Background: Diabetes is chronic and progressive disease in which lipid disorder is one of the common disorders which in turn cause the formation of its short-and long-term effects. Objective: This study was aimed to examine effect of Kombucha prepared from green tea on blood glucose and lipid profile in diabetic rats. Methods: In the present study, 30 alloxan-induced diabetic wistar rats randomly divided in to three groups: 1) control group, 2) diabetic group receiving green tea and 3) diabetic group receiving Kombucha prepared from green tea. Experimental diabetes in rats was induced by intraperitoneal injection of Aloxan (130 mg/kg). The animals of groupsgreen tea and Kombucha received respectively green tea and Kombucha (made from green tea) and group1 received water 5 ml/kg by oral gavage daily for four weeks. Then glucose and lipid profile were measured. Results: Compared to control group, Serum glucose levels in groups green tea and kombucha were significantly reduced (respectively p=0.002 and p=0.0001). Compared with green tea, Kambocha decreased glucose significantly (p=0.050). Increasing concentrations of HDL in kombucha group in comparison with green tea group was significant (p=0.02) and reduction of total cholesterol and LDL concentration in groups kombucha and green tea in comparison with control group was significant. Meanwhile, decreased average total cholesterol and LDL concentration in kombucha group in comparison with grean tea group was also significan (respectively p= 0.0001 and p =0. 0001). Conclusion: Use of Kombucha caused a decrease in serum glucose, LDL, total cholesterol and an increase in HDL cholesterolthat this effects are probably because of fermentation process products.

Background: Type 2 diabetes is a global health problem and a major cause of illness. Exercise, diet and medication are the three pillars in the treatment of type 2 diabetes. Objective: The aim of the present study was to investigate the effect of aerobic training combined with green tea hydroalcoholic extract consumption on blood glucose and lipid profile on diabetic rats. Methods: Diabetes was induced in 40 male Wistar rats by intraperitoneal injection of 50 ml/kg streptozocin. After two weeks the diabetic rats with fasting blood glucose of 150 to 300 mg/dl were divided into 4 groups of 10 rats each and named as: aerobic exercise, aerobic exercise with green tea, green tea, and control. Aerobic exercise was performed as running on Treadmill for 5 days a week daily for 30-90 minutes with Treadmill speed of 18 -24 meters per minute. Green tea extract (100 mg/kg) was gavages once a day for 5 weeks. At baseline and endpoint fasting blood glucose, cholesterol, HDL-c, LDL-c and triglyceride levels were determined in all groups. Results: Fasting blood glucose level decreased significantly in all groups but triglyceride and cholesterol decreased in aerobic exercise and aerobic exercise + green tea groups at end point compared with baseline and also compared with control group. Fasting blood LDL-c level significantly decreased and HDL-c level significantly increase, in aerobic exercise and aerobic exercise with green tea at end point compared with baseline and also compared with control and green tea group. Conclusion: Aerobic exercise favorably affects glucose and lipid profile and in combination with green tea it has synergistic effects.