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:: Volume 4, Number 36 (12-2010) ::
JMP 2010, 4(36): 66-71 Back to browse issues page
Antifungal Activity of Cinnamomum zeylanicum Essential Oil Against Clinical Isolates of Aspegillus
R Mohammadi *1, MR Shokooh Amiri2, SM Mousavi2, A Sepahvand2, M Shams Ghahferokhi3, MH Yadegai3, Sh Roudbar Mohammadi3, Sh Shadzi4
1- (Ph.D. student) Medical Mycology, Tarbiat Modares University , Dr.Rasoul_mohammadi@yahoo.com
2- (Ph.D. student) Medical Mycology, Tarbiat Modares University
3- (Ph.D.) Medical Mycology, Tarbiat Modares University
4- (Ph.D.) Medical Mycology, Esfahan University of Medical sciences
Abstract:   (2393 Views)
Background: Aspergillosis is an opportunistic fungal disease caused by different species of Aspergillus. Clinical manifestation and severity of disease related to physiological conditions of host, involved organs and Aspergillus species. Cinnamomum zeylanicum is an evergreen tree 10-15 meter length and belongs to Lauraceae family. It grows in Srilanka. Its essential oil has antimicrobial activity. Objective: Study of Antifungal activity of this essential oil against clinical isolates of Aspergillus and determination of MIC. Methods: Broth microdilution method was used in this research .Essential oil of Cinnamomum zeylanicum was extracted by means of Clevenger apparatus then its MICs on clinical isolates of Aspergillus were calculated by broth microdilution method. Results: Number of samples was twenty seven. MICs are: eight isolates: 1.18 μg/ml, six isolates: 0.59 μg/ml, four isolates: 0.29 μg/ml, five isolates: 0.14 μg/ml and four isolates: 0.07μg/ml Conclusion: In view of the fact that Cinnamomum zeylanicum essential oil was effective against all isolates in this research, we recommend the investigation of its antifungal properties Invivo.
Keywords: Cinnamomum zeylanicum, Aspergillus, Antifungal activity, Essential oil
Full-Text [PDF 275 kb]   (766 Downloads)    
Type of Study: Research | Subject: Mycology
Received: 2014/10/19 | Accepted: 2014/10/19 | Published: 2014/10/19
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Mohammadi R, Shokooh Amiri M, Mousavi S, Sepahvand A, Shams Ghahferokhi M, Yadegai M, et al . Antifungal Activity of Cinnamomum zeylanicum Essential Oil Against Clinical Isolates of Aspegillus. JMP. 2010; 4 (36) :66-71
URL: http://jmp.ir/article-1-247-en.html
Volume 4, Number 36 (12-2010) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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