year 24, Issue 96 (12-2025)
J. Med. Plants 2025, 24(96): 68-82 |
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Nguyen T B T, Tran Thanh M, Huynh L H, Cao L N H. The essential oil of Alpinia officinarum Hance: chemical compounds, antioxidant, antimicrobial, and anti-inflammatory activities. J. Med. Plants 2025; 24 (96) :68-82
URL: http://jmp.ir/article-1-3954-en.html
URL: http://jmp.ir/article-1-3954-en.html
1- Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam , ntbthuyen@ctu.edu.vn
2- Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
3- Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
2- Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
3- Faculty of Chemical Engineering, Can Tho University, Campus II, 3/2 Street, Ninh Kieu District, Can Tho City, Vietnam
Abstract: (415 Views)
Background: Alpinia officinarum Hance (A. officinarum) roots are used as a treatment for various illnesses, including colds, stomachaches, inflammation, and discomfort. Objective: This work aimed to evaluate the anatomy, chemical compounds, antioxidant, antimicrobial, and anti-inflammatory activities of A. officinarum roots essential oil (EO). Methods: First, the plant's anatomy was studied by the alum-green iodine staining 0method, followed by steam distillation to extract EOs. The determination of chemical compositions by Gas chromatography-mass spectroscopy (GC-MS). The antioxidant activities were conducted by free radical resistance by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ABTS (2,2-Azino-bis-3-ethylbenzothiazoline-6-sulphonic acid), and FRAP (Ferric Reducing Antioxidant Power). The paper plate method was used to determine antimicrobial activity. Finally, the anti-denaturation of the Bovine serum albumin assay was measured for the anti-inflammatory properties of EO. Results: Anatomical results show that the EO of A. officinarum is distributed in the form of secretory sacs. By GC-MS, twenty-eight components were identified; the main compounds are Eucalyptol (24.57 %), β-Bisabolene (9.72 %), and β-Sesquiphellandrene (5.95 %). The IC50 of FRAP, ABTS, and DPPH assays are 810.00 µg/mL, 1343.71 µg/mL, and 26953.21 µg/mL, respectively. In addition, the EO exhibited anti-inflammatory activity with an IC50 of 2.55 mg/mL, compared to the standard Diclofenac (1.03 mg/mL). Additionally, the antimicrobial activity test demonstrated that the EO exhibited antimicrobial activity against various bacterial strains, including Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Staphylococcus aureus, Bacillus cereus, and Listeria innocua. Conclusions: These findings demonstrate that EOs can be utilized in the production of anti-inflammatory compounds and ferric-reducing additives.
Type of Study: Research |
Subject:
Medicinal Plants
Received: 2025/07/15 | Accepted: 2025/11/25 | Published: 2025/12/1
Received: 2025/07/15 | Accepted: 2025/11/25 | Published: 2025/12/1
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