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:: Volume 4, Number 48 (12-2013) ::
JMP 2013, 4(48): 54-61 Back to browse issues page
Comparative Effects of Alcea sulphurea and Bromhexine HCL on Mucociliary System of Chicken Trachea
SMH Noori moogahi *1, M Khanehzad2, M Sadr3, SH Roholahi4, SM Kameli5
1- Ph.D. Faculty of Medicine, Tehran University of Medicla Scinces , noorimoo@gmail.com
2- (MS.c. Student) Faculty of Medicine, Tehran University of Medicla Scinces
3- (Ph.D Student) Faculty of Medicine, Tehran University of Medicla Scinces
4- (Ph.D. Student) Faculty of Veterinary Medicine, Tehran. University
5- (M.Sc.) Faculty of Medicine, Tehran University of Medicla Scinces
Abstract:   (2962 Views)
Background: Alcea sulphurea (A.S) with various drug effects, especially on mucociliary system as dilutor drug and sputum collection is known. Objective: This study examined the comparative effects of A.S and Bromhexine HCL (B.H) on mucociliary system chicken trachea. Methods: In this experimental study 30 Leghorn chickens were randomly divided into five groups of six. One group was considered as Control and the other four groups during 12 days received oral B.H, oral A.S extract, nebulas normal saline and Nebulized A.S extract respectively. After 12 days the chicks were killed and the biopsy samples from the middle tracheal were taken for histopathology study using PAS methods under Light microscopy. Finally Image tools III Software were used for counting of size and number of mucous glands and cilia. Results: Results of the analysis of data showed a significant increase of number and the size of mucous glands, also the size of cilia in Nebulized A.S group in comparison to Control group, oral B.H, normal saline .The oral A.S extract group showed the increase in numbers and sizes of cilia and mucous glands but they weren’t significant. Conclusion: According to more mucolytic effects of A.S extract than Bromhexine HCL and side effects for drugs mucolytic is recommended to be used that respiratory and inflammatory diseases of the A.S extract.
Keywords: Alcea sulfueae, Bromhexine HCL, Chicken trachea, Mucociliary system
Full-Text [PDF 653 kb]   (735 Downloads)    
Type of Study: Research | Subject: Anatomy
Received: 2014/09/29 | Accepted: 2014/09/29 | Published: 2014/09/29
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Noori moogahi S, Khanehzad M, Sadr M, Roholahi S, Kameli S. Comparative Effects of Alcea sulphurea and Bromhexine HCL on Mucociliary System of Chicken Trachea. JMP. 2013; 4 (48) :54-61
URL: http://jmp.ir/article-1-60-en.html
Volume 4, Number 48 (12-2013) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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