year 11, Issue 41 And S8 (supplement 8 2012)                   J. Med. Plants 2012, 11(41 And S8): 258-263 | Back to browse issues page

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Zahmatkesh M, Fallah Huseini H, Hajiaghaee R, Heidari M, Mehrafarin A, Tavakoli-far B. The Effects of Cinnamomum zeylanicum J. Presl on Blood Glucose Level in Patients with Type 2 Diabetes, a Double-blind Clinical Trial. J. Med. Plants 2012; 11 (41) :258-263
1- Farateb Research and Science Company, Tehran ,
2- Department of Pharmacology and Applied Medicine, Institute of Medicinal Plants, ACECR, Karaj
3- Department of Pharmacognosy and Pharmaceutics, Institute of Medicinal Plants, ACECR, Tehran
4- Iranian Academic Center for Education, Culture & Research (ACECR), Tehran,
5- Department of Cultivation and Development, Institute of Medicinal Plants, ACECR, Karaj
6- Department of Physiology and Pharmacology, Alborz University of Medical Science, Karaj
Abstract:   (6799 Views)

Background: Cinnamomum zeylanicum J. Presl (cinnamon) have been used as food and herbal drug in Asia and Europe. Although some studies have been shown that cinnamon has blood glucose lowering effect but some reports denied it.

Objective: This study was designed to investigate the efficacy of cinnamon on blood glucose level in patients with type 2 diabetes.

Methods: This study was a double blind randomized controlled trial study. 61 type 2 diabetic patients with fasting blood glucose of 140 to 250 mg/dl were randomly divided in to two groups. The patients in cinnamon groups received two 500mg cinnamon capsules and patients in placebo group received two 500mg placebo capsules daily.

  The patients fasting blood glucose, HbA1c, cholesterol, triglyceride, LDL and HDL were determined at starting and after 8 weeks at the end of the study.

Results: There was no significant difference in patients fasting blood glucose, HbA1c, cholesterol, triglyceride, LDL and HDL between intervention groups compared with placebo on starting of the trial. Further results indicated that there were no significant difference between two groups regarding lowering of blood glucose, HbA1c, and blood lipids after 8 week of cinnamon and placebo treatment.

Conclusion: According to the study results, consumption of one gram of cinnamon per day, do not have blood glucose lowering effects.
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Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2010/12/28 | Accepted: 2012/03/10 | Published: 2012/04/18

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