year 5, Issue 20 (12-2006)                   J. Med. Plants 2006, 5(20): 1-10 | Back to browse issues page

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Sharafi A, Hashemi Sohi H, Kazemi Tabar K. Overview on Tissue Culture, Regeneration and Gene Transfornation to Artemisia annua L.. J. Med. Plants 2006; 5 (20) :1-10
URL: http://jmp.ir/article-1-645-en.html
1- National Institute for Genetic Engineering and Biotechnology, Tehran, Iran
2- National Institute for Genetic Engineering and Biotechnology, Tehran, Iran , hashemi@nrcgeb.ac.ir
3- Biotechnology Group, Mazandaran University, Mazandaran, Iran
Abstract:   (5981 Views)
Artemisia annua L. a highly aromatic annual herb is a widely dispersed through out the temperate region containing the main active anti malaria compound artemisinin a sesquiterpene lactone. Because of low artemisinin level, unsuccessful chemical synthesis and slightly improvement of molecular breeding methods, biosynthesis of this valuable compound was noticed by using the tissue culture and Genetic Engineering in these years. The rate transformation could be varies with different factors like genotype, age, explant type and agrobacterium strain. The results recently was shown that explants in tissue cultures are very sensitive to kanamycin concentration and even it could be late shoot and root forrnation. Hairy root culture is another subject that is in these years was niticed as a alternative method by designing the new bioreactor for production if this secondrary metabolite.
Full-Text [PDF 382 kb]   (7094 Downloads)    
Type of Study: Review | Subject: Biotechnology
Received: 2006/09/3 | Accepted: 2006/12/16 | Published: 2007/01/21

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