Search published articles


Showing 3 results for Insulin Resistance

S Atashak, Ma Azarbayjani , M Piri , A Jafari ,
year 11, Issue 42 (5-2012)
Abstract

Objectives: Therefore, the present study investigated the effects of long-term ginger consumption and progressive resistance training on lipid per oxidation and insulin resistance in obese men. Methods: In a randomized double-blind design, 32 obese men (BMI≥ 30) were assigned in to one of four groups: a Placebo (PL,n=8), Ginger group, that consumed 1 gr ginger/d for 10 wk (GI,n=8), resistance training plus Placebo (PLRT,n=8), and 1gr ginger plus resistance exercise (GIRT, n=8). Progressive resistance training was performed three days per week for 10 weeks and included 8 exercises. At baseline and after 10 weeks venous blood samples were obtained from the antecubital vein, and Malondialdehyde (MDA) as an indicator of lipid peroxidation, pectrophotometrically were assayed by measurement of TBARS assay. Moreover, insulin resistance was determined using a homeostasis model assessment (HOMA-IR). Two-way ANOVA were used in the statistical analysis. Results: After 10 weeks of intervention, we observed a significant decrease for MDA concentration in all groups exception Placebo group (P<0.05). Moreover, significant decreases in the mean values of insulin resistance were observed in CIRT and PLRT groups (P<0.05). While it remained unchanged in GI and PL groups (p>0.05) Conclusion: Therefore, according to this results it can be said, that, long term ginger consumption and resistance training has been an effective therapeutic devise to favorable changes in lipid peroxidation and insulin resistance in obese men.

S.m Mohammadi, H Fallah Huseini , M Afkhami Ardacani , M.s Salami , S Bolurani,
year 12, Issue 46 (5-2013)
Abstract

Background: Diabetes mellitus is a metabolic disorder that is characterized by hyperglycemia due to insulin deficiency or cellular resistance. Silymarin is an effective agent that reduces cell resistance to insulin and improves lipid profile. Objective: In this study the effects of silymarin on insulin resistance and blood lipid profile in first-degree relatives of type 2 diabetic patients were evaluated. Methods: This randomized clinical trial was performed on first-degree relatives of type 2 diabetic patients (n=60) with BMI above 25 kg/m2. After completing questionnaire and obtaining written consent, participants were randomly assigned to give placebo or silymarin group. The patients in silymarin group received two 140 mg capsules of silymarin daily and placebo group 140 mg placebo capsules similarly for 12 weeks. Fasting blood glucose, HbA1c, cholesterol, triglyceride, and LDL, HDL, insulin and 2hpp blood glucose level were determined before and after the study. Results: In silymarin treated group, insulin resistance and serum insulin level were reduced significantly (p < 0.05) compared with beginning as well as compared with placebo group. The blood glucose level and lipid profile didn’t change significantly after silymarin therapy compared with placebo group. Conclusion: According to our results silymarin positively influence insulin resistance and insulin level in first-degree relatives of type 2 diabetic patients but its effect on lipid profile need further studies.

Z Zandi Dareh Gharibi , M Faramarzi , E Banitalebi ,
year 17, Issue 68 (12-2018)
Abstract

Background: Visfatin is protein with insulin-like function that is expressed in high levels in visceral fat tissue and its circulating levels is associated with obesity and diabetes.
Objective: The purpose of this study was to examine the effect of 10 weeks of rhythmic aerobic exercise and green tea supplementation on visfatin levels and insulin resistance in obese type II diabetic women.
Methods: 46 obese diabetic women (BMI>30) 45 -60 years old were selected and randomly assigned into four groups of green tea (n=12), aerobics + green tea (n=12), aerobics (n=12) and control (n=10) groups. Subjects in green tea supplementation group received 1500 mg capsules containing green tea extract daily for 10 weeks. Also exercises were performed three sessions a week in a ten week period. The analysis of variance with Tukey test and dependent t-test were used to within and between groups analysis.
Results: The results showed that visfatin have significant difference between groups (P=0.001) however, there was no significant difference between interventions. Also, there was no significant differences between interventions for HOMA, insulin and glucose.
Conclusion: Although there are no significant differences between interventions, significant reduction of visfatin after aerobic exercise and consumption of green tea may be due to improvements in glycemic index and weight loss and the HOMA index. Therefore, it seems that supplementation with green tea along with aerobic exercise may influence weight control and improved glycemic index in  type II diabetic patients.


Page 1 from 1     

© 2025 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb