Khaki A, Fathiazad F, Ahmadi - Ashtiani H, Rastegar H, Imani A, Khaki A et al . Evaluation of
Ocimum basilicum Effects on Uterus Apoptosis in Rats Exposures in Electromagnetic Fields. J. Med. Plants 2010; 9 (36) :155-160
URL:
http://jmp.ir/article-1-258-en.html
1- Departement of Anatomical Sciences, Islamic Azad University
2- Department of Pharmacognosy, Tabriz University of Medical Sciences
3- Biochemistry and Nutrition Department of Zanjan Medical University, Zanjan, Iran & PhD student of Clinical Biochemistry, School of Medical Science, Tarbiat Modarres University
4- Ministry of Health and Medical Education, Food & Drug Laboratory Research Center
5- Department of Vet Pathology, Young Researcher Club, Islamic Azad University, Tabriz Branch
6- Department of Vet Pathology, Islamic Azad University , arashkhaki@yahoo.com
7- Institute of Medicinal Plants, ACECR
Abstract: (6628 Views)
Background: In the industrial world, almost everyone is unavoidably exposed to ambient electromagnetic field (EMF) generated from various technical and household appliances. Objective: Controversy exists about the effects of EMF on various tissues of the living bodies. Uterus play an important role in reproductive and the effects of EMF on its tissue is worthy of investigation. Methods: In order to examine this, 40 rat were selected and kept for one weeks in quarantine and 20 rats subdivided to two groups were exposed to 50 Hz (non-ionizing radiation) for 6 weeks, one of this exposed group received 0.7 g/kg Ocimum basilicum, other experimental group just received 0.7 g/kg Ocimum basilicum, The materials were processed and observed apoptosis under a light microscope. Results: In the experimental rats apoptotic cells showed significantly increased in emf groups, but in exposed group that received Ocimum basilicum ,apoptotic cells were decreased (p<0.05). Conclusion: As exposure to EMF may result in pathological changes then lead to sub fertility and infertility, Since in our study 0.7 g/kg Ocimum basilicum have significantly Preventive effect on uterus cells damages by reducing number of Apoptotic cells, so it seems that using it can be effective for treatment in emf exposed Rat.
Type of Study:
Research |
Subject:
Pharmacology & Toxicology Received: 2009/12/26 | Accepted: 2010/11/11 | Published: 2010/12/21