Showing 11 results for Raza
Aa Basti , V Razavilar , A Misaghi , R Abbasifar , B Radmehr, F Khalighi Sigaroodi ,
year 3, Issue 9 (2-2004)
Abstract
The growing interest in the substitution of chemical food preservatives, both antimicrobials and antioxidants, by natural ones has fostered research on the vegetable source and screening of plant extracts and essential oils in order to identify acceptable natural alternatives. In this study, log probability percentage (Log P%) of growth of Salmonella typhimurium in Brain Heart Infusion (BHI) broth as affected by different concentrations of Zataria multiflora Boiss essential oil (0.0, 0.03 and 0.06%) during 21 days storage at three temperatures (35, 25 and 15ºC) was investigated. The Log P% of S. typhimurium was affected significantly (P < 0.05) by different concentrations of the essential oil. The Log P% of S. typhimurium in BHI broth with 0% essential oil at 35, 25 and 15ºC were 1.07, 1.07 and 0.41 respectively. While in BHI broth with 0.03 and 0.06% essential oils were -2.93, -3.24 and -4.23 and -4.23, -4.23 and -4.23 respectively. According to the results, the Log P% of growth of S. typhimurium was decreased by increasing of the concentration of essential oil.
Aa Basti , V Razavilar , A Misaghi , B Radmehr , R Abbasifar , D Yazdani , S Akhondzadeh ,
year 3, Issue 10 (5-2004)
Abstract
The growing interest in the substitution of chemical food preservatives, both antimicrobials and antioxidants, by natural ones has fostered research on the vegetable source and screening of plant extracts and essential oils in order to identify acceptable natural alternatives. In this study, log probability percentage (Log P%) of growth of Staphylococcus aureus in Brain Heart Infusion (BHI) broth as affected by different concentrations of Zataria multiflora Boiss essential oil (0.0, 0.03 and 0.06%) during 22 days storage at three temperatures (35, 25 and 15ºC) was investigated. The Log P% of S. aureus was affected significantly (p < 0.05) by different concentrations of the essential oil. The Log P% of S. aureus in BHI broth with 0% essential oil at 35, 25 and 15ºC were –0.89, 1.24 and 1.55 respectively. While in BHI broth with 0.03 and 0.06% essential oils were -0.45, 0.24 and -4.21 and -0.45, -0.45 and -4.45 respectively (strong inhibitory action).
Ma Soltani Poor , Mb Rezaei , A Moradshahi , B Kholdebarin , Mm Barazandeh ,
year 6, Issue 21 (3-2007)
Abstract
Background: Zhumeria majdae is one of the most important, unic and endomic species of Hormozgan Province which used for diarrhoea, stomachache, cold, headache, wound and also as coolness from from ancient times by natives people of Hormozgan. Objective: The aim of the present study was to detect and compare the constituents of the essential oils of Zhumeria majdae at flowering stage in Geno, Sarchahan and Tangezagh mounts regions of Hormozgan Province. Methods: The leaves of Zhumeria majdae were collected at flowering stages. The essential oil of the leaves obtained by hydrodistillation using Clevenger type apparatus, was analysed by GC and GC/MS. Results: Essential Chromatogram of Zhumeria majdae shows that in Geno mount’s species 17 compounds, in Sarchahan mount’s 22 compounds and in Tange zagh mount’s 14 compounds, were exist. Oil yeild in that three regions were, in turne, 6.2, 6.1 and 5.3 percent. Linalool and Camphore were major compounds. Gama Terpinene, Octa 3-Carene ,Octan-3-one, Myrcene, Beta Bisabulene,Thymole and Terpinolene in Geno mount, Cis and Trans Linalool oxide, Linalool, Camphore, Neral, Geraniol, Geranial, Beta Elemene and Alpha Terpineol in Sarchahan mount and Alpha Pinene, Camphene, Orto Cymene, Limonene, Borneol, Nerol and Cis Jasmone in Tangezagh mount were more than other compounds. Conclusion: The numbers and contents of constituents of essential oils of Zhumeria majdae at flowering stages in various parts of Hormozgan province are different.
Mm Barazandeh , K Bagherzadeh,
year 6, Issue 23 (9-2007)
Abstract
Background: Thymus species are of very important medicinal plants which are being used very much. The properties of essential oils of various Thymus species are related to Thymol and Carvacrol. Essential oils of the leaves and flowers of Thymus have antispasm, antiflatulence, anti rheumatism effects and are strong disinfectants. In pharmaceutics their essential oils are used for preparation of mouth washing solutions and anticough syrups. Objective: The purpose of this research is an investigation on the essential oils composition of Thymus daenensis Celak from four locations of Isfahan province in order to identify the most premium essential oil. Methods: The aerial parts of Thymus daenensis Celak in the flowering stage were collected in Aug. 2004 from Isfahan, Golpayegan, Samirom and Daran in Isfahan province of Iran and after drying at room temperature, were hydrodistilled for 2 h using a Clevenger-type apparatus.The essential oils were analysed by GC and GC/MS. Results: Essential oils were produced at the yields of 3.4% (Isfahan), 3.9% (Golpayegan), 3.05% (Samirom) and 3.2% (Daran), respectively. Twenty-seven compounds were identified among which thymol (51.3%-78.3%), p-cymene (2.7%-7.6%), γ-terpinene (2.7%-10.1%), carvacrol (2.0%-9.2%) and β-caryophyllene (2.4%-4.3%) were the major constituents, respectively. Conclusion: Samirom sample has the most effective properties of essential oil although it has the lowest yield.In the other hand Golpayegan sample has the highest yield of essential oil in spite of it’s lowest essential oil properties.So if it is desired to obtain the highest yield, the Golpayegan sample is the best one and if it is desired to produce the essential oil with the most effective properties, the Samirom sample is the best one.
H Fallah Huseini , A Zaree Mahmodabady , R Heshmat , M Raza ,
year 8, Issue 29 (Supplement 5 2009)
Abstract
Background: Increased oxygen free radical and reduced glutathione level in the eye lens are important risk factor for cataract formation. The antioxidative property and increasing cellular and extra cellular glutathione level have been reported by several herbal medicines including silymarin.
Objective: In present interventional study Silybum marianum L. seed extract (silymarin) was tested against galactose-induced cataract development in rats.
Methods: Thirty male 45 days old wistar rats (150 – 200 g), were divided in three groups of 10 rats each. Cataract was induced in two groups of rats following feeding them with 30% galactose diet for 40 days. One group kept as control and silymarin in the dose of 200 mg/kg/d was administered orally (mixed with galactose diet) to other group for 40 days. Cataract development in the rats lens was observed daily by ophthalmoscope and naked eye during the study. The glutathione (GSH) and lipid peroxides (LPO) levels were determined after 20 days in all rats left eye lens.
Results: The results indicated that, in silymarin treated group all stage of cataract development were significantly delayed as compared to control group. In rats treated with silymarin the lens GSH level was increased significantly (p<0.01) and LPO levels was decreased significantly as compared to control group (p<0.05).
Conclusion: Administration of silymarin to galactose fed rats showed beneficial effect on prevention of cataract development as well as antioxidative defence system such as increase in lens GSH and decrease LPO levels.
M Rahnama , Sm Razavi Rohani , H Tajik , F Khalighi-Sigaroodi , M Rezazad - Bari ,
year 8, Issue 32 (12-2009)
Abstract
Background: In food industry, quality assurance and prolongation of shelf-life is achieved through control of pathogenic and spoilage microorganisms in foods. Regards to much proved adverse effects of synthetic food additives and general concern on the subject, the replacement of these additives with natural based ones such as plant essential oils and natural antibiotics has been raised and researches first at in vitro models and then in food systems is necessary. Objectives: The aim of this study was to determine the antimicrobial activity, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Zataria multiflora Boiss. essential oil and nisin alone and in combination against Listeria monocytogen in brain heart infusion (BHI) broth. The specifications of combination of essential oil and nisin were determined. Methods: In this study 600 µg/ml of Z. multiflora essential oil and 2.5 µg/ml nisin in pH value of 5 at 15 ºC were used. Results: In this study Zataria multiflora essential oil had antimicrobial effects agains Listeria monocytogen (MBC: 19, MIC: 9.5µg/ml). Combination of nisin and the essential oil had also antimicrobial effects against Listeria monocytogen (MIC: 1.2, MBC: 2.4µg/ml). Conclusion: Zataria multiflora essential oil and nisin were effective against Listeria monocytogen alone. This effect was obviously increased in combination with each other and the results were noticeable.
M Moradi , H Tajik, S.m Razavi Rohani , A Oromiehie , H Malekinejad , H Ghasemmahdi,
year 11, Issue 42 (5-2012)
Abstract
Background: The application of antioxidant films is a promising strategy for controlling chemical spoilage of food. Objectives: Antioxidant chitosan films incorporated with grape seed extract (GSE) were developed with the objectives of investigation of their characteristics. Methods: Chitosan film was developed by casting method and the effect of different concentrations of GSE (0, 0.5, 1 and 2%) on mechanical, color (accordance with hunter system [L* (luminosity), α* (redness), and b* (yellowness)], antioxidant characteristics, total phenol (TP), and swelling index (%SI) of films were evaluated. Results: Generally, the tensile strength of GSE formulated films was influenced by the concentrations of GSE. The 2% GSE/ chitosan films revealed tensile strength similar to unsupplemented film. Concerning color of chitosan film, results indicated that by incorporating GSE, significant changes on L*, α*, b* values were appeared (p0.05). The antioxidant activity of GSE formulated films was considerable due to the high source of phenolics. This activity was affected by GSE concentrations, which were significant for film containing 0.5% (37.85%) 1% (39.16%) and 2% (41.57%) GSE in comparison with control (12.34%) (p 0.05). The results also revealed that by increasing the amount of GSE, the TP and %SI were significantly increased. Conclusion: The results indicated that all characteristics of films were influenced by the extent of GSE. Improvement in antioxidant and total phenol of GSE assimilated films is appreciated. Such films are suitable for handle in preserving food.
A Akhondzadeh Basti, M Aminzare, Sm Razavi Rohani , A Khanjari , N Noori , A Jebelli Javan , A Taheri Mirghaed, M Raeisi , H Naghili , F Mohammadkhan ,
year 13, Issue 50 (5-2014)
Abstract
Background: Various studies have been conducted to show the effects of essences and enzymes on foodborne pathogens in culture media. Objective: The aim of this study was to determine the effect of Zataria multiflora Boiss. essential oil and lysozyme alone and in combination on preventing growth of Vibrio parahaemolyticus in culture media. Methods: In this study, the MIC of Zataria multiflora Boiss. essential oil and lysozyme, together and alone, on Vibrio parahaemolyticus, was determined by using macro and microdilution methods. Results: The MIC of Zataria multiflora essential oil determined 0.01% and 0.02% by using macro and microdilution methods, respectively and lysozyme at 1000 mg/mL concentration could not inhibit the growth of V. parahaemolyticus. Conclusion: According to the results of current study, Zataria multiflora essential oil showed better results in comparison with lysozyme, moreover Applying lysozyme and essential oil together did not decrease MIC, but extended the latent phase of V. parahaemolyticus, which considered an important factor in microbiology.
Zeynab Razavi Majd, Hassan Matin Homaee, Mohammad Ali Azarbayjani, Parvin Farzanegi,
year 16, Issue 62 (5-2017)
Abstract
Background: One of the problems due to aging is apoptosis development in various tissues of body. There is some evidence that some drugs induce apoptosis development via oxidative stress. However, physical activity and herbal drugs through two different mechanisms can cause to inhibit the apoptosis.
Objective: The aim of this study was to investigate the effects of concurrent regular aerobic training and garlic extract on Bax and Bcl-2 levels and Bax to Bcl-2 ratio in cardiac tissue of aged rats with chronic kidney disease.
Methods: Forty two aged male rats were selected and randomly divided into control group, Doxorubicin group, Doxorubicin and saline group, Doxorubicin and aerobic training group, Doxorubicin and garlic group, Doxorubicin, garlic and aerobic training group. The chronic kidney disease induced by the subcutaneous injection of doxorubicin (8.5 mg/kg of body weight) .The protocol training included 3 sessions per week, 30 minutes per session for 8 weeks. The garlic extract were given by gavage (2.5 g/kg of body weight). Cardiac levels of Bax and Bcl-2 were measured by ELISA.
Results: The results showed that eight weeks swimming training and garlic extract and combination of them caused to significant increase in Bcl-2 levels and significant decrease in Bax levels and Bcl-2 to Bax ratio of aged cardiac tissue rats with chronic kidney disease (P<0.05).
Conclusion: Based on the results, although physical training and garlic extract individually imposed protective effects on the cardiac tissue but intervention effect of them had no reinforcement effect on the cardiac protection.
A Jafari-Koulaee, F Khenarinezhad, A Sharifi Razavi, M Bagheri-Nesami,
year 18, Issue 70 (5-2019)
Abstract
Background: Disability due to headache in migraine and being chronic of it can lead to sadness and depression.
Objective: This study was aimed to determine the effect of lavender aromatherapy on depression and headache disability.
Methods: This clinical trial study was conducted on 60 migraine patients referred to Toba Clinic of Sari (Mazandaran, Iran) during 2016-2017. Patients in the experimental group inhaled 2-3 drops of lavender essence for 15 min, three times a week for 4 consecutive weeks. The dose, duration and inhalation method of paraffin (as placebo) in control group were similar to those in the experimental group. Before the intervention, at the end of the second and fourth weeks, the intensity of depression and headache disability were measured by Beck Depression Inventory (BDI-13) and Jacobson questionnaire. For analyzing in each group and groups, repeated measure tests and Boneforeni were used.
Results: In experimental group, depression (P <0.001, F=64.49) and headache disability scores
(P <0.001, F=29.95) were significantly different in the pre intervention, two and four weeks after the intervention. No statistically significant differences were observed between the two groups in terms of the depression (P = 0.13, f = 2.6) and headache disability (P = 0.15, f = 1.93) scores before, two and four weeks after intervention.
Conclusion: Lavender essential oil can be useful for reducing depression and headache disability in migraine patients.
Maryam Hakimi, Reza Shiari, Afshan Shirkavand, Mohammadreza Razaghi, Shirin Farivar,
year 23, Issue 89 (3-2024)
Abstract
Background: Prostate cancer is known as the second common cancer among men, and is introduced as the fifth cause of death. Apoptosis known as “Programmed Cell Death”, can be measured as a defense mechanism in response to cell damage, caused by diseases or exposure to toxic material, and has an important role in controlling cell population. For this, researchers are interested in studying cancer treatment for inducing apoptosis. Flaxseed, Linum usitassimum, has numerous benefits among other oilseeds. It contains a large amount of α-Linoleic Acid (ALA), dietary fiber, proteins, and Phytoestrogen. Objective: The main goal of this research was to evaluate the expression of apoptotic genes induced with flaxseed extract in human prostate cancer cells in order to find out the cell death pathway induced by flaxseed extract. Methods: In this study, PC-3 prostate cancer cells were cultured and the treatments were done using the flaxseed extract. The MTT test, IC50 calculations, Flowcytometry, and Real-Time PCR test for apoptotic genes were done and all the results underwent analysis. Results: The IC50 dose was obtained at 809 µg/ml (P < 0.05). Flowcytometry test was done for 600, 800, and 1000 µg/ml of extraction, and the result showed that most of the cells underwent necrosis. The Flowcytometry result was confirmed by qPCR test and showed the overexpression of TNF gene (P < 0.05). Conclusion: The results showed the overexpression of all the studied genes after treatment by flaxseed extract. The Flowcytometry result was confirmed by qPCR and showed that the TNF gene was overexpressed.
