year 20, Issue 80 (12-2021)                   J. Med. Plants 2021, 20(80): 1-12 | Back to browse issues page

XML Persian Abstract Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Nasernakhaei F, Zahraei M. Halocnemum strobilaceum (Pall.) M.Bieb.: a review of its botany, phytochemistry, pharmacology and ethnobotany. J. Med. Plants. 2021; 20 (80) :1-12
1- Department of Plant Production Engineering and Genetics, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Ahvaz, Iran ,
2- Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Abstract:   (319 Views)
Background: Halocnemum strobilaceum (Pall.) M.Bieb. (Amaranthaceae) is a halophyte commonly used in traditional medicine to treat fever, jaundice, hair loss, dysmenorrhea, and headache. Other uses of H. strobilaceum include using its aerial parts extract as probiotics in aquaculture feed and a preservative in the food and beverage industries. Objective: This review will summarize the current state of knowledge available on this plant's botany, phytochemistry, pharmacology, and ethnobotany. Methods: The databases of Google Scholar, Web of Science, PubMed, Scopus, and SID were searched systematically, with no date limitation for articles published in English. Results: H. strobilaceum extracts are a rich source of anthocyanins, saponins, caffeic acid, flavonoids, coumarins, phenolic compounds, alkaloids, and fatty acids. The bioactivities ascribed to H. strobilaceum extracts are anticancer, antimicrobial, and antioxidant activities. They also can be used as insecticides against pests of stored products. Conclusion: Considering the different activities and many properties of H. strobilaceum it seems to be a suitable option for further experimental and clinical trial research.
Full-Text [PDF 406 kb]   (178 Downloads)    
Type of Study: Review | Subject: Medicinal Plants
Received: 2021/10/3 | Accepted: 2021/11/29 | Published: 2021/12/1

1. Koparde AA, Doijad RC and Magdum CS. Natural products in drug discovery. Pharmacognosy-medicinal plants. In: Pharmacognosy Medicinal Plants. 2019.
2. Katiyar C, Gupta A, Kanjilal S and Katiyar S. Drug discovery from plant sources: An Integrated Approach. Ayu 2012; 33(1): 10-19. [DOI:10.4103/0974-8520.100295]
3. Shi J, Weng JH and Mitchison TJ. Immunomodulatory drug discovery from herbal medicines: Insights from organ-specific activity and xenobiotic defenses. Elife. 2021; 10: 73673. [DOI:10.7554/eLife.73673]
4. Handoussa H, AbdAllah W and AbdelMohsen M. UPLC-ESI-PDA-MSn profiling of phenolics involved in biological activities of the medicinal plant Halocnemum strobilaceum (Pall.). Iran. J. Pharm. Sci. 2019; 18(1): 422.
5. Arya SS, Devi S, Ram K, Kumar S, Kumar N, Mann A, Kumar A and Chand G. Halophytes: The plants of therapeutic medicine. Ecophysiology, abiotic stress responses and utilization of halophytes 2019; 271-287. [DOI:10.1007/978-981-13-3762-8_13]
6. Li Y, Kong D, Fu Y, Sussman MR and Wu H. The effect of developmental and environmental factors on secondary metabolites in medicinal plants. Plant. Physiol. Biochem. 2020; 148: 80-89. [DOI:10.1016/j.plaphy.2020.01.006]
7. Acheuk F, Lakhdari W, Dahliz A, Abdellaoui K, Moukadem M and Allili S. Toxicity, acethylcolinesterase and glutathione stransferase effects of Halocnemum strobilaceum crude extract against Tribolium castaneum. Agric. For. 2018; 64(1): 23-33. [DOI:10.17707/AgricultForest.64.1.03]
8. Mariem S MK, Mariem B.J and Riadh K. Antioxidant and antimicrobial activities of Halocnemum strobilaceum fractions and their related bioactive molecules identification by GC/MS and HPLC. Res. J. Recent. Sci. 2018; 7(7): 1-9.
9. Ksouri R, Ksouri WM, Jallali I, Debez A, Magné C, Hiroko I and Abdelly C. Medicinal halophytes: potent source of health promoting biomolecules with medical, nutraceutical and food applications. Crit. Rev. Biotechnol. 2012; 32(4): 289-326. [DOI:10.3109/07388551.2011.630647]
10. Yensen NP. Halophyte uses for the twenty-first century. Ecophysiology of high salinity tolerant plants. Springer; 2008: 367-396. [DOI:10.1007/1-4020-4018-0_23]
11. Gintzburger G. Rangelands of the arid and semi-arid zones in Uzbekistan: Editions Quae; 2003.
12. Missouri Botanical Garden SL, MO & Harvard University Herbaria, Cambridge, MA. eFloras 2008. Published on the Internet Halocnemum strobilaceum.
13. Mozaffarian V. Plant taxonomy. Second book: dicotyledones. Tehran: Amir kabir press. 2004: 71-91.
14. Assadi M. Chenopodiaceae Flora of Iran, no. 38. Tehran: Research Institute of Forests and Rangelands publisher; 2001, pp: 169-175.
15. Mozaffarian V. A Dictionary of Iranian Plant Names: Latin, English, Persian. Seventh ed., Tehran: Farhang Moaser Publishers; 2013.
16. Akhani H, Ghorbanli M. A contribution to the halophytic vegetation and flora of Iran. In: Towards the rational use of high salinity tolerant plants: Springer 1993; 35-44. [DOI:10.1007/978-94-011-1858-3_4]
17. Güçlü-Üstündağ Ö and Mazza G. Saponins: properties, applications and processing. Crit. Rev. Food. Sci. Nutr 2007; 47(3): 231-258. [DOI:10.1080/10408390600698197]
18. Gibbons S, Mathew K and Gray AI. A caffeic acid ester from Halocnemum strobilaceum. Phytochem. 1999; 51(3): 465-467. [DOI:10.1016/S0031-9422(99)00007-2]
19. Bairagi SH, Salaskar PP, Loke SD, Surve NN, Tandel DV and Dusara MD. Medicinal significance of coumarins: A review. Int. J. Pharm. Res. 2012; 4(2): 16-19.
20. Radwan H and Shams K. Phytochemical and biological investigations on Halocnemum strobilaceum (Chenopodiaceae). Planta. Med. 2007; 73(09): 337. [DOI:10.1055/s-2007-987117]
21. Miftakhova A, Burasheva GS, Abilov ZA, Ahmad V and Zahid M. Coumarins from the aerial part of Halocnemum strobilaceum. Fitoterapia 2001; 72(3): 319-321. [DOI:10.1016/S0367-326X(00)00301-4]
22. Miftakhova A, Burasheva GSand Abilov ZA. Flavonoids of Halocnemum strobilaceum. Chem. Nat. Compd. 1999; 35(1): 100-101. [DOI:10.1007/BF02238224]
23. Pourabdollah Kaleybar P. Phytochemical study and Anti-cancer effects of Halocnemum strobilaceum: Tabriz University of Medical Sciences, School of Pharmacy, 2021.
24. Zaier MM, Ciudad-Mulero M, Cámara M, Pereira C, Ferreira IC, Achour L, Kacem A and Morales P. Revalorization of Tunisian wild Amaranthaceae halophytes: Nutritional composition variation at two different phenotypes stages. J. Food. Compost. Anal. 2020; 89: 103463. [DOI:10.1016/j.jfca.2020.103463]
25. Razek MA, Moussa A, El-Shanawany Mand Singab A. Comparative chemical and biological study of roots and aerial parts of Halocnemum strobilaceum growing wildly in Egypt. J. Pharm. Sci. Res. 2019; 11(9): 3289-3296.
26. Mohamed E, Kasem A and El-khatib A. Allelopathic potential of Egyptian halophytes Arthrocnemum macrostachyum and Halocnemum strobilaceum from two coastal areas. Allelopathy. J. 2020; 50: 225-241. [DOI:10.26651/allelo.j/2020-50-2-1286]
27. Lakhdari W, Dehliz A, Acheuk F, Mlik R, Hammi H, Doumandjid B, Gheriani S, Berrekbia M, Guermit K and Chergui S. Ethnobotanical study of some plants used in traditional medicine in the region of Oued Righ (Algerian Sahara). J. Med. Plants. Stud. 2016; 4(2): 204-211.
28. Zali SH and Tahmasb R. Medicinal plants of Farashband tribe's winter pastures and their traditional uses. J. Adv. Health. Med. Sci. 2016; 2(1): 18-27. [DOI:10.20474/jahms-2.1.3]
29. Heneidy SZ, Halmy MWA and Bidak LM. The ethnobotanical importance and conservation value of native plants in eastern Arabian Peninsula. Feddes. Repert. 2017; 128(3-4): 105-128. [DOI:10.1002/fedr.201600024]
30. Louhaichi M, Salkini A, Estita H and Belkhir S. Initial assessment of medicinal plants across the Libyan Mediterranean coast. Adv. Environ. Biol. 2011; 5(2): 359-370.
31. Messina CM, Renda G, Laudicella VA, Trepos R, Fauchon M, Hellio C and Santulli A. From ecology to biotechnology, study of the defense strategies of algae and halophytes (from Trapani Saltworks, NW Sicily) with a focus on antioxidants and antimicrobial properties. Int. J. Mol. Sci. 2019; 20(4): 881. [DOI:10.3390/ijms20040881]
32. Cybulska I, Brudecki G, Alassali A, Alassali M and Brown JJ. Phytochemical composition of some common coastal halophytes of the United Arab Emirates. Emirates. J. Food. Agric. 2014; 1046-1056. [DOI:10.9755/ejfa.v26i12.19104]
33. Xie W, Wang M, Chen C, Zhang X and Melzig MF. Hepatoprotective effect of isoquercitrin against acetaminophen-induced liver injury. Life. Sci. 2016; 152: 180-189. [DOI:10.1016/j.lfs.2016.04.002]
34. Yang JH, Kim SC, Kim KM, Jang CH, Cho SS, Kim SJ, Ku SK, Cho IJ and Ki SH. Isorhamnetin attenuates liver fibrosis by inhibiting TGF-β/Smad signaling and relieving oxidative stress. Eur. J. Pharmacol. 2016; 783: 92-102. [DOI:10.1016/j.ejphar.2016.04.042]
35. Rogerio A, Kanashiro A, Fontanari C, Da Silva E, Lucisano-Valim Y, Soares E and Faccioli L. Anti-inflammatory activity of quercetin and isoquercitrin in experimental murine allergic asthma. Inflamm. Res. 2007; 56(10): 402-408. [DOI:10.1007/s00011-007-7005-6]
36. Sales-Campos H, Reis de Souza P, Crema Peghini B, Santana da Silva J and Ribeiro Cardoso C. An overview of the modulatory effects of oleic acid in health and disease. Mini-Rev. Med. Chem. 2013; 13(2): 201-210. [DOI:10.2174/1389557511313020003]
37. Carrillo Pérez C, Cavia Camarero MdM, Alonso de la Torre S. Role of oleic acid in immune system; mechanism of action; a review. Nutr. Hos 2012; 27(4): 978-990.
38. Ishwarya M and Narendhirakannan R. 3, 4 Dihydroxycinnamic acid stimulates immune system function by modifying the humoral antibody response-An in vivo study. Cell. Immunol. 2017; 314: 10-17. [DOI:10.1016/j.cellimm.2017.01.006]
39. Rocha LD, Monteiro MC and Teodoro AJ. Anticancer properties of hydroxycinnamic acids-A Review. Cancer. Clin. Oncol. 2012; 1(2): 109-121. [DOI:10.5539/cco.v1n2p109]
40. Ye J-C, Hsiao M-W, Hsieh C-H, Wu W-C, Hung Y-C and Chang W-C. Analysis of caffeic acid extraction from Ocimum gratissimum Linn. by high performance liquid chromatography and its effects on a cervical cancer cell line. Taiwan. J. Obstet. Gynecol. 2010; 49(3): 266-271. [DOI:10.1016/S1028-4559(10)60059-9]
41. Kanimozhi G, Prasad N. Anticancer effect of caffeic acid on human cervical cancer cells. Coffee in health and disease prevention: Elsevier; 2015, pp: 655-661. [DOI:10.1016/B978-0-12-409517-5.00073-5]
42. Mottaghipisheh J, Nové M, Spengler G, Kúsz N, Hohmann J and Csupor D. Antiproliferative and cytotoxic activities of furocoumarins of Ducrosia anethifolia. Pharm. Biol. 2018; 56(1): 658-664. [DOI:10.1080/13880209.2018.1548625]
43. Alkorashy AI, Doghish AS, Abulsoud AI, Ewees MG, Abdelghany TM, Elshafey MM and Elkhatib WF. Effect of scopoletin on phagocytic activity of U937-derived human macrophages: Insights from transcriptomic analysis. Genomics 2020; 112(5): 3518-3524. [DOI:10.1016/j.ygeno.2020.03.022]
44. Manu KA, Shanmugam MK, Ramachandran L, Li F, Siveen KS, Chinnathambi A, Zayed M, Alharbi SA, Arfuso F and Kumar AP. Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer. Cancer. Lett. 2015; 363(1): 28-36. [DOI:10.1016/j.canlet.2015.03.033]
45. Fauser J, Matthews G, Cummins A and Howarth G. Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress. Chemotherapy 2013; 59(3): 214-224. [DOI:10.1159/000356067]

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb