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:: Volume 2, Issue 38 (10-2011) ::
J. Med. Plants 2011, 2(38): 95-101 Back to browse issues page
To Investigate the Effect of Portulaca oleracea L. and Melissa officinalis L. Extract on Sleeping Time in Mice
H Miladi - Gorji *1, AA Vafaei2, A Bageri3
1- Department and Physiology Research Center, Semnan University of Medical Sciences , miladi331@yahoo.com
2- Department and Physiology Research Center, Semnan University of Medical Sciences
3- Faculty of Medicine, Semnan University of Medical Sciences Semnan
Abstract:   (4849 Views)
Background: Portulaca oleracea (PO) and Melissa officinalis (MO) overgrow in the different parts of Iran. In previous studies, systemic administration of the extract of PO and MO induces antinociceptive, anxiolytic and anticonvulsive, sedative effects in animals. Objective: This study was designed to evaluate different doses of the aqueous decoction extracts of PO and MO on sleeping time on mice. Methods: Male albino mice (25 - 30 g) were used in this study. The animals divided to control (saline), PO (25, 50 and 75 mg/kg) and MO (5, 10 and 25 mg/kg) groups (by IP injection). For measuring of sleeping time we used Angle method. Results: The results have shown that three doses of PO and two doses of 10 and 25 MO significantly increased sleeping time (p=0.000). Conclusion: This finding showed that PO and MO may be play important role on the modulation of sleeping time.
Keywords: Aqueous decoction extracts, Portulaca oleracea, Melissa officinalis, Sleeping time
Full-Text [PDF 189 kb]   (1443 Downloads)    
Type of Study: Research | Subject: Physiology
Received: 2014/10/15 | Accepted: 2014/10/15 | Published: 2014/10/15
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Miladi - Gorji H, Vafaei A, Bageri A. To Investigate the Effect of Portulaca oleracea L. and Melissa officinalis L. Extract on Sleeping Time in Mice. J. Med. Plants. 2011; 2 (38) :95-101
URL: http://jmp.ir/article-1-216-en.html


Volume 2, Issue 38 (10-2011) Back to browse issues page
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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