سال 22، شماره 87 - ( 9-1402 )                   سال 22 شماره 87 صفحات 25-1 | برگشت به فهرست نسخه ها


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Malakootikhah J, Yahyaei M, Ghafarzadegan R, Ghafarzadegan R. Herbal nano-formulations in lung cancer: Superiorities to original forms. J. Med. Plants 2023; 22 (87) :1-25
URL: http://jmp.ir/article-1-3544-fa.html
ملکوتی‌خواه جواد، یحیائی محمد، غفارزادگان رضا، غفارزادگان رضوان. نانو فرمول‌ های گیاهی در سرطان ریه: برتری‌ ها نسبت به اشکال خالص. فصلنامه گياهان دارویی. 1402; 22 (87) :1-25

URL: http://jmp.ir/article-1-3544-fa.html


1- فارغ‎التحصیل دکتری نانوبیوتکنولوژی، دانشگاه تهران، تهران، ایران ، JMalakootikhah@ut.ac.ir
2- گروه علوم دامی، دانشکده کشاورزی و محیط زیست، دانشگاه اراک، اراک، ایران
3- مرکز تحقیقات گیاهان دارویی، پژوهشکده گیاهان دارویی جهاد دانشگاهی، کرج، ایران
4- گروه پرستاری، دانشکده علوم پزشکی خمین، دانشگاه علوم پزشکی اراک، اراک، ایران
چکیده:   (1538 مشاهده)
مقدمه: سرطان ریه (LC) شایع‌ترین نوع سرطان است و میزان مرگ و میر و عوارض آن در سراسر جهان رو به افزایش است. علی‌رغم اینکه پرتودرمانی، شیمی‌درمانی و روش‌های جراحی از جمله راهبردهای درمانی رایج در برابر LC هستند، با این وجود این روش‌ها اثربخشی کافی ندارند و ممکن است استفاده از آنها با اثرات نامطلوبی همراه باشد. در نتیجه شناسایی راه‌های جایگزین برای درمان و کنترل بیماران LC ضروری است. هدف: در این مطالعه مروری، هدف بررسی تأثیرات درمانی داروهای گیاهی مبتنی بر نانو (کورکومین، چای سبز، کورستین و مارسدنیا تناسیسیما) و مقایسه آنها با تمرکز بر جنبه‌های مکانیکی آنها در برابر LC بود. روش بررسی: پایگاه‌های اطالعاتی Scholar Google ،Science of Web ،PubMed ،Scopus و SID به طور سیستماتیک و بدون هیچ گونه محدودیتی برای زبان و زمان مورد جستجو قرار گرفتند. نتایج: نتایج ارزیابی نشان داد که این فرآورده‌های گیاهی از طریق مکانیسم‌های مختلفی مانند تنظیم سیستم ایمنی، تحریک آپوپتوز سلولی و اتوفاژی می‌توانند در درمان LC مفید باشند. با این حال، استفاده همزمان از داروهای گیاهی و فرمول‌های نانو (نانوذرات اکسیدروی، نقاط کوانتومی کادمیوم سولفید، نانوذرات کونژوگه با طلا می‌تواند به طور چشمگیری بر برخی از محدودیت‌های طب گیاهی غلبه کند و کارایی آن را در برابر LC افزایش دهد. نتیجه‌گیری: به نظر می‌رسد استفاده از نانو فرمولاسیون‌ها و داروهای گیاهی باعث بهبود LC می‌شود. با این حال، مطالعات بیشتری با حجم نمونه بزرگ برای اثبات این یافته‌ها موردنیاز است.
متن کامل [PDF 791 kb]   (906 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: گياهان دارویی
دریافت: 1402/5/1 | پذیرش: 1402/8/14 | انتشار: 1402/10/10

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