[Home ] [Archive]   [ فارسی ]  
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 1, Issue 21 (3-2007) ::
J. Med. Plants 2007, 1(21): 20-25 Back to browse issues page
Evaluation of Antioxidant Activity of Methanolic Extracts and some Fractions of Salvia verticillata L. Using Three Different Methods
E Souri *1, H Farsam2, S Ardestani3, M Zolfagharifar2
1- 1- Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran , souri@sina.tums.ac.ir
2- 1- Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
3- Razi Institute For Drug Research, Iran University For Medical Science’Tehran, Tehran, Iran
Abstract:   (5584 Views)
Background: Bradykinin has effects on histaminic response,vessels seepage,cellular reproduction,causing fever, pain and coughs caused by ACE controllers (3,4,6). Noscapin has controlled Bradykinins contractional effects on guinea pigs trachea and rats vazodofran (5,6). noscapin stops the secondary effects of eskimi in brains edema, with antagonizing the responses caused by Bradykinin (3,4,8). Objective: considering that opium’s alkaloids act as agonist of peptide systems like ankephalins and RAS, its interesting to know the effects of this alkaloids and among them Noscapine on B3 Bradykinin receptors on smooth muscle guinea pig trachea? Method: All variables are reported as mean and standard deviation.We have used pair test and the informations were processed by Excel, Statistical analysis with ANOVA (LSD) SPSS 9. Results: we took diagrams in to consideration and indicated that the contract ional effect of Bradykinin decreased dependent on density, in presence of three different amount of noscapines concentration. In this study we could demonstrate that noscapine interact with Bradykenin as a non competitive antagonist.
Keywords: Bradykenin, Histamine, Noscapine, Indometacine
Full-Text [PDF 246 kb]   (909 Downloads)    
Type of Study: Research | Subject: Medicinal Chemistry
Received: 2014/12/1 | Accepted: 2014/12/1 | Published: 2014/12/1
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Souri E, Farsam H, Ardestani S, Zolfagharifar M. Evaluation of Antioxidant Activity of Methanolic Extracts and some Fractions of Salvia verticillata L. Using Three Different Methods. J. Med. Plants. 2007; 1 (21) :20-25
URL: http://jmp.ir/article-1-637-en.html


Volume 1, Issue 21 (3-2007) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 3991