year 8, Issue 30 (5-2009)                   J. Med. Plants 2009, 8(30): 92-97 | Back to browse issues page

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Kasra Kermanshahi R, Nasr Esfahani B, Pour babaie A, Asghari G, Esmi Serkani J. The Study of Antibacterial Effect of Humulus lupulus on some of Gram Positive & Gram Negative Bacteria. J. Med. Plants 2009; 8 (30) :92-97
1- Department of Microbiology, School of Sciences , Alzahra University, Tehran, Iran ,
2- Department of Microbiology, School of medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3- Department of Microbiology, Islamic Azad University of Qom, Qom, Iran
4- Department of Pharmacognosy, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract:   (7674 Views)
Background: In recent years, a new view has been stablished toward pharmaceutical plants and applicational use of them all over the world and researchers, in various medical courses are investigating about this issue. Objective: On this basis, antibacterial effect of Humulus lupulus, the pharmaceutical plant which has an important place in traditional medicine of Iran, was evaluated on some of bacteria. Methods: Based on scientific methods after being dried, prepared extract by using macerasion method. Antibacterial effects of ethanol extract were studied on Staphylococcus aureus (1112PTCC), Escherichia coli (1276PTCC), Bacillus subtilis (1023PTCC), Psedomonas aeroginosa (1430PTCC), by using spreading method, well plate method and MIC. Results: The ethanol extract of Humulus lupulus showed antimicrobial activity on S. aureus and B. subtilis. The extract exhibited antimicrobial activity at a range of 125 mg/ml to 62/5 mg/ml against S. aureus and B. subtilis respectively. Conclusion: With the increase of worldwide antibiotic resistance of many strains of disease producing bacteria, there is a need to access new and complementary approaches to antibiotic therapy. Extract of Humulus lupulus has antibacterial effect. The antimicrobial activity of Humulus lupulus against a variety of gram positive bacteria confirm its use for treatment of infectious.
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Type of Study: Research | Subject: Pharmacognosy & Pharmaceutics
Received: 2007/12/8 | Accepted: 2009/03/4 | Published: 2009/06/19

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