year 19, Issue 75 (9-2020)                   J. Med. Plants 2020, 19(75): 305-311 | Back to browse issues page

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Ebrahimi M, Daryabeigi R, Shahtalebi M A, Abedini F. Wound dressing of second degree burn by chamomile cream and Silver sulfadiazine cream; the effects on wound healing duration; a triple blind RCT. J. Med. Plants 2020; 19 (75) :305-311
1- Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
2- Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran ,
3- Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
4- Imam Musa Kazem Hospital, Isfahan, Iran
Abstract:   (5506 Views)
Background: Burn is the fourth most prevalent trauma around the world that many people are affected by it every year. One of the common methods of healing burn wounds is the use of Silver sulfadiazine cream 1%, the most important complication of which is the delay in healing of the wound. Objective: This study was done in order to identify and evaluate effective drugs in the treatment of burn wounds, in which the effect of chamomile cream and Silver sulfadiazine cream 1% on second-degree burn wound healing was compared. Methods: This triple-blind clinical trial was performed in Isfahan Burning Incidence Clinic. In this study, 67 patients with the inclusion criteria, with had second-degree burn wounds with an extended range of 1-10%, were randomly assigned to two groups, among whom, 34 patients with chamomile cream and 33 patients with Silver sulfadiazine cream were treated daily up to the time of healing the burn wounds. The duration of healing was evaluated according to a checklist. Data analysis was performed using SPSS software and the statistical tests of Chi-square, Mann-Whitney, independent t-test, and Fisher tests. Results: Data analysis showed that the mean healing time for wound healing in the treatment group with chamomile cream was 6.26 ± 0.96 day, and 10.42 ± 1.48 day in the Silver sulfadiazine group. Which, There was a significant difference between two groups (P < 0.001). Conclusion: Regarding the complication of Silver sulfadiazine cream 1% such as delayed wound healing and wound color change, Chamomile cream can be suggested as a natural alternative therapy in the treatment of superficial second-degree burns.
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Type of Study: Short Communication | Subject: Medicinal Plants
Received: 2018/11/30 | Accepted: 2019/04/28 | Published: 2020/09/6

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