year 5, Issue 18 (5-2006)                   J. Med. Plants 2006, 5(18): 1-10 | Back to browse issues page

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Yari Khosroshahi A, Habibi Khaniani B, Naghdi Badi H. Review on taxol as the most important anticancer natural drug. J. Med. Plants 2006; 5 (18) :1-10
1- Research Center for pharmaceutical Nanotechnology, Tabriz University of medical sciences, Tabriz, Iran
2- Institue of medicinal plants, Iranian Academic Center for Education, Culture, and Research (ACECR), Tehran, Iran ,
3- Institue of medicinal plants, Iranian Academic Center for Education, Culture, and Research (ACECR) & Tarbiat Modares University Tehran, Iran
Abstract:   (13907 Views)
Taxol is a diterpeniod with complex structure, which is extracted frequently from the genus Taxus. At present, this drug is one of the most important anticancer natural agents with different mechanism from other similar drugs, used for remedy of different cancers such as, melanoma, lung cancer, non-hodgkins lymphoma, meatus urinarius cancer, esophagus cancer, etc. At present, many scientists are trying total synthesis and semi-synthesis of taxol and also its extraction from cell culture. however, these methods have characteristic problems. The increasing demand of taxol for clinical use as an anticancer drug combined with limited supply from plant sources require a thorough understanding of its biosynthesis and extraction methods.
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Type of Study: Review | Subject: Medicinal Plants
Received: 2005/07/19 | Accepted: 2005/12/15 | Published: 2006/06/21

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