Volume 2, Issue 70 (5-2019)                   J. Med. Plants 2019, 2(70): 144-153 | Back to browse issues page

DOI: 10.29252/jmp.2.70.144


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Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran , fateme.halalkhor@gmail.com
Abstract:   (708 Views)
Background: Obesity is associated with increased oxidative stress. In addition, exercise can increase oxidative stress effects. However, the use of dietary supplements may moderate these indices.
Objective: The present study is conducted to assess the effect of flaxseed supplementation on the total antioxidant capacity and lipid peroxidation after four weeks concurrent training in overweight women.
Methods: Thirty six overweight women with BMI> 25 were randomly divided into four groups of 9 people, including supplementary training, concurrent training, supplementation flaxseed and control. All written consent was taken. Concurrent training included aerobic exercises with an intensity of 65% of heart rate and resistance training with intensity of 60% 1RM In between the Flaxseed powder (0.62 g per kg of body weight per day) was supplemented during the four-week period. Hypothesis research at the level of significance P <0.05 was used to analyze the variance (ANOVA) with repeated measurements with inter-group factor.
Results: The results showed that the concentration of malondialdehyde biomarker in the non-flax seed group increased significantly after the concurrent training (P <0.05). However, the total antioxidant capacity of plasma was not significantly different (P> 0.05).
Conclusion: The results of this study indicated that acute concurrent Physical activity give rise to increased MDA concentration in overweight women. The application of flaxseed extract employed as an antioxidant supplement might ameliorate this marker and prevent the oxidative stress damage.
Full-Text [PDF 372 kb]   (245 Downloads)    
Type of Study: Research |
Received: 2018/04/9 | Accepted: 2018/06/25 | Published: 2019/05/26

References
1. Kazemi M, Marandi S M, Movahedian Attar A, Haghighatian M and Rezaei Z. Effect of acute exercise on total antioxidant capacity and hydrogen peroxide in male Wistar rats: J. Practical Studies At Biosciences In Sport 2014; 2 (3): 29- 37.
2. Ga'ini A A, Sheikholeslami Vatan D, Ashrafi Helen J and Mogharnasi M. Short-term and long-term effects of three types of fasting, endurance and combination of sport activity on the amount of lactate hydrogenase, creatine kinase and plasma malondialdehyde in rats. Sports Journal of Sport Sciences 2011; 3 (8): 5-20.
3. Forsythe L K, Wallace J M and Livingstone M B E. Obesity and inflammation: the effects of weight loss. Nutrition Research Rev. 2008; 21 (2): 117-133. [DOI:10.1017/S0954422408138732]
4. Parisi S M and Goodman E. Obesity and cardiovascular disease risk in children and adolescents. Current Cardiovascular Risk Reports 2008; 2 (1): 47-52. [DOI:10.1007/s12170-008-0010-7]
5. Atashak S, Niloufari A and Azizbighi K. The effect of short-term supplemental Blackberry extract on total antioxidant capacity of the plasma and lipid oxidation index of obese men following one session of resistance activity. Food Science and Nutrition 2014; 11 (spring 1393): 55-62.
6. Thirumalai T, Therasa S V, Elumalai E and David E. Intense and exhaustive exercise induce oxidative stress in skeletal muscle. Asian Pacific J. Tropical Disease 2011; 1 (1): 63-66. [DOI:10.1016/S2222-1808(11)60016-9]
7. Jahani G, Firoozrai M, Matin Homaee H, Tarverdizadeh B, Azarbayjani M A, Movaseghi G R, Sarasghani M R and Hedayatzadeh R. The Effect of Continuous and Regular Exercise on Erytrocyte Antioxidative Enzymes Activity and Stress Oxidative in Young Soccer Players. Razi J. Medical Sciences 2010; 17 (74): 22-32.
8. Azamian Jazi A and Shokouhi R. The Effect of an Eight Week Combined Exercise Training on Oxidative Stress and Lipid Peroxidation in Postmenopausal Women with Type 2 Diabetes. The Journal of Shahid Sadoughi University of Medical Sciences 2016; 24 (8): 667-678.
9. Vincent H K, Morgan J W and Vincent K R. Obesity exacerbates oxidative stress levels after acute exercise. Medicine and Science in Sports and Exercise 2004; 36 (5): 772-779. [DOI:10.1249/01.MSS.0000126576.53038.E9]
10. Shahla S P, Adela J, Mohammad K, Abdolfattah S, Tahereh C o S and hamidreza S. The effect of oxidative stress in immature rat rats with varicocele. Physiology and Pharmacol. 1390; 3 (15):416-426.
11. Adolphe J L, Whiting S J, Juurlink B H, Thorpe L U and Alcorn J. Health effects with consumption of the flax lignan secoisolariciresinol diglucoside. British Journal of Nutrition 2010; 103 (7): 929-938. [DOI:10.1017/S0007114509992753]
12. Yang W, Fu J, Yu M, Huang Q, Wang D, Xu J, Deng Q, Yao P, Huang F and Liu L. Effects of flaxseed oil on anti-oxidative system and membrane deformation of human peripheral blood erythrocytes in high glucose level. Lipids in Health and Disease 2012; 11 (1): 88. [DOI:10.1186/1476-511X-11-88]
13. Xu J, Gao H, Song L, Yang W, Chen C, Deng Q, Huang Q and Huang F. Flaxseed oil and alpha-lipoic acid combination ameliorates hepatic oxidative stress and lipid accumulation in comparison to lard. Lipids in Health and Disease 2013; 12 (1): 58. [DOI:10.1186/1476-511X-12-58]
14. DiCarlo L, Sparling P, Millard-Stafford M and Rupp J. Peak heart rates during maximal running and swimming: implications for exercise prescription. International J. Sports Med. 1991; 12 (03): 309-312. [DOI:10.1055/s-2007-1024687]
15. Soori R, Rezaeian N, Khosravi N, Ahmadizad S, Taleghani H, Jourkesh M and Stannard S. Effects of water-based endurance training, resistance training, and combined water and resistance training programs on visfatin and ICAM-1 levels in sedentary obese women. Science & Sports 2017; 32 (3): 144-151. [DOI:10.1016/j.scispo.2016.12.004]
16. Agha Alinejad H, Mehrabani J, Ansari Dogahe R and Piri M. The Influence of Resistance, Endurance, and Combined Resistance-endurance Exercise Training on Interleukin-18 and C-reactive Protein Level in Inactive Female Adolescents. Tabari Journal of Preventive Medicine 2016; 2 (1): 38-47.
17. Ursoniu S, Sahebkar A, Andrica F, Serban C and Banach M. Effects of flaxseed supplements on blood pressure: A systematic review and meta-analysis of controlled clinical trial. Clinical Nutrition 2016; 35 (3): 615-625. [DOI:10.1016/j.clnu.2015.05.012]
18. Ju Y. Can flaxseed lower cholesterol levels? Produced by Virginia Cooperative Extension. 2017, pp: 1-7.
19. Radovanovic D, Bratic M, Nurkic M, Cvetkovic T, Ignjatovic A and Aleksandrovic M. Oxidative stress biomarker response to concurrent strength and endurance training. Gen. Physiol. Biophys. 2009; 28 (Special Issue): 205-211.
20. Azizbeigi K, Stannard S R, Atashak S and Haghighi MM. Antioxidant enzymes and oxidative stress adaptation to exercise training: comparison of endurance, resistance, and concurrent training in untrained males. Journal of Exercise Science & Fitness 2014; 12 (1): 1-6. [DOI:10.1016/j.jesf.2013.12.001]
21. Schaun M I, Dipp T, Silva Rossato J, Wilhelm E N, Pinto R, Rech A, Plentz R D M, Homem de Bittencourt P I and Reischak‐Oliveira A. The effects of periodized concurrent and aerobic training on oxidative stress parameters, endothelial function and immune response in sedentary male individuals of middle age. Cell Biochemistry and Function 2011; 29 (7): 534-542. [DOI:10.1002/cbf.1781]
22. Vezzoli A, Pugliese L, Marzorati M, Serpiello F R, La Torre A and Porcelli S. Time-course changes of oxidative stress response to high-intensity discontinuous training versus moderate-intensity continuous training in masters runners. PLoS One 2014; 9 (1): e87506. [DOI:10.1371/journal.pone.0087506]
23. Abbasali G, Dariush S V, Jawad A H and Mahdi M. Short-term and long-term effects of three types of exercise activity, endurance and combination on the amount of lactate hydrogenase, creatine kinase and malondialdehyde in rats. Sports Sciences (Motion) 1390; 8: 5-20.
24. Jangale N M, Devarshi P P, Dubal A A, Ghule A E, Koppikar S J, Bodhankar S L, Chougale A D, Kulkarni M J and Harsulkar A M. Dietary flaxseed oil and fish oil modulates expression of antioxidant and inflammatory genes with alleviation of protein glycation status and inflammation in liver of streptozotocin-nicotinamide induced diabetic rats. Food Chem. 2013; 141 (1): 187-195. [DOI:10.1016/j.foodchem.2013.03.001]
25. Asif M. Health effects of omega-3, 6, 9 fatty acids: Perilla frutescens is a good example of plant oils. Oriental Pharmacy & Experimental Medicine 2011; 11 (1): 51-59. [DOI:10.1007/s13596-011-0002-x]
26. Pilar B C, da Costa Güllich A A, Ströher D J, Zuravski L, Mezzomo J, Coelho R P, Faoro D, Piccoli J d C E and Manfredini V. 28-days dietary supplementation with golden flaxseed improves biochemical and oxidative parameters in patients with metabolic syndrome. Journal of Functional Foods 2014; 10: 232-242. [DOI:10.1016/j.jff.2014.06.020]
27. Katare C, Saxena S, Agrawal S, Prasad G and Bisen P. Flax seed: a potential medicinal food. J. Nutr. Food Sci. 2012; 2 (120): 2. [DOI:10.4172/2155-9600.1000120]
28. Waszkowiak K and Barthet V J. Characterization of a Partially Purified Extract from Flax (Linum usitatissimum L.) Seed. Journal of the American Oil Chemists' Society 2015; 92 (8): 1183.1194. [DOI:10.1007/s11746-015-2676-6]
29. Poorhassan M, Mahakizadeh S, Bazrafkan M, Nikmehr B, Abolhassani F, Ijaz S, Yamini N, Dashti N, Akbari M and Hassanzadeh G. Flaxseed can reduce the damages induced by hypoxia in the testis of rat. Int. J. Fertil. Steril. 2017; 12 (3): 7-1.
30. Mokhtari T, Faghir Ghanesefat H, Hassanzadeh G, Moayeri A, Jafar Haeri S M, Rezaee Kanavee A and Mousavi S M. Effects of Flaxseed oil supplementation on renal dysfunction due to ischemia/reperfusion in rat. Journal of Basic Research in Medical Sciences 2017; 4 (1): 22-29. [DOI:10.18869/acadpub.jbrms.4.1.22]