Drug addiction is destructive misfortune. At the present time we have over 1.2 million addicted people in Iran. So, proper and definite treatment must be noticed. Using the medical plants in ancientness like human life and thousand documents in medicinal history have valuable informations and expriments in this field. According to extant investigations, Trachyspermum copticum has numerous effects, such as antiseptic, expectorant, Spasm relaxation and useful in cholesteralemia. But in the belief of Iranian people, this plant is used for treatment of addiction. This project is the first investigation in the world that Iranian researchers evaluated the effect of trachyspermum copticum extract in treatment of morphine dependency. After preparing the trachyspermum copticum fruit from height of the mountain in KHozestan (between izeah and dehdaz), aqueous extract at different concentration (10%, 20%, 30%) was prepared by suckcele display. After the pilot study, 5 groups (50 rats) were dependent by subcotaneus injection with morphine. After insuring the animal dependency. First group has set as a testifire. Second group was affected with methadon treatment and other groups were treated by trachyspermum copticum at different concentration (10%, 20%, 30%). In all groups after naloxane injection by intraperitoneum injection, we studies morphine dependency that manifestated like diarrhea, weight loss and jumping. At 30% concentration, seven animals were deaed for the reason high concentration of extract. Data evaluation with ANOVA and LSD test showed that trachyspermum copticum is effective like methadone therapy to decrease withdrawal syndrome signs (p<0.05).

Background: Methanol is a toxic aliphatic alcohol that is widely used in industry as a solvent. Poisonings occur from accidental or awareness ingestion of it. Objective: In this study, the amount of methanol in ten plant water was evaluated. Methods: Five samples from each plant waters that related to six factories collected and analyzed by spectrophotometric method. Results: The results showed that the highest (1477.7  23.8 ppm) and the lowest (79.4  3 ppm) amount of methanol was related to dill and egiptial willow water, respectively. Conclusion: Since, the chronic use of plant water may induce methanol toxicity, it is recommended to determine a safe limit for it.

Background: Today, the tendency to use biodegradable biopolymers as one of the appropriate technologies to prevent food oxidation has received much attention. Objective: The aim of the present study was to produce a new biodegradable films containing free ethanolic extracts and nanocapsules of kak kosh biabani (Pulicaria gnaphalodes (Vent.) Boiss.), in order to investigate the antioxidant properties in laboratory conditions. Methods: In this study, the effects of different films on mechanical properties, antioxidant activities, encapsulation efficiency, water vapor permeability, microstructure and morphology and color characteristics were evaluated. Results: The average particle size was 153-166 nm and the encapsulation efficiency was 49.87-73.07%. Nanoliposomes with the lowest size and highest encapsulation efficiency were merged with the film samples. The results obtained from FT-IR spectra revealed new interactions between chitosan and nanoliposomes. Despite the increase in yellow color and decrease in whiteness indices, the nanoliposome composition improves the mechanical stiffness and results in reduced water vapor permeability (WVP). Conclusion: The properties of chitosan-zein films were affected by the amount of extract used, which generally improved the properties of the films and their antioxidant properties. Due to these features, this film can be used in food storage.