Eidi A, Eidi M, Oryan S, Fallahyan F, Darzi Darounkala R. Hypoglycaemic effect of alcoholic extract of olive (
Olea europaea L.) leaf in healthy and diabetic rats. J. Med. Plants 2004; 3 (12) :36-40
URL:
http://jmp.ir/article-1-726-en.html
1- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran , akram_eidi@yahoo.com
2- Biology Department, Science Faculty, Varamin Unit, Islamic Azad University, Tehran, Iran
3- Biology Department, Science Faculty, Teacher Training University, Tehran, Iran
4- Biology Department, Science Faculty, Science & Research Campus, Islamic Azad University, Tehran, Iran
Abstract: (6320 Views)
In traditional medicine leaves of olive (Olea europaea L.) are used as a diuretic, hypotensive, antibacterial and antiatherosclerotic. In the present study, oral administration of 0.1, 0.25 and 0.5g/kg body wt. of the alcoholic extract of leaves of olive for 14 days on the level of glucose and insulin in healthy and streptozotocin-induced diabetic rats were evaluated. The results showed that oral administration of the alcoholic extract of olive exhibited a significant reduction in blood glucose and increased plasma insulin in diabetic rats. The extract didnot change the level of blood glucose and plasma insulin in healthy rats significantly. A comparison was made between the action of the alcoholic extract and a known antidiabetic drug, glibenclamide (600 g/kg body wt.). The hypoglycaemic effect of the extract was greater than that observed with glibenclamide.
Type of Study:
Research |
Subject:
Pharmacology & Toxicology Received: 2004/03/13 | Accepted: 2004/11/1 | Published: 2004/12/15