year 18, Issue 72 (11-2019)
J. Med. Plants 2019, 18(72): 23-45 |
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Abdollahi E, Khodaparast M, Kiashi F, Hoormand M. Role of Medicinal Herbs in the Development of Renal Adverse Effects: A Review Study. J. Med. Plants 2019; 18 (72) :23-45
URL: http://jmp.ir/article-1-2701-en.html
URL: http://jmp.ir/article-1-2701-en.html
1- Department of Pharmacology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
2- Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran
3- Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Pharmacology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran ,hoormand.m@iums.ac.ir
2- Faculty of Pharmacy, Pharmaceutical Sciences Branch, Islamic Azad University (IAUPS), Tehran, Iran
3- Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Pharmacology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran ,
Abstract: (5857 Views)
The use of herbal medicines dates back to the beginning of the human history. Today, herbal medicines still play a significant role in the prevention and treatment of disease in many cultures and communities. There are few reports about adverse effects of herbal medicines. This is why many people around the world believe that herbal medicines can't cause adverse effects. They believe plants are safe, even if they're not efficient. This idea is wrong, regardless of how common it might be considered. Plants can be dangerous and even lethal in some cases. It is not just plant chemicals that might cause adverse effects. The role of environmental pollutants and the presence of fraud in form of alternation and adulteration in herbal preparations is another factor that might contribute to harmful effects on various organs of the body, including the kidneys. Kidneys are vital organs that filter blood, remove wastes and excrete the wastes in the urine. They are susceptible to injury because of their high exposure to different chemical substances including chemicals from the herbs. This is why studying the possible adverse effects of herbal medicines on kidney structure and function gets important. This issue highlights the role of regulatory and legislator organizations in providing up-to-date laws to help maintain a better regulation on the production and consumption of herbal products. This article reviews the findings on this case. We used papers published between 1990 and January 2018 in pubmed and google scholar databases.
Keywords: Adverse Drug Reactions, Drug adulteration, Environmental Pollutants, Herbal Medicines, Kidney
Type of Study: Review |
Subject:
Pharmacology & Toxicology
Received: 2018/04/13 | Accepted: 2019/02/3 | Published: 2019/10/28
Received: 2018/04/13 | Accepted: 2019/02/3 | Published: 2019/10/28
References
1. Ekor M. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Front Pharmacol. 2014; 10 (4): 177. doi: 10.3389/fphar.2013.00177. [DOI:10.3389/fphar.2013.00177]
2. Carmona F, Pereira AMS. Herbal medicines: old and new concepts, truths and misunderstandings. Revista Brasileira de Farmacognosia 2013; 23 (2): 379 - 85. [DOI:10.1590/S0102-695X2013005000018]
3. Jha V. Herbal medicines and chronic kidney disease. Nephrol. 2010; 15 (s2): 10 - 7. [DOI:10.1111/j.1440-1797.2010.01305.x]
4. Huxtable RJ. The harmful potential of herbal and other plant products. Drug Safety 1990; 5 (1): 126 - 36. [DOI:10.2165/00002018-199000051-00020]
5. Nauffal M and Gabardi S. Nephrotoxicity of natural products. Blood Purification 2016; 41 (1 - 3) 9 - 123. [DOI:10.1159/000441268]
6. Marcus DM, Grollman AP. Botanical medicines - the need for new regulations. N. Engl. J. Med. 2002; 347: 2073-2076. [DOI:10.1056/NEJMsb022858]
7. Luyckx VA and Naicker S. Acute kidney injury associated with the use of traditional medicines. Nature Reviews Nephrol. 2008; 4 (12): 664 - 671. [DOI:10.1038/ncpneph0970]
8. Parvaiz M, Hussain K, Khalid S, Hussnain N, Iram N, Hussain Z and et al. A review: Medicinal importance of Glycyrrhiza glabra L. (Fabaceae family). GJP. 2014; 8 (1): 8 - 13.
9. Singh NP and Prakash A. Nephrotoxic Potential of Herbal Drugs. JIMSA. 2011; 24 (2): 79-81.
10. zur Wiesch CS, Hahn K, Regier M, Sauer N, Beil F, Lebok P and et al. Hypertension with Hypokalemia in a Young Liquorice Addict. Ultrasound in Medicine & Biol. 2011; 37 (8): S4 - S5. [DOI:10.1016/j.ultrasmedbio.2011.05.045]
11. Inuzuka Y, Kishimori T, Inoue T, Seki J, Nishio S, Takeda S and et al. Sodium Restriction in Japanese Patients Hospitalized with Acute Decompensated Heart Failure. J. Cardiac Failure 2015; 21 (10): S183. [DOI:10.1016/j.cardfail.2015.08.214]
12. Dahl NV, editor Alternative Medicine and Nephrology Series Editor: Naomi V. Dahl: Herbs and Supplements in Dialysis Patients: Panacea or Poison? Seminars in dialysis; 2001, Wiley Online Library. [DOI:10.1046/j.1525-139X.2001.00051.x]
13. Luyckx VA. Nephrotoxicity of alternative medicine practice. Advances in Chronic Kidney Disease 2012; 19 (3): 129 - 41. [DOI:10.1053/j.ackd.2012.04.005]
14. Kamsu-Foguem B and Foguem C. Adverse drug reactions in some African herbal medicine: literature review and stakeholders' interview. IMR. 2014; 3 (3): 126 - 32. [DOI:10.1016/j.imr.2014.05.001]
15. Yasue H, Itoh T, Mizuno Y and Harada E. Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. Internal Medicine 2007; 46 (9): 575 - 8. [DOI:10.2169/internalmedicine.46.6316]
16. Clarke DR, Musa ARF, Fuelop T, Post-Parathyroidectomy State and Serum Albumin Levels in End-Stage Renal Disease Patients no Apparent Effect of Surgical Parathyrodectomy. Am. J. Kidney Dis. 2015; 65 (4): A1-A93. [DOI:10.1053/j.ajkd.2015.02.055]
17. Gabardi S, Munz K and Ulbricht C. A review of dietary supplement-induced renal dysfunction. CJASN. 2007; 2 (4): 757 - 65. [DOI:10.2215/CJN.00500107]
18. Bagnis CI, Deray G, Baumelou A, Le Quintrec M and Vanherweghem JL. Herbs and the kidney. AJKD. 2004; 44 (1): 1 - 11. [DOI:10.1053/j.ajkd.2004.02.009]
19. Wang X, Zhang H, Chen L, Shan L, Fan G and Gao X. Liquorice, a unique "guide drug" of traditional Chinese medicine: a review of its role in drug interactions. J. Ethnopharmacol. 2013; 150 (3): 781 - 90. [DOI:10.1016/j.jep.2013.09.055]
20. Hou Y-C, Lin S-P and Chao P-DL. Liquorice reduced cyclosporine bioavailability by activating P-glycoprotein and CYP 3A. Food Chem. 2012; 135 (4): 2307 - 12. [DOI:10.1016/j.foodchem.2012.07.061]
21. Mozafar SM. The Herbal Encyclopedia. 1st ed. Abej-Ebnesina-Andisheavar Press. Iran. 2016, pp: 1272-8. [in Persian].
22. Bennett S, Hoffman N and Monga M. Ephedrine and guaifenesin-induced nephrolithiasis. J. Alternative & Complementary Medicine 2004; 10 (6): 967 - 9. [DOI:10.1089/acm.2004.10.967]
23. Powell T, Hsu FF, Turk J and Hruska K. Ma-huang strikes again: ephedrine nephrolithiasis. AJKD. 1998; 32 (1): 153 - 9. [DOI:10.1053/ajkd.1998.v32.pm9669437]
24. Gabardi S, Cormier C, Cina J and Luyckx V. Renal dysfunction associated with herbal remedies and dietary supplements. Nephrology Rounds 2003; 2: 304 - 14.
25. Stahl CE, Borlongan CV, Szerlip H and Szerlip M. No pain, no gain: exercise-induced rhabdomyolysis associated with the performance enhancer herbal supplement ephedra. Medical Science Monitor 2006; 12 (9): CS81 - CS4.
26. Mozaffarian V. Indentification of Medicinal and Aromatic Plants of Iran. 1st ed. Moaser press. Tehran 2013, pp: 1-40. [in Persian].
27. Bora KS and Sharma A. The genus Artemisia: a comprehensive review. Pharmaceutical Biology. 2011; 49 (1): 101 - 9. [DOI:10.3109/13880209.2010.497815]
28. Nguyen HT and Németh ZÉ. Sources of variability of wormwood (Artemisia absinthium L.) essential oil. J. Applied Research on Medicinal and Aromatic Plants 2016; 3 (4): 143 - 50. [DOI:10.1016/j.jarmap.2016.07.005]
29. Lachenmeier DW, Emmert J, Kuballa T and Sartor G. Thujone-Cause of absinthism? Forensic science international. 2006; 158 (1): 1 - 8. [DOI:10.1016/j.forsciint.2005.04.010]
30. Weisbord SD, Soule JB and Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the Internet. NEJM. 1997; 337 (12): 825 - 7. [DOI:10.1056/NEJM199709183371205]
31. El Bazaoui A, Bellimam MA and Soulaymani A. Nine new tropane alkaloids from Datura stramonium L. identified by GC/MS. Fitoterapia 2011; 82 (2): 193 - 7. [DOI:10.1016/j.fitote.2010.09.010]
32. Trancă SD, Szabo R and Cociş M. Acute poisoning due to ingestion of Datura stramonium-a case report. Romanian J. Anaesthesia and Intensive Care 2017; 24 (1): 65. [DOI:10.21454/rjaic.7518.241.szb]
33. Disel NR, Yilmaz M, Kekec Z and Karanlik M. Poisoned after dinner: Dolma with datura stramonium. Turkish J. Emergency Medicine 2015; 5- 51: (1) 15. [DOI:10.5505/1304.7361.2015.70894]
34. Krenzelok EP. Aspects of Datura poisoning and treatment. Clinical Toxicol. 2010; 48 (2): 104 - 10. [DOI:10.3109/15563651003630672]
35. Günaydın YK, Yıldız CG, Işıkoğlu V, Kokulu K, Muraçar N, Akıllı NB and et al. Datura Stramonium Poisoning: Two Case Reports. Journal of Academic Emergency Medicine Case Reports/Akademik Acil Tip Olgu Sunumlari Dergisi (Acil Tip Uzmanlari Dernegi). 2017; 8 (1): 4-6. [DOI:10.5152/jemcr.2016.1471]
36. Arefi M, Barzegari N, Asgari M, Soltani S, Farhidnia N and Fallah F. Datura poisoning, clinical and laboratory findings. Report of five cases. Romanian J. Legal Medicine 2016; 24 (4): 308 - 11. [DOI:10.4323/rjlm.2016.308]
37. Dubey P and Sanjeev O. Acute Renal Failure: A Complication of Datura Poisoning. J. Kidney. 2017; 3 (147): 2472-1220.1000147.
38. Naqvi R. Acute kidney injury from different poisonous substances. World J. Nephrol. 2017; 6 (3): 162. [DOI:10.5527/wjn.v6.i3.162]
39. Suhail S, Shakir Jamil S, Jilani S and et al. Phytochemical and Pharmacological Review of Suranjan Shireen (Colchicum autumnale). Indo American Journal of Pharmaceutical Res. 2017; 7 (04): 8492 - 6.
40. Klintschar M, Beham-Schmidt C, Radner H, Henning G and Roll P. Colchicine poisoning by accidental ingestion of meadow saffron (Colchicum autumnale): pathological and medicolegal aspects. Forensic Science International. 1999; 106 (3): 191 - 200. [DOI:10.1016/S0379-0738(99)00191-7]
41. Brvar M, Ploj T, Kozelj G, Mozina M, Noc M and Bunc M. Case report: fatal poisoning with Colchicum autumnale. Critical Care. 2004; 8 (1): R56. [DOI:10.1186/cc2427]
42. Brnčić N, Višković I, Perić R, Đirlić A, Vitezić D and Cuculić D. Accidental plant poisoning with Colchicum autumnale: report of two cases. CMJ. 2001; 42 (6): 673 - 5.
43. Nagesh K, Menezes RG, Rastogi P, Naik N, Rasquinha JM, Senthilkumaran S and et al. Suicidal plant poisoning with Colchicum autumnale. J. Forensic and Legal Medicine 2011; 18 (6): 285 - 7. [DOI:10.1016/j.jflm.2011.04.008]
44. Wollersen H, Erdmann F, Risse M and Dettmeyer R. Accidental fatal ingestion of colchicine-containing leaves-toxicological and histological findings. Legal Medicine 2009; 11: S498 - S9. [DOI:10.1016/j.legalmed.2009.01.080]
45. Ryan M, Lazar I, Nadasdy GM, Nadasdy T and Satoskar AA. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clinical Nephrol. 2015; 83 (3): 177 - 83. [DOI:10.5414/CN108324]
46. Talasaz AH, Abbasi M-R, Abkhiz S and Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. NDT. 2010; 25 (11): 3792 - 3. [DOI:10.1093/ndt/gfq457]
47. Yagi S, El Tigani S and Adam S. Toxicity of Senna obtusifolia fresh and fermented leaves (kawal), Senna alata leaves and some products from Senna alata on rats. Phytotherapy Res. 1998; 12 (5): 324 - 30.
https://doi.org/10.1002/(SICI)1099-1573(199808)12:5<324::AID-PTR300>3.0.CO;2-2 [DOI:10.1002/(SICI)1099-1573(199808)12:53.0.CO;2-2]
48. Vanderperren B, Rizzo M, Angenot L, Haufroid V, Jadoul M and Hantson P. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Annals of Pharmacotherapy 2005; 39 (7 - 8): 1353 - 7. [DOI:10.1345/aph.1E670]
49. Cho BS, Kim SD, Choi YM and Kang HH. School urinalysis screening in Korea: Prevalence of chronic renal disease. Pediatr. Nephrol. 2001; 16: 1126-8. [DOI:10.1007/s004670100043]
50. Voss, D. Complementary medicines in predialysis patients. Nephrology 2005, 10: S201-S203. [DOI:10.1111/j.1440-1797.2005.00506_11.x]
51. Tewari I, Sood S and Gupta GL. Toxicities of herbal medicines: use with precautions. JPR. 2014; 4 (02).
52. Malik S, Cusidó RM, Mirjalili MH, Moyano E, Palazón J and Bonfill M. Production of the anticancer drug taxol in Taxus baccata suspension cultures: a review. Process Biochem. 2011; 46 (1): 23 - 34. [DOI:10.1016/j.procbio.2010.09.004]
53. Bandara V, Weinstein SA, White J and Eddleston M. A review of the natural history, toxinology, diagnosis and clinical management of Nerium oleander (common oleander) and Thevetia peruviana (yellow oleander) poisoning. Toxicon. 2010; 56 (3): 273 - 81. [DOI:10.1016/j.toxicon.2010.03.026]
54. Ardalan MR, Khodaie L, Nasri H and Jouyban A. Herbs and hazards: risk of aristolochic acid nephropathy in Iran. IJKD. 2015; 9 (1): 14 - 7.
55. Valerio LG and Gonzales GF. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and maca (Lepidium meyenii). Toxicological Reviews 2005; 24 (1): 11 - 35. [DOI:10.2165/00139709-200524010-00002]
56. Singh N and Prakash A. Herbal drugs and acute renal injury. Medicine Update 2008; 18: 150 - 5.
57. Combest W, Newton M, Combest A and Kosier JH. Effects of herbal supplements on the kidney. Urologic Nursing 2005; 25 (5): 381.
58. Hilepo JN, Bellucci AG and Mossey RT. Acute renal failure caused by 'cat's claw'herbal remedy in a patient with systemic lupus erythematosus. Nephron. 1997; 77 (3): 361. [DOI:10.1159/000190304]
59. Yakubu MT, Bilbis LS, Lawal M and Akanji MA. Evaluation of selected parameters of rat liver and kidney function following repeated administration of yohimbine. Biokemistri 2003; 15 (2): 50 - 6.
60. Eweka A, Om'Iniabohs F and Momodu O. The histological effects of mixed diet containing Pausinystalia yohimbe ground stem bark on the kidney of adult Wistar rats (Rattus norvegicus). Biol. Med. 2010; 2 (1): 30-36.
61. Bahekar A, Ingle R and Kendre V. Efficacy of fungicides and bioagent against fungal pathogens of Aloe vera. IJCS. 2017; 5 (4): 1540 - 3.
62. Agarwal N, Sadhukhan P, Saha S and Sil PC. Therapeutic Insights against oxidative stress induced diabetic nephropathy: a review. J. Autoimmune Disorders 2015; 1 (1). doi: 10.21767/2471-8513. [DOI:10.21767/2471-8513]
63. Ekor M. Nephrotoxicity and Nephroprotective Potential of African Medicinal Plants in: Kuete V. Toxicological Survey of African Medicinal Plants. Elsevier. 2014, pp: 357 - 93. [DOI:10.1016/B978-0-12-800018-2.00012-1]
64. Ramachandraiahgari Y, Madhavi R, Somesula SR, Adi PJ, Mannur IS, Enamala M and et al. Protective Role of Ethanolic Extract of Aloe vera Antioxidant Properties on Liver and Kidney of Streptozotocin-Induced Diabetic Rats. DJNB. 2012; 7 (1): 175-184.
65. Dangi N, Gyanwali M, Gyanwali P, Sapkota H, Pandey A and Shrestha A. Evaluation of aloe vera leaves extract in streptozotocin-induced diabetic nephropathy in rat. J. Chitwan Medical College 2017; 5 (4): 55 - 63. [DOI:10.3126/jcmc.v5i4.16555]
66. Kessler T, Jansen B and Hesse A. Effect of blackcurrant-, cranberry-and plum juice consumption on risk factors associated with kidney stone formation. European J. Clinical Nutrition 2002; 56 (10): 1020. [DOI:10.1038/sj.ejcn.1601442]
67. Gettman MT, Ogan K, Brinkley LJ, Adams-Huet B, Pak CY and Pearle MS. Effect of cranberry juice consumption on urinary stone risk factors. The Journal of Urology 2005; 174 (2): 590 - 4. [DOI:10.1097/01.ju.0000165168.68054.f8]
68. Vasas A, Orbán-Gyapai O and Hohmann J. The Genus Rumex: Review of traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 2015; 175: 198 - 228. [DOI:10.1016/j.jep.2015.09.001]
69. Islam R, Mamat Y, Ismayil I, Yan M, Kadir M, Abdugheny A and et al. Toxicity of anthraquinones: differential effects of rumex seed extracts on rat organ weights and biochemical and haematological parameters. Phytotherapy Res. 2015; 29 (5): 777 - 84. [DOI:10.1002/ptr.5317]
70. Zager RA. Rhabdomyolysis and myohemoglobinuric acute renal failure. Kidney International. 1996; 49 (2): 314 - 26. [DOI:10.1038/ki.1996.48]
71. Zimmerman JL and Shen MC. Rhabdomyolysis. Chest. 2013; 144 (3): 1058 - 65. [DOI:10.1378/chest.12-2016]
72. Vanholder R, Sever MS, Erek E and Lameire N. Rhabdomyolysis. JASN. 2000; 11 (8): 1553 - 61.
73. Vaziri ND, Thomas R, Sterling M, Seiff K, Pahl MV, Davila J and et al. Toxicity with intravenous injection of crude marijuana extract. Clinical Toxicol. 1981; 18 (3): 353 - 66. [DOI:10.3109/15563658108990042]
74. Brandenburg D and Wernick R. Intravenous marijuana syndrome. Western J. Medicine 1986; 145 (1): 94.
75. Bohatyrewicz M, Urasinska E, Rozanski J, Ciechanowski K. Membranous glomerulonephritis may be associated with heavy marijuana abuse. Transplant Proc. 2007; 39 (10): 3054-6. [DOI:10.1016/j.transproceed.2007.08.100]
76. Argamany JR, Reveles KR, Duhon B. Synthetic cannabinoid hyperemesis resulting in rhabdomyolysis and acute renal failure. The American J. Emergency Medicine 2016; 34 (4): 765. e1-. e2. [DOI:10.1016/j.ajem.2015.08.051]
77. Zhao A, Tan M, Maung A, Salifu M and Mallappallil M. Rhabdomyolysis and acute kidney injury requiring dialysis as a result of concomitant use of atypical neuroleptics and synthetic cannabinoids. Case Reports in Nephrol. 2015; 2015. [DOI:10.1155/2015/235982]
78. Durand D, Delgado LL, Parra-Pellot DMdl and Nichols-Vinueza D. Psychosis and severe rhabdomyolysis associated with synthetic cannabinoid use: a case report. Clinical Schizophrenia & Related Psychoses 2013; 8 (4): 205 - 8. [DOI:10.3371/CSRP.DUDE.031513]
79. Paul ABM, Simms L, Paul AE, Schmidseder C, Mahesan AA and Yorke J. Not safe for consumption: synthetic cannabinoids causing fatal acute rhabdomyolysis in two young men. IJCRI. 2016; 7 (7): 431 - 5. [DOI:10.5348/ijcri-201612-CS-10073]
80. Ulbricht C, Basch E, Szapary P, Hammerness P, Axentsev S, Boon H and et al. Guggul for hyperlipidemia: a review by the Natural Standard Research Collaboration. Complementary therapies in Medicine 2005; 13 (4): 279 - 90. [DOI:10.1016/j.ctim.2005.08.003]
81. Singh BB, Mishra LC, Vinjamury SP and Aquilina N. The effectiveness of Commiphora mukul for osteoarthritis of the knee: an outcomes study. Alternative Therapies in Health and Medicine 2003; 9 (3): 74.
82. Shen T, Li G-H, Wang X-N and Lou H-X. The genus Commiphora: a review of its traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 2012; 142 (2): 319 - 30. [DOI:10.1016/j.jep.2012.05.025]
83. Zhang X, Donnan PT, Bell S, Guthrie B. Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis. BMC nephrology. 2017;18(1):256. [DOI:10.1186/s12882-017-0673-8]
84. Brunton L, Knollman B and Hilal-Dandan R. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition: McGraw-Hill Education. 2017.
85. Papp I, Simándi B, Blazics B, Alberti Á, Héthelyi É, Szőke É and et al. Monitoring volatile and non-volatile salicylates in Filipendula ulmaria by different chromatographic techniques. Chromatographia 2008; 68 (1): 125 - 9. [DOI:10.1365/s10337-008-0749-5]
86. Blazics B, Papp I, Kéry Á. LC-MS qualitative analysis and simultaneous determination of six Filipendula salicylates with two standards. Chromatographia 2010; 71 (1): 61 - 7. [DOI:10.1365/s10337-010-1502-4]
87. Denev P, Kratchanova M, Ciz M, Lojek A, Vasicek O, Blazheva D and et al. Antioxidant, antimicrobial and neutrophil-modulating activities of herb extracts. Acta Biochimica Polonica 2014; 61 (2): 359-367. [DOI:10.18388/abp.2014_1907]
88. Harbourne N, Marete E, Jacquier JC and O'Riordan D. Effect of drying methods on the phenolic constituents of meadowsweet (Filipendula ulmaria) and willow (Salix alba). LWT-Food Science and Technol. 2009; 42 (9): 1468 - 73. [DOI:10.1016/j.lwt.2009.05.005]
89. Ali BH, Blunden G, Tanira MO and Nemmar A. Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): a review of recent research. Food and chemical Toxicol. 2008; 46 (2): 409 - 20. [DOI:10.1016/j.fct.2007.09.085]
90. Tjendraputra E, Tran VH, Liu-Brennan D, Roufogalis BD and Duke CC. Effect of ginger constituents and synthetic analogues on cyclooxygenase-2 enzyme in intact cells. Bioorganic Chem. 2001; 29 (3): 156 - 63. [DOI:10.1006/bioo.2001.1208]
91. Van Breemen RB, Tao Y and Li W. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia 2011; 82 (1): 38 - 43. [DOI:10.1016/j.fitote.2010.09.004]
92. Habib SHM, Makpol S, Hamid NAA, Das S, Ngah WZW and Yusof YAM. Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics. 2008; 63 (6): 807 - 13. [DOI:10.1590/S1807-59322008000600017]
93. Stoilova I, Krastanov A, Stoyanova A, Denev P, Gargova S. Antioxidant activity of a ginger extract (Zingiber officinale). Food Chem. 2007; 102 (3): 764 - 70. [DOI:10.1016/j.foodchem.2006.06.023]
94. Ramudu SK, Korivi M, Kesireddy N, Lee L-C, Cheng I-S, Kuo C-H and et al. Nephro-protective effects of a ginger extract on cytosolic and mitochondrial enzymes against streptozotocin (STZ)-induced diabetic complications in rats. Chin. J. Physiol. 2011; 54 (2): 79 - 86. [DOI:10.4077/CJP.2011.AMM006]
95. Almarshad HA, Tantawy AAE-H and Alenazi TA. The Nephroprotective Effect of Zingiber Officinale Extract against Azathioprine-Induced Renal Damage: An Experimental Histopathological Study. Aljouf University Medical J. 2015; 300 (3803): 1 - 8. [DOI:10.12816/0031453]
96. Ramudu SK, Korivi M, Kesireddy N, Chen C-Y, Kuo CH and Kesireddy SR. Ginger feeding protects against renal oxidative damage caused by alcohol consumption in rats. J. Renal Nutrition 2011; 21 (3): 263-70. [DOI:10.1053/j.jrn.2010.03.003]
97. Snow A, Halpenny D, McNeill G and Torreggiani WC. Life-threatening rupture of a renal angiomyolipoma in a patient taking over-the-counter horse chestnut seed extract. J. Emergency Medicine 2012; 43 (6): e401-e3. [DOI:10.1016/j.jemermed.2010.11.044]
98. Wang T, Jiang N, Han B, Liu W, Liu T, Fu Fand et al. Escin attenuates cerebral edema induced by acute omethoate poisoning. Toxicology Mechanisms and Methods 2011; 21 (5): 400-5. [DOI:10.3109/15376516.2010.550337]
99. Wang H, Zhang L, Jiang N, Wang Z, Chong Y and Fu F. Anti‑inflammatory effects of escin are correlated with the glucocorticoid receptor/NF‑κB signaling pathway, but not the COX/PGF2α signaling pathway. Experimental and Therapeutic Medicine 2013; 6 (2): 419-22. [DOI:10.3892/etm.2013.1128]
100. Li M, Lu C, Zhang L, Zhang J, Du Y, Duan S and et al. Oral administration of escin inhibits acute inflammation and reduces intestinal mucosal injury in animal models. Evidence-Based Complementary and Alternative Medicine 2015; 2015; doi: 10.1155/2015/503617. [DOI:10.1155/2015/503617]
101. Grasso A and Corvaglia E. Two cases of suspected toxic tubulonephrosis due to Escine. Gazz. Med. It. 1976; 135: 581-4.
102. Baibado JT and Cheung HY. Seed Extract of Horse Chestnut (Aesculus hippocastanum L.) as Effective Medication for Chronic Venous Insufficiency and Other Health Benefits. Hong Kong Pharmaceutical Journal 2010; 17(4): 156- 162.
103. Sur R, Martin K, Liebel F, Lyte P, Shapiro S and Southall M. Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium). Inflammopharmacol. 2009; 17 (1): 42-9. [DOI:10.1007/s10787-008-8040-9]
104. Smolinski AT and Pestka JJ. Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 (ginseng) and parthenolide (feverfew). Food and Chemical Toxicol. 2003; 41 (10): 1381-90. [DOI:10.1016/S0278-6915(03)00146-7]
105. Akram M, Shahab-Uddin AA, Usmanghani K, Hannan A, Mohiuddin E and Asif M. Curcuma longa and curcumin: a review article. Rom. J. Biol. Plant. Biol. 2010; 55 (2): 65-70.
106. Shishodia S, Potdar P, Gairola CG and Aggarwal BB. Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-κB activation through inhibition of IκBα kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 2003; 24 (7): 1269-79. [DOI:10.1093/carcin/bgg078]
107. Plummer SM, Holloway KA, Manson MM, Munks RJ, Kaptein A, Farrow S and et al. Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-κB activation via the NIK/IKK signalling complex. Oncogene. 1999; 18 (44): 6013. [DOI:10.1038/sj.onc.1202980]
108. Binion DG, Otterson MF and Rafiee P. Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. Gut. 2008; 57 (11): 1509-17. [DOI:10.1136/gut.2008.152496]
109. Lev-Ari S, Starr A, Vexler A, Karaush V, Loew V, Greif J and et al. Inhibition of pancreatic and lung adenocarcinoma cell survival by curcumin is associated with increased apoptosis, down-regulation of COX-2 and EGFR and inhibition of Erk1/2 activity. Anticancer Res. 2006; 26 (6B): 4423-30.
110. Chuncharunee A, Habuddha V and Chuncharunee A. Curcuma comosa ameliorates cisplatin-induced nephrotoxicity: COX-2 expression and ultrastructure changes. J. Medicinal Plants Res. 2016; 10 (34): 595-602. [DOI:10.5897/JMPR2016.6151]
111. Gayathri B, Manjula N, Vinaykumar K, Lakshmi B and Balakrishnan A. Pure compound from Boswellia serrata extract exhibits anti-inflammatory property in human PBMCs and mouse macrophages through inhibition of TNFα, IL-1β, NO and MAP kinases. International Immunopharmacol. 2007; 7 (4): 473-82. [DOI:10.1016/j.intimp.2006.12.003]
112. Singh D, Gupta R and Saraf SA. Herbs-are they safe enough? An overview. Critical Reviews in Food Science and Nutrition 2012; 52 (10): 876-98. [DOI:10.1080/10408398.2010.512426]
113. Balachandran P and Govindarajan R. Ayurvedic drug discovery. Expert Opinion on Drug Discovery 2007; 2 (12): 1631-52. [DOI:10.1517/17460441.2.12.1631]
114. Du Z, Liu Z, Ning Z, Liu Y, Song Z, Wang C and et al. Prospects of boswellic acids as potential pharmaceutics. Planta Medica 2015; 81 (04): 259-71. [DOI:10.1055/s-0034-1396313]
115. Nakagawa T and Yokozawa T. Direct scavenging of nitric oxide and superoxide by green tea. Food and Chemical Toxicol. 2002; 40 (12): 1745-50. [DOI:10.1016/S0278-6915(02)00169-2]
116. Yokozawa T, Noh JS and Park CH. Green tea polyphenols for the protection against renal damage caused by oxidative stress. Evidence-Based Complementary and Alternative Medicine. 2012; doi: 10.1155/2012/845917. [DOI:10.1155/2012/845917]
117. Crespy V and Williamson G. A review of the health effects of green tea catechins in in vivo animal models. The Journal of Nutrition 2004; 134 (12): 3431S-40S. [DOI:10.1093/jn/134.12.3431S]
118. Namita P, Mukesh R and Vijay KJ. Camellia sinensis (green tea): A review. Global J. Pharmacol. 2012; 6 (2): 52-9.
119. Moseley VR, Morris J, Knackstedt RW and Wargovich MJ. Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells. Anticancer Res. 2013; 33 (12): 5325-33.
120. Singh T and Katiyar SK. Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition. PLOS ONE 2011; 6 (10): e25224. [DOI:10.1371/journal.pone.0025224]
121. Ahmed S, Rahman A, Hasnain A, Lalonde M, Goldberg VM and Haqqi TM. Green tea polyphenol epigallocatechin-3-gallate inhibits the IL-1β-induced activity and expression of cyclooxygenase-2 and nitric oxide synthase-2 in human chondrocytes. Free Radical Biology and Medicine 2002; 33 (8): 1097-105. [DOI:10.1016/S0891-5849(02)01004-3]
122. Khan SA, Priyamvada S, Farooq N, Khan S, Khan MW and Yusufi AN. Protective effect of green tea extract on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney. Pharmacological Res. 2009; 59 (4): 254-62. [DOI:10.1016/j.phrs.2008.12.009]
123. Heinrich M, Chan J, Wanke S, Neinhuis C and Simmonds MS. Local uses of Aristolochia species and content of nephrotoxic aristolochic acid 1 and 2-a global assessment based on bibliographic sources. J. Ethnopharmacol. 2009; 125 (1): 108-44. [DOI:10.1016/j.jep.2009.05.028]
124. Asif M. A brief study of toxic effects of some medicinal herbs on kidney. Advanced Biomedical Res. 2012; 1: 44. [DOI:10.4103/2277-9175.100144]
125. Ferraro PM, Costanzi S, Naticchia A, Sturniolo A and Gambaro G. Low level exposure to cadmium increases the risk of chronic kidney disease: analysis of the NHANES 1999-2006. BMC Public Health 2010; 10 (1): 304. [DOI:10.1186/1471-2458-10-304]
126. Smitherman J and Harber P. A case of mistaken identity: herbal medicine as a cause of lead toxicity. American J. Industrial Medicine 1991; 20 (6): 795-8 [DOI:10.1002/ajim.4700200611]
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