Objective: Turmeric (Curcuma longa L.) has protective effects on Liver and digestive system. Based on the importance of poultry industry and toxic agents that induce disease in broilers, we studied the protective effect of Turmeric on liver. Methods: Pre treatment with turmeric (1 mg/KgB.W) for 14 days and treatment with acetaminophen (650 mg/kgB. W) and turmeric for 30 days were conducted. Determination of daily body weight gain and hystopathological studies on liver, smallintestine and forestomach were conducted. Results: pre treatment with turmeric resulted in better rate of growth and improvement of small intestine mocus. The side effect of acetaminophen was reversed after treatment with the extract. Conclusion: it is suggested that addition of Turmeric to poultry nutrient is very useful for protection against toxins. That reffers to curcumin.