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:: Volume 4, Issue 40 (12-2011) ::
JMP 2011, 4(40): 17-25 Back to browse issues page
A Review on Pharmacological Effects of Ferula assa - foetida L.: a Systematic Review
AR Zare AR 1, M Omidi 2, H Fallah Hoseini 3, D Yazdani 4, Sh Rezazadeh 4, N Irvani * 5, A Oladzad 1
1- Department of Biotechnology, Institute of Medicinal Plants, ACECR
2- Department of Plant Breeding, University of Tehran
3- Department of Pharmacology and Applied Medicine, Institute of Medicinal Plants, ACECR
4- Department of Pharmocognosy, Institute of Medicinal Plants, ACECR
5- Department of Biotechnology, Faculty of New Technologies and Energy Engineering, Shahid Beheshti University , neda.irvani@gmail.com
Abstract:   (5403 Views)
Ferula assa - foetida L., commonly known as Asafetida is an herbaceous, monocarpic, perennial medicinal plant of the Apiaceae family. The main origin of Ferula assa - foetida is the steppes of Iran and Afghanistan. Asafetida gum-resin has a long history for food additive and medicinal uses. In Asian traditional medical systems Asafetida gum-resin has been expected to be used as digestive system, cleansing and strengthening the gastro-intestinal tract, anthelmintic, antispasmodic, carminative, expectorant, laxative, sedative and stomachic. Due to its current uses as well as its pharmacological effects further information needs for future clinical studies. The aim of this review was to provide an update overview of research studies focused on the pharmacological effects of Asafetida gum-resin. A computerized search of published articles was performed using the electronic database such as MEDLINE to 2010. The results indicate that, the large numbers of articles published on pharmacological effects of Asafetida over recent three decade. Asafetida gum-resin exert several pharmacological effects including, anti-histamine effect in gastero intestinal system, anti-oxidant, anti-cancer, anticholinergic, and hypoglycemic as observed in experimental and clinical studies. In conclusion the present scientific-based evidence provides good information about pharmacological effects of Asafetida gum-resin. This information may be useful to researcher for induction of clinical trial for this herbal medicine in treatment of traditionally recognized application such as gastrointestinal disease, cancer, hypertension and diabetes.
Keywords: Ferula assa - foetida, Medicinal plant, Traditional medicine, Pharmacological effects
Full-Text [PDF 177 kb]   (3472 Downloads)    
Type of Study: Review | Subject: Biotechnology
Received: 2014/10/11 | Accepted: 2014/10/11 | Published: 2014/10/11
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Zare AR A, Omidi M, Fallah Hoseini H, Yazdani D, Rezazadeh S, Irvani N et al . A Review on Pharmacological Effects of Ferula assa - foetida L.: a Systematic Review. JMP. 2011; 4 (40) :17-25
URL: http://jmp.ir/article-1-177-en.html

Volume 4, Issue 40 (12-2011) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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