year 6, Issue 23 (9-2007)                   J. Med. Plants 2007, 6(23): 72-79 | Back to browse issues page

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Ahmadi-Avval P, Mojab F, Noujavan S. Quantitation of Δ7-Sterols in Seeds Oil of Cucurbita pepo. J. Med. Plants 2007; 6 (23) :72-79
1- Iranian Academic Center for Education, Culture and Research (ACECR), Shahid Beheshty Branch, Tehran, Iran ,
2- Pharmaceutical Sciences Research Center (PSRC), Shahid Beheshty Medical Sciences (SBMU), Tehran, Iran
3- Iranian Academic Center for Education, Culture and Research (ACECR), Shahid Beheshty Branch, Tehran, Iran
Abstract:   (5030 Views)
Background: One of the famous medicinal plants is Cucurbita pepo (Cucurbitaceae), which its seeds used as diuretic and anthelminthic. Recently, the seeds have used as symptomatic relief of Benign Prostate Hyperplasia. It is said, seeds’ steroids are responsible for these effects. Objectives: This research was performed for identification and quantitation of sterols in Cucurbita pepo cultivated in Iran and comparison those of Hungarian origin. Methods: Seeds oil was extracted by Soxhelet apparatus with methylene chloride. Peponene (soft gel capsule of pumpkin oil) was purchased from Hungary. Derivatization of standard sterols and oils were performed by hexamethyl disilasane and trimethyl chlorosilane and samples were injected to GC/MS. Results and Conclusion: Analysis of the Hungarian pumpkin oil shows three sterols, campestrol (0.82), stigmasterol (0.78) and avanestrol (0.84 mg/g oil). Analysis of the Iranian pumpkin oil shows campestrol (0.38) and stigmasterol (0.67 mg/g oil), and avanestrol is absent. l
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Type of Study: Research | Subject: Pharmacognosy & Pharmaceutics
Received: 2005/11/5 | Accepted: 2006/12/20 | Published: 2007/09/22

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