سال 11، شماره 41 - ( English 1390 )                   سال 11 شماره 41 صفحات 66-77 | برگشت به فهرست نسخه ها

XML English Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Qaderi A, Omidi M, Etminan A, Oladzad A, Ebrahimi C, Dehghani Mashkani M et al . Hazel (Corylus avellana L.) as a New Source of Taxol and Taxanes. J. Med. Plants. 2012; 11 (41) :66-77
URL: http://jmp.ir/article-1-155-fa.html
Qaderi A، Omidi M، Etminan A، Oladzad A، Ebrahimi C، Dehghani Mashkani MR و همکاران.. Hazel (Corylus avellana L.) as a New Source of Taxol and Taxanes. فصلنامه گياهان دارویی. 1390; 11 (41) :66-77

URL: http://jmp.ir/article-1-155-fa.html


1- Department of Biotechnology of Medicinal Plants, Institute of Medicinal Plants, ACECR, Karaj, Iran
2- Department of Agronomy and Plant Breeding, Faculty of Agriculture, Tehran University, Tehran, Iran
3- Department of Plant Breeding, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran
4- Department of Cultivation and Development, Institute of Medicinal Plants, ACECR, Karaj, Iran
5- Department of Cultivation and Development, Institute of Medicinal Plants, ACECR
چکیده:   (4670 مشاهده)
Taxol is used to treatment of variety cancers including ovarian, breast, lung, head and neck carcinomas and the AIDS-related Karposi’s carcinoma, and was originally obtained from bark of taxus brevifolia. However the amount of extracted taxol from taxus is extremely low and cannot be considered as a suitable commercial source and it has led to studies for finding new sources of Taxol. In 1998, Angela Hoffman and her team reported that hazel could be as a taxol-producing species and it has been confirmed by recent studies. On the other hand, the genes and enzymes involved in taxol biosynthesis pathway in taxus sp. have been identified and characterized but because of very slow growth and difficult somatic embryogenesis, manipulation of taxus is restricted. Instead, hazel with widely contribution in the world, easy invitro culture and characterization of some genes involved in the pathways of MVA and DXP (such as HMGR, IPI and GGPP), makes possibility of manipulation of taxol biosynthesis pathway. In this paper we reviewed a summary of genetic and biotechnology studies on hazel.
واژه‌های کلیدی: Taxol، Hazel، MVA pathway، DXP or MEP pathway
متن کامل [PDF 207 kb]   (2576 دریافت)    
نوع مطالعه: پژوهشی | موضوع مقاله: فارماكوگنوزی و فارماسيوتيكس
دریافت: 1390/1/16 | پذیرش: 1390/12/1 | انتشار: 1390/12/28

ارسال نظر درباره این مقاله : نام کاربری یا پست الکترونیک شما:
CAPTCHA

بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.

کلیه حقوق این وب سایت متعلق به فصلنامه علمی پژوهشی گیاهان دارویی می باشد.

طراحی و برنامه نویسی : یکتاوب افزار شرق

© 2021 CC BY-NC 4.0 | Journal of Medicinal Plants

Designed & Developed by : Yektaweb