp.ir/article-1-343-en.html

Rising challenges in the present drug discovery model are prompting Prompt a renewed interest in natural products as a source of novel, bioactive small molecules. With the current validation of zebra fish as a biomedical appropriate model for functional genomics and in vivo drug discovery, the zebra fish bioassay-guided identification of natural products may be an attractive tactic to generate new lead compounds in a number of indication regions. Here, we review recent natural product research using zebra fish and evaluate the potential of this vertebrate model as a discovery platform for the systematic identification of bioactive natural products.