year 18, Issue 72 (11-2019)
J. Med. Plants 2019, 18(72): 170-182 |
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Ebrahimzadeh Zgemi S, Golmakani N, Asili M, Naseri A, Mohebbi Dehnavi Z, Kamali Z et al . A Comparative Study on the Effect of Artemisia and Clotrimazole Vaginal Cream on Vaginal Candida Infection on Non-Pregnant Women in Fertile Age in Mashhad in 2016-2017: A Triple Blind Clinical Trial. J. Med. Plants 2019; 18 (72) :170-182
URL: http://jmp.ir/article-1-2714-en.html
URL: http://jmp.ir/article-1-2714-en.html
S Ebrahimzadeh Zgemi1 
, N Golmakani2 , MJ Asili3 , A Naseri4 , Z Mohebbi Dehnavi5 , Z Kamali6 , A Saber Mohammad * 7
, N Golmakani2 , MJ Asili3 , A Naseri4 , Z Mohebbi Dehnavi5 , Z Kamali6 , A Saber Mohammad * 7
1- PhD student in Reproductive Health, Faculty member of midwifery, Department of Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
2- Assistant professor of Midwifery, Faculty Member of Mashhad University of Medical Sciences, Department of midwifery, Mashhad, Iran
3- Assistant professor of Pharmacy, Faculty member of Mashhad University of Medical Sciences, Department of Pharmacy, Mashhad, Iran
4- Assistant professor of Parasitology & Mycology, Faculty member of Mashhad University of Medical Sciences, Department of Parasitology & Mycology, Mashhad, Iran
5- Master of Midwifery, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
6- Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
7- Master of Midwifery, Department of Midwifery, Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran ,saberma921@mums.ac.ir
2- Assistant professor of Midwifery, Faculty Member of Mashhad University of Medical Sciences, Department of midwifery, Mashhad, Iran
3- Assistant professor of Pharmacy, Faculty member of Mashhad University of Medical Sciences, Department of Pharmacy, Mashhad, Iran
4- Assistant professor of Parasitology & Mycology, Faculty member of Mashhad University of Medical Sciences, Department of Parasitology & Mycology, Mashhad, Iran
5- Master of Midwifery, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
6- Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran
7- Master of Midwifery, Department of Midwifery, Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran ,
Abstract: (4257 Views)
Background: About 75% of women experience at least one vulvovaginal candidiasis during their life. Clotrimazole is an antifungal drug that has side effects along with its therapeutic properties. For this reason, a large percentage of women tend to use natural herbal treatments. Artemisia is an anti-fungal activity.
Objective: The aim of this study was to compare the effect of Artemisia vulgaris and Clotrimazole on vaginal candida infection on non pregnant women in fertility ages.
Methods: This study is a triple blind clinical trial performed on 72 non-pregnant women in Mashhad in 2016-2017 years. The research units were divided into two groups (receiving Artemisia Vaginal Cream and receiving Clotrimazole Vaginal Cream). After confirmation of candidacy and having consent for participation, by random allocation and treated for seven nights. After the treatment, the data was analyzed using SPSS software (version 24).
Results: After treatment, the score for candidate vaginal symptoms was not significant in Artemisia and Clotrimazole group based on Mann-Whitney test (P = 0.518). The Wilcoxon test showed a significant reduction in the symptoms of vaginal candida infection before and after treatment in both groups of Artemisia (P <0.001) and clotrimazole (P <0.001).
Conclusion: Due to the similar effects of Artemisia and Cholitrimazole, Artemisia can be used as an alternative treatment for vaginal candidiasis due to less side effects.
Objective: The aim of this study was to compare the effect of Artemisia vulgaris and Clotrimazole on vaginal candida infection on non pregnant women in fertility ages.
Methods: This study is a triple blind clinical trial performed on 72 non-pregnant women in Mashhad in 2016-2017 years. The research units were divided into two groups (receiving Artemisia Vaginal Cream and receiving Clotrimazole Vaginal Cream). After confirmation of candidacy and having consent for participation, by random allocation and treated for seven nights. After the treatment, the data was analyzed using SPSS software (version 24).
Results: After treatment, the score for candidate vaginal symptoms was not significant in Artemisia and Clotrimazole group based on Mann-Whitney test (P = 0.518). The Wilcoxon test showed a significant reduction in the symptoms of vaginal candida infection before and after treatment in both groups of Artemisia (P <0.001) and clotrimazole (P <0.001).
Conclusion: Due to the similar effects of Artemisia and Cholitrimazole, Artemisia can be used as an alternative treatment for vaginal candidiasis due to less side effects.
Type of Study: Research |
Subject:
Pharmacology & Toxicology
Received: 2017/12/22 | Accepted: 2018/08/26 | Published: 2019/10/28
Received: 2017/12/22 | Accepted: 2018/08/26 | Published: 2019/10/28
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