year 1, Issue 3 (9-2002)                   J. Med. Plants 2002, 1(3): 85-89 | Back to browse issues page

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Noorian M, Forghani B, Amini M. A comparative study on the effects of wheat bran and ispaghula on serum lipids and fasting blood sugar in type 2 diabetic patients. J. Med. Plants. 2002; 1 (3) :85-89
1- Faculty of Public Health, Isfahan University of Medical Sciences
2- Endocrinology Research Center, Isfahan University of Medical Sciences
3- Faculty of Medicine, Isfahan University of Medical Sciences ,
Abstract:   (6148 Views)
In this study, the effects of wheat bran (insoluble) and ispaghula (soluble) seeds on serum lipids and FBS have been compared in type 2 diabetic patients. In a cross over study, 14 type 2 diabetic patients, treated with diet alone, were randomly placed on isocaloric diets containing either wheat bran (7 patients) or ispaqhula (12 grams/day in both groups) for 3 weeks. After a 10-day wash-out period, dietary fiber supplementation was exchanged and diets were continued for 3 weeks again. Weight, FBS, total cholesterol, LDL and HDL were measured before and after the study. Food records and the differences observed in serum variables were analyzed using Willcoxon non- parametric method and paired t-test respectively. P<0.05 was considered significant. The participants were 4 men and 10 women aged 45±1 years (BMI= 23±1.9 kg/m²). Both wheat bran and ispaghula increased the serum HDL (P<0.01 and P<0.001 respectively). Serum LDL was decreased after consumption of ispaghula (P<0.02). Our results show that dietary intake of fibers, especially in soluble from, can improve lipid profile in type 2 diabetic patients.
Full-Text [PDF 134 kb]   (1382 Downloads)    
Type of Study: Research | Subject: Pharmacology & Toxicology
Received: 2001/06/11 | Accepted: 2002/08/20 | Published: 2002/09/3

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