year 3, Issue 12 (11-2004)                   J. Med. Plants 2004, 3(12): 36-40 | Back to browse issues page

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Eidi A, Eidi M, Oryan S, Fallahyan F, Darzi Darounkala R. Hypoglycaemic effect of alcoholic extract of olive (Olea europaea L.) leaf in healthy and diabetic rats. J. Med. Plants. 2004; 3 (12) :36-40
1- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran ,
2- Biology Department, Science Faculty, Varamin Unit, Islamic Azad University, Tehran, Iran
3- Biology Department, Science Faculty, Teacher Training University, Tehran, Iran
4- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran
Abstract:   (5105 Views)
In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic rats were evaluated. The results showed that oral administration of the alcoholic extract of olive exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic rats. The extract didnot change the level of blood glucose and plasma insulin in healthy rats significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 g/kg body wt.). The hypoglycaemic effect of the extract was greater than that observed with glibenclamide.
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Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2004/03/13 | Accepted: 2004/11/1 | Published: 2004/12/15

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