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:: دوره 1، شماره 33 و S 6 - ( ويژه نامه شماره 6 (به زبان انگليسي) 1388 ) ::
جلد 1 شماره 33 و S 6 صفحات 29-34 برگشت به فهرست نسخه ها
Identification and Quantitative Determination of 4-Hydroxyisoleucine in Trigonella foenum-graecum L. from Iran
چکیده:   (1950 مشاهده)

  Background: The seeds of Trigonella foenum-graecum L. (Fenugreek) are used in Iranian traditional medicine as blood sugar lowering agent. According to last investigations, hypoglycemic property is related to the amino acids of the plant specially 4-hydroxyisoleucine.

  Objective: In this research, identification and quantitative determination of
4-hydroxyisoleucine in Fenugreek seeds from Shahreza, central part of Iran, has been investigated.

  Methods: Powdered seeds of the plant were defatted and then extracted by using ethanol 50%. In order to isolation of 4-hydroxyisoleucine from the extract, ion exchange chromatography was used and the amino acid content was determined by using high performance liquid chromatography technique.

  Results: The results showed the presence of 0.4% 4-hydroxyisoleucine in the plant seeds which is considerable amount of the amino acid in the plant collected from Iran.

Conclusion: According to the effects of 4-hydroxyisoleucine such as antihyperglycemic and antihyperlipidemic properties, fenugreek can be considered as an herbal remedy in supportive treatment of these disorders.
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نوع مطالعه: پژوهشي | موضوع مقاله: داروسازي عمومي
دریافت: ۱۳۹۳/۹/۱ | پذیرش: ۱۳۹۳/۹/۱ | انتشار: ۱۳۹۳/۹/۱
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Hajimehdipoor H, Sadat-Ebrahimi S, Amanzadeh Y, Izaddoost M, Givi E. Identification and Quantitative Determination of 4-Hydroxyisoleucine in Trigonella foenum-graecum L. from Iran. JMP. 2010; 1 (33) :29-34
URL: http://jmp.ir/article-1-505-fa.html

Identification and Quantitative Determination of 4-Hydroxyisoleucine in Trigonella foenum-graecum L. from Iran. فصلنامه گياهان دارويي. 1388; 1 (33) :29-34

URL: http://jmp.ir/article-1-505-fa.html



دوره 1، شماره 33 و S 6 - ( ويژه نامه شماره 6 (به زبان انگليسي) 1388 ) برگشت به فهرست نسخه ها
فصلنامه علمی پژوهشی گیاهان دارویی Journal of Medicinal Plants
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