year 9, Issue 35 (9-2010)
J. Med. Plants 2010, 9(35): 33-50 |
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Dehghan E, Hosseini B, Naghdi Badi H, Shahriari Ahmadi F. Application of Conventional and New Biotechnological Approaches for Improving of Morphinane Alkaloids Production. J. Med. Plants 2010; 9 (35) :33-50
URL: http://jmp.ir/article-1-264-en.html
URL: http://jmp.ir/article-1-264-en.html
1- Department of Biotechnology and Plant Breeding, Faculty of Agriculture, Ferdowsi University of Mashhad , es.dehghanshahreza@gmail.com
2- Department of Horticulture, Faculty of Agriculture, Urmia University
3- Iranian Academic Center for Education, Culture & Research (ACECR)
4- Department of Biotechnology and Plant Breeding, Faculty of Agriculture, Ferdowsi University of Mashhad
2- Department of Horticulture, Faculty of Agriculture, Urmia University
3- Iranian Academic Center for Education, Culture & Research (ACECR)
4- Department of Biotechnology and Plant Breeding, Faculty of Agriculture, Ferdowsi University of Mashhad
Abstract: (5580 Views)
More than 12,000 alkaloids are known in plants, mostly used as medicine with a world market value of about 4 billion US$. Opium poppy, Papaver somniferum, is the most important economic source of morphinane alkaloids such as morphine, codeine, thebaine, narcotine and papaverine that are exploited by the pharmaceutical industry as analgesics, antitussives and anti-spasmodics. With regard to increasing demand for these compounds, the aim of this review is presenting an outlook of classical breeding programs that successfully applied for enhancing the alkaloid content of opium poppy. The latest biotechnological approaches also are discussed to give an outlook for future trends and possibilities.
Keywords: <, i>, Papaver<, /i>, species, Biotechnological methods, Conventional breeding, Morphinane Alkaloids, Tissue culture, Metabolic engineering
Type of Study: Research |
Subject:
Pharmacognosy & Pharmaceutics
Received: 2010/04/4 | Accepted: 2010/08/30 | Published: 2010/10/29
Received: 2010/04/4 | Accepted: 2010/08/30 | Published: 2010/10/29
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