Volume 2, Issue 34 (6-2010)                   J. Med. Plants 2010, 2(34): 124-130 | Back to browse issues page

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Valadi A, Nasri S, Abbasi N, Amin G. Antinociceptive and Anti-inflammatory Effects of Hydroalchoholic Extract of Anethum graveolens L. seed . J. Med. Plants. 2010; 2 (34) :124-130
URL: http://jmp.ir/article-1-293-en.html
1- Department of Biology, Faculty of Science, PayamNoor University of Tehran
2- Department of Biology, Faculty of Science, PayamNoor University of Tehran , s_nasri2000@yahoo.com
3- Department of Pharmacology, Faculty of Medical, Ilam University of Medical Sciences
4- Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences
Abstract:   (3388 Views)
Background: There are many reports about anti-inflammatory effect of Anethum graveolens L.(A.g) in Iranian traditional medicine. In current decade, based on using of neutriceuticales for healing, the use of herbal drugs became very common. Objective: In this study, regarding the mentioned purposes, we have evaluated anti-inflammatory and antinociceptive effects of Hydroalchoholic Extract of A.g seeds. Methods: In this research, male mice were used and in inflammatory test they were divided to 6 groups: control, dexamethasone (15 mg/kg), seed A.g. extract (100,200, 400,500mg/kg). All of the drugs were administered intraperitonally. The inflammation was caused by xylene-induced ear oedema. In order to evaluate the antinocicetive of Anethum graveolens L. seed, we used formalin test. Mice were divided to 6 groups: control, seed A.g. extract (100,200, 400, 500 mg/kg). All of drugs were administered intraperitonally. Results: The results indicated that A.g. extract has anti-inflammatory and antinociceptive effects. Conclusion: This study suggests A.g extract as a candidate for pain relieving for further studies.
Full-Text [PDF 224 kb]   (1253 Downloads)    
Type of Study: Research |
Received: 2014/10/22 | Accepted: 2014/10/22 | Published: 2014/10/22

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