year 6, Issue 24 (12-2007)
J. Med. Plants 2007, 6(24): 58-63 |
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Soleimani S, Bernard F, Amini M, Khavari- nezhad R. Alkaloids from NNarcissus tazetta L.. J. Med. Plants 2007; 6 (24) :58-63
URL: http://jmp.ir/article-1-555-en.html
URL: http://jmp.ir/article-1-555-en.html
1- Department of Plant Biology, Islamic Azad University, Science and Research Branch, Tehran, Iran , moho_plant@yahoo.com
2- Department of Biology, Faculty of Science, Shaheed Beheshti University, Tehran, Iran
3- Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Plant Biology, Islamic Azad University, Science and Research Branch, Tehran, Iran
2- Department of Biology, Faculty of Science, Shaheed Beheshti University, Tehran, Iran
3- Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4- Department of Plant Biology, Islamic Azad University, Science and Research Branch, Tehran, Iran
Abstract: (6632 Views)
Background: Narcissus tazetta of the Amaryllidaceae is a monocotyledon, perennial and bulbous plant. This ornamental fragrant plant has various alkaloids that have shown anti tumor, anti virus and anticholinergic activities. Objective: In this study, we have investigated the alkaloids of the bulbs of Narcissus tazetta (post flowering) from Gilan province, north of Iran. Methods: Ethanolic extract of bulbs were prepared. Then the alkaloids were extracted with different solvents (Et2O, CHCl3, Na2CO3 solution) to yielding a brown gum. This extract was Done chromatography by TLC on silica gel. The separated alkaloids were identified by the study of their NMR, IR and MASS spectra. Results: The bulbs of Narcissus tazetta from Gilan province were found to contain homolycorine as the major alkaloid as well as tazettine and ismine. Conclusion: This is the first report of ismine identification in the N. tazetta whereas tazettine and demethylated derivative of homolycorine, that have medicinal properties, were found previously.
Type of Study: Research |
Subject:
Pharmacology & Toxicology
Received: 2006/08/30 | Accepted: 2007/09/15 | Published: 2007/12/21
Received: 2006/08/30 | Accepted: 2007/09/15 | Published: 2007/12/21
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