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:: دوره 3، شماره 35 - ( زبان: انگليسي- 1389 ) ::
جلد 3 شماره 35 صفحات 99-105 برگشت به فهرست نسخه ها
Antihistaminic and Anticholinergic Activity of Methanolic Extract of Barberry Fruit (Berberis vulgaris) in the Guinea- Pig Ileum
چکیده:   (1904 مشاهده)
Background: Barberry (Berberris vulgaris) is a well known medicinal plant in Iran and has also been used as food. Objective: This study was conducted to evaluate antihistaminic and anticholinergic activity of methanolic extract of barberry fruit. Methods: Methanolic extract was prepared and pharmacologically studied on isolated guinea- pig ileum, dose- response curves of histamine and acetylcholine with and without methanolic extract were plotted. Results: The pA2 values for antihistaminic activity of methanolic extract and dexchlorpheniramine were calculated (extract pA2± S.E.M = 3.53 ± 0.16 [-logC(g/l)] dexchlorpheniramine pA2 ± S.E.M.= 9.36 ± 0.14 ([-logC (M)]) and compared with each other. The pA2 values of anticholinergic activity of methanolic extract and atropine were also calculated (extract pA2± S.E.M = 4.18 ± 0.17 [-logC(g/)] atropine, PA2 +S.E.M = 8.99 ± 0.13 [-logC(M)]) and compared. Conclusion: The results indicated antihistaminic and anticholinergic activity of methanolic extract.
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نوع مطالعه: پژوهشي | موضوع مقاله: كنترل غذا و دارو
دریافت: ۱۳۹۳/۷/۲۸ | پذیرش: ۱۳۹۳/۷/۲۸ | انتشار: ۱۳۹۳/۷/۲۸
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Khosrokhavar R, Ahmadiani A, Shamsa F. Antihistaminic and Anticholinergic Activity of Methanolic Extract of Barberry Fruit (Berberis vulgaris) in the Guinea- Pig Ileum. JMP. 2010; 3 (35) :99-105
URL: http://jmp.ir/article-1-272-fa.html

Antihistaminic and Anticholinergic Activity of Methanolic Extract of Barberry Fruit (Berberis vulgaris) in the Guinea- Pig Ileum. فصلنامه گياهان دارويي. 1389; 3 (35) :99-105

URL: http://jmp.ir/article-1-272-fa.html



دوره 3، شماره 35 - ( زبان: انگليسي- 1389 ) برگشت به فهرست نسخه ها
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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