year 18, Issue 72 (11-2019)
J. Med. Plants 2019, 18(72): 255-263 |
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Ghorbanian B, Saberi Y, Azali Alamdari K, Shokrollahi F, Mohammadi H. The Effects of Portulaca Supplementation on Antioxidant Biomarkers and Oxidative Stress in non-Active Girls. J. Med. Plants 2019; 18 (72) :255-263
URL: http://jmp.ir/article-1-2720-en.html
URL: http://jmp.ir/article-1-2720-en.html
1- Associate Professor of Exercise Physiology, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran , b.ghorbanian@azaruniv.ac.ir
2- Ph.D. student of Exercise Physiology, Faculty of Sport Sciences, Urmia University, Urmia, Iran
3- Associate Professor of Exercise Physiology, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran
4- Master of Sport Physiology, Shahid Madani University, Tabriz, Iran
2- Ph.D. student of Exercise Physiology, Faculty of Sport Sciences, Urmia University, Urmia, Iran
3- Associate Professor of Exercise Physiology, Department of Sport Sciences, Faculty of Education and Psychology, Azarbaijan Shahid Madani University, Tabriz, Iran
4- Master of Sport Physiology, Shahid Madani University, Tabriz, Iran
Abstract: (3927 Views)
Background: Oxidative stress results from imbalance in the body's redox position, which results in tissue damage due to increased intracellular radicals. Antioxidants prevent the oxidation of fatty acids and prevent foam cells and atherosclerotic plaque. Portulaca, which is one of the supplements, is considered as an antioxidant-rich plant.
Objective: The purpose of this study was to evaluate the effect of eight weeks of Portulaca supplementation on antioxidant enzymes and oxidative stress in non-active girls.
Methods: This quasi-experimental study was conducted on non-active girls (overweight and obese) with an age range of 20-30 years in Azarbaijan Shahid Madani University. 20 subjects were qualified and randomly divided into two control (n = 10) and complement (n = 10) groups. Subjects of supplemented group received 1200 portulaca mg per day for eight weeks. Data were analyzed by t-test using by SPSS20 software. Statistical significance criterion was set as P<0.05.
Results: The results showed that serum levels of superoxide dismutase (SOD), glutathione peroxidase(GPX) and total antioxidant capacity (TAC) were significantly increased in the supplemented group (P<0.05), while the amount of malondialdehyde (MAD) decreased, this decline was not statistically significant (P> 0.05).
Conclusion: Portulaca supplements are likely to be effective in improving cardiovascular health and preventing cardiovascular disease and strengthening the antioxidant system in overweight and obese people, and destroys lipid peroxidation that produces ROS.
Objective: The purpose of this study was to evaluate the effect of eight weeks of Portulaca supplementation on antioxidant enzymes and oxidative stress in non-active girls.
Methods: This quasi-experimental study was conducted on non-active girls (overweight and obese) with an age range of 20-30 years in Azarbaijan Shahid Madani University. 20 subjects were qualified and randomly divided into two control (n = 10) and complement (n = 10) groups. Subjects of supplemented group received 1200 portulaca mg per day for eight weeks. Data were analyzed by t-test using by SPSS20 software. Statistical significance criterion was set as P<0.05.
Results: The results showed that serum levels of superoxide dismutase (SOD), glutathione peroxidase(GPX) and total antioxidant capacity (TAC) were significantly increased in the supplemented group (P<0.05), while the amount of malondialdehyde (MAD) decreased, this decline was not statistically significant (P> 0.05).
Conclusion: Portulaca supplements are likely to be effective in improving cardiovascular health and preventing cardiovascular disease and strengthening the antioxidant system in overweight and obese people, and destroys lipid peroxidation that produces ROS.
Type of Study: Research |
Subject:
Pharmacology & Toxicology
Received: 2018/06/13 | Accepted: 2018/10/21 | Published: 2019/10/28
Received: 2018/06/13 | Accepted: 2018/10/21 | Published: 2019/10/28
References
1. Greenberg AS and Obin MS. Obesity and the role of adipose tissue in inflammation and metabolism. Am. J. Clin. Nutr. 2006; 83 (2): 461S-465S. [DOI:10.1093/ajcn/83.2.461S]
2. Mathieu P, Poirier P, Pibarot P, Lemieux I and Després JP. Visceral obesity: the link among inflammation, hypertension, and cardiovascular disease. Hypertension 2009; 53 (4): 577-84. [DOI:10.1161/HYPERTENSIONAHA.108.110320]
3. Masella R, Di Benedetto R, Varì R, Filesi C and Giovannini C. Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J. Nutr. Biochem. 2005; 16 (10): 577-86. [DOI:10.1016/j.jnutbio.2005.05.013]
4. Karoui H, Hogg N, Fréjaville C, Tordo P and Kalyanaraman B. Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies. J. Biol. Chem. 1996; 271 (11): 6000-9. [DOI:10.1074/jbc.271.11.6000]
5. Dröge W. Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants. Exp. Gerontol 2002; 37 (12): 1333-45. [DOI:10.1016/S0531-5565(02)00175-4]
6. Smith AR, Shenvi SV, Widlansky M, Suh JH and Hagen TM. Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress. Curr. Med. Chem. 2004; 11 (9): 1135-46. [DOI:10.2174/0929867043365387]
7. Navari-Izzo F, Quartacci MF and Sgherri C. Lipoic acid: a unique antioxidant in the detoxification of activated oxygen species. Plant Physiol. Biochem. 2002; 40 (6-8): 463-70. [DOI:10.1016/S0981-9428(02)01407-9]
8. Rahimi R, Nikfar S, Larijani B and Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed. Pharmacother. 2005; 59 (7): 365-73. [DOI:10.1016/j.biopha.2005.07.002]
9. Cheng W, Fu YX, Porres JM, Ross DA and Lei XG. Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and protein. FASEB J. 1999; 13 (11): 1467-75. [DOI:10.1096/fasebj.13.11.1467]
10. Beck MA, Esworthy RS, Ho YS and Chu FF. Glutathione peroxidase protects mice from viral-induced myocarditis. FASEB J. 1998; 12 (12): 1143-9. [DOI:10.1096/fasebj.12.12.1143]
11. Spector A, Kuszak JR, Ma W, Wang RR, Ho Ys and Yang Y. The effect of photochemical stress upon the lenses of normal and glutathione peroxidase-1 knockout mice. Exp. Eye. Res. 1998; 67 (4): 457-71. [DOI:10.1006/exer.1998.0548]
12. Jaeschke H, Ho YS, Fisher MA, Lawson JA and Farhood A. Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress. Hepatology 1999; 29 (2): 443-50. [DOI:10.1002/hep.510290222]
13. Peterson J, Dwyer J, Adlercreutz H, Scalbert A, Jacques P and McCullough ML. Dietary lignans: physiology and potential for cardiovascular disease risk reduction. Nutr. Rev. 2010; 68 (10): 571-603. [DOI:10.1111/j.1753-4887.2010.00319.x]
14. Moghaddam MHB, Aghdam FB, Jafarabadi MA, Allahverdipour H, Nikookheslat SD and Safarpour S. The Iranian version of international physical activity questionnaire (IPAQ) in Iran: content and construct validity, factor structure, internal consistency and stability. World Appl. Sci. J. 2012; 18 (8): 1073-80.
15. Lee AS, Lee YJ, Lee SM, Yoon JJ, Kim JS, Kang DG and et al. Portulaca oleracea ameliorates diabeticvascular inflammation and endothelial dysfunction in mice. Evid Based Complement. Alternat. Med. 2012; 2012: 741824.
16. EI-Sayed MI. Effects of Portulaca oleracea L. Seeds in treatment of type-2 diabetes mellitus patients as adjunctive and alternative therapy. J. Ethnopharmacol. 2011; 137 (1): 643-51. [DOI:10.1016/j.jep.2011.06.020]
17. Laitiff AA, Teoh SL and Das S. Wound healing in diabetes mellitus: traditional treatment modalities. Clin. Ter. 2010; 161 (4): 359-64.
18. Agha-Hosseini F, Borhan-Mojabi K, Monsef-Esfahani H, Mirzaii-Dizgah I, Etemad-Moghadam SH and Karagah A. Efficacy of purslane in the treatment of oral lichen planus. Phytother. Res. 2010; 24 (2): 240-44. [DOI:10.1002/ptr.2919]
19. Ghorbanian B, Nourazarian M and Saberi Y. The effect of one period of progressive resistance training on plasma levels of omentin-1, insulin resistance, non-high density lipoprotein and some cardiovascular risk factors in men. Qom Univ. Med. Sci. J. 2017; 11 (2): 94-103.
20. Goldhammer E, Ben-Sira D, Zaid G, Biniamini Y, Maor I, Lanir A and et al. Paraoxonase activity following exercise-based cardiacrehabilitation program. J. Cardiopulm. Rehabil. Prev. 2007; 27 (3): 151-4. [DOI:10.1097/01.HCR.0000270691.09258.b1]
21. Modir M, Daryanoosh F, Tanideh N, Mohamadi M and Firouzmand H. The effects of short and middle times aerobic exercise with high intensities on ingredients antioxidant in female Sprague Dawley rats. Medical Journal of Mashhad University of Medical Sciences 2014 Jul-Aug; 57 (3): 587-595 .
22. Dĺaz- Castro J, Guisado R, Kajarabille N, Garacia C, Guisado I, Teresa C and et al. Coenzyme Q10 supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. Eur. J. Nutr. 2011; DOI 10.1007/s00394-011-0257-5. [DOI:10.1007/s00394-011-0257-5]
23. Pinho RA, Andrades ME, Oliveira MR, Pirola AC, Zago MS, Silveira PC, Dal-Pizzol F, Moreira JC. Imbalance in SOD/CAT activities in rat skeletal muscles submitted to treadmill training exercise. Cell Biol. International 2006; 30: 848-853. [DOI:10.1016/j.cellbi.2006.03.011]
24. Dong CX, Hayashi K, Lee JB and Hayashi T. Characterization of structures and antiviral effect olysaccharides from Portulaca oleracea L. Chem. Pharm. Bull. 2010; 58 (4): 507-10. [DOI:10.1248/cpb.58.507]
25. Chen CJ, Wang WY, Wang XL, Dong LW, Yue YT, Xin HL and et al. Anti-hypoxic activity of the ethanol extract from Portulaca oleracea in mice. J. Ethnopharmacol. 2009; 124 (2): 246-50. [DOI:10.1016/j.jep.2009.04.028]
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