سال 18، شماره 72 - ( 8-1398 )                   سال 18 شماره 72 صفحات 1-22 | برگشت به فهرست نسخه ها


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Naseri L, Akbari bazm M, Khazaei M. A Review on Therapeutic Effects of Tribulus terrestris. J. Med. Plants. 2019; 18 (72) :1-22
URL: http://jmp.ir/article-1-2700-fa.html
ناصری لیلا، اکبری بزم محسن، خزاعی مظفر. مروری بر اثرات درمانی گیاه خارخاسک. فصلنامه گياهان دارویی. 1398; 18 (72) :1-22

URL: http://jmp.ir/article-1-2700-fa.html


1- دانشجوی دکتری علوم تشریح، مرکز تحقیقات باروری و ناباروری، پژوهشکده فناوری سلامت، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران
2- استاد، مرکز تحقیقات باروری و ناباروری، پژوهشکده فناوری سلامت، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران ، Mkhazaei1345@yahoo.com
چکیده:   (2869 مشاهده)
خارخاسک (Tribulus terrestris)، گیاهی یکساله بوده که در مناطق گرم و مرطوب، در نواحی مدیترانه و نواحی گرم اروپا، آسیا، آفریقا و استرالیا پراکنده است. این گیاه دارای فواید مختلفی بوده و در طب سنتی برای درمان انواع بیماری‌ها از جمله دفع سنگ کلیه، کاهش فشار خون، خواص ضد دیابتی، درمان بیماری‌های دستگاه قلبی-عروقی، اختلالات معدی-روده‌ای، تقویت عملکرد جنسی در مردان و درمان بیماری‌های کبدی توصیه می‌شود. هدف این مطالعه بررسی خواص درمانی و فارماکولوژیک خارخاسک در منابع طب سنتی و مقالات علمی در طب مدرن است. این مطالعه یک مرور سیستماتیک است که بر اساس چک لیستPRISMA  انجام گرفت. بر اساس کلید واژه‌ها، 440 عنوان انتخاب و پس از حذف مقالات تکراری، 129 مقاله از پایگاه‌های مختلف از جمله PubMed،SID،ScienceDirect ، Scopus ، Magiran و موتور جستجوی Google Scholar بدون محدودیت زمانی استخراج شد. خارخاسک دارای خواص متعددی از جمله خاصیت ضد میکروبی و ضد باکتریایی، پاکسازی رادیکال‌های آزاد و مهار پراکسیداسیون چربی است و از طریق مکانیسم‌های مختلف سلولی و مولکولی موجب خواص مختلف فارماکولوژیک و درمانی می‌شود. از جمله مهم‌ترین خواص درمانی این گیاه خواص ضد التهابی و ضد سرطانی است. همچنین مطالعات متعدد بالینی نشان دادند که مصرف توأم عصاره خارخاسک با داروهای شیمی درمانی موجب کاهش عوارض جانبی داروها می‌شود. با توجه فقدان سمیت و خواص متنوع خارخاسک، مصرف ترکیبات این گیاه به عنوان مکمل دارویی در رژیم های درمانی جهت بیماری‌های مختلف مورد توجه قرار گرفته است.
واژه‌های کلیدی: خارخاسک، طب سنتی، گیاه دارویی
متن کامل [PDF 500 kb]   (1370 دریافت)    
نوع مطالعه: مروری | موضوع مقاله: فارماكولوژی و سم شناسی
دریافت: 1397/4/8 | پذیرش: 1397/7/3 | انتشار: 1398/8/6
* نشانی نویسنده مسئول: استاد، مرکز تحقیقات باروری و ناباروری، پژوهشکده فناوری سلامت، دانشگاه علوم پزشکی کرمانشاه، کرمانشاه، ایران

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