year 5, Issue 20 (12-2006)                   J. Med. Plants 2006, 5(20): 21-26 | Back to browse issues page

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Dakhili M, Zahraei Salehi T, Torabi Goodarzi M, Khavari A. Evaluation of Antimicrobial Effects of 4 Medicinal Plants Against Salmonella typhymurium and Comparision them with Common Antibiotics in Veterinary Medicine. J. Med. Plants 2006; 5 (20) :21-26
1- Assistant Professor of Microbiology and Immunology Department, Faculty of Medicine, Islamic Azad University of Qom, Iran
2- Associate Professor of Microbiology and Immunology Department, Faculty of Veterinary Medicine, University of Tehran, Iran ,
3- Departments of Veterinary Medicine, Agriculture and Natural Resources Research Center of Qom, Iran
Abstract:   (5961 Views)
Background: Thyme (Zataria multiflora Bois.), Penny voyel (Mentha pulegium L.) Origanum (Origanum vulgare L.) and Fennel (Foeniculum vulgare Miller) are the Iranian traditional spice which are widely used in the country. Following the recent efforts to look for healthy remedies with antimicrobial potential, the effects of essential oils of these medicinal plants were investigated on Salmonella typhimurum. Objective: Chemical composition and antimicrobial effects of essential oils from plants were evaluated on Salmonella typhimurum and compared with five antibiotics enrofloxacin, chloramphenicle, erytromycin, oxytetracyclin and flumequin. Methods: The essential oils of the leavs and stems are obtained from each plants by hydrodistillation and clevenger and analyzed by GC/MS. Results: The results of this study show that Thyme oil, compared to flumequin, oxytetracyclin and erythromycin is more effective (P<0.5). Essential oil of Penny voyel is more effective than oxytetracyclin and erythromycin. Among essential oil of plants, Thymol oil with minimal inhibitory concentration) MIC) 156.5µg/ml and minimal bactericidal concentration (MBC) 312.5 µg/ml had the best result against Salmonella typhimurum. Chemicial compounds: Thymol, Carvacrol and α -terpinen were found in Z. multiflora, M. pulegium, O. vulgar and F. vulgare by GC analyse. Conclusion: Considering the significant antibacterial effect of essential oil of Z. multiflora on effect on Salmonella typhimurum in invitro, it is recommened that, the therapeutic effect of this essential oil be studied in invivo.
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Type of Study: Research | Subject: Pharmacognosy & Pharmaceutics
Received: 2005/03/13 | Accepted: 2006/11/25 | Published: 2007/01/21

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