سال 11، شماره 43 - ( English 1391 )
سال 11 شماره 43 صفحات 89-80 |
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Hosseini N, Akbari M, Ghafarzadegan R, Changizi Ashtiyani S, Shahmohammadi R. Total Phenol, Antioxidant and Antibacterial Activity of the Essential Oil and Extracts of Ferulago angulata ssp. angulata. , J. Med. Plants. 2012; 11 (43) :80-89
URL: http://jmp.ir/article-1-145-fa.html
URL: http://jmp.ir/article-1-145-fa.html
Hosseini N، Akbari M، Ghafarzadegan R، Changizi Ashtiyani S، Shahmohammadi R. Total Phenol, Antioxidant and Antibacterial Activity of the Essential Oil and Extracts of Ferulago angulata ssp. angulata. , فصلنامه گياهان دارویی. 1391; 11 (43) :80-89
N Hosseini*1 
، M Akbari2 ، R Ghafarzadegan3 
، S Changizi Ashtiyani4 ، R Shahmohammadi5
، M Akbari2 ، R Ghafarzadegan3 ، S Changizi Ashtiyani4 ، R Shahmohammadi5
1- Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak, Iran ، na_hosseini@ymail.com
2- Department of Microbiology, Arak University of Medical Sciences, Arak, Iran
3- Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran
4- Department of Physiology, Arak University of Medical Sciences, Arak, Iran
5- Department of Biology, University of Guilan, Rasht, Iran
2- Department of Microbiology, Arak University of Medical Sciences, Arak, Iran
3- Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran
4- Department of Physiology, Arak University of Medical Sciences, Arak, Iran
5- Department of Biology, University of Guilan, Rasht, Iran
چکیده: (7723 مشاهده)
Background: In recent years, plants natural products have gained considerable attention as natural preservers for use in different industries. Due to their free radical scavenging activities, phenolic compounds can prevent a wide range of diseases such as cancers and cardiovascular and neurodegenerative diseases. For a long time, different Ferulago species have been in use as medicinal plants worldwide.
Objective: The aim of this research was to investigate total phenolics and the antioxidant and antibacterial activities of essential oil and different extracts from F. angulata growing wild in Iran.
Methods: Antioxidant activity of our samples was examined by DPPH assay and their phenolic content was determined using the Folin – Ciocalteau method. Moreover, their inhibitory effects against five gram-negative and gram-positive bacteria including Shigella boidii, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis were tested by using the disk diffusion method.
Results: Ethyl acetate fraction and methanol extract contained the highest levels of phenolic compounds (229.2 and 202.9 µg/mg galic acid) in this study. Also, essential oil of this plant exhibited low free radical scavenging activity (IC50= 36129.43µg/ml). On the other hand, ethyl acetate and aqueous fractions had the highest antioxidant activity (IC50 values of 20.153 and 28.28 µg/ml, respectively). Finally, studied samples had no significant antibacterial activities against tested organisms.
Conclusion: The essential oil of this plant can be used as a flavoring agent while extracts prepared from it have the potential to be used as natural antioxidants in relevant industries.
Objective: The aim of this research was to investigate total phenolics and the antioxidant and antibacterial activities of essential oil and different extracts from F. angulata growing wild in Iran.
Methods: Antioxidant activity of our samples was examined by DPPH assay and their phenolic content was determined using the Folin – Ciocalteau method. Moreover, their inhibitory effects against five gram-negative and gram-positive bacteria including Shigella boidii, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Enterococcus faecalis were tested by using the disk diffusion method.
Results: Ethyl acetate fraction and methanol extract contained the highest levels of phenolic compounds (229.2 and 202.9 µg/mg galic acid) in this study. Also, essential oil of this plant exhibited low free radical scavenging activity (IC50= 36129.43µg/ml). On the other hand, ethyl acetate and aqueous fractions had the highest antioxidant activity (IC50 values of 20.153 and 28.28 µg/ml, respectively). Finally, studied samples had no significant antibacterial activities against tested organisms.
Conclusion: The essential oil of this plant can be used as a flavoring agent while extracts prepared from it have the potential to be used as natural antioxidants in relevant industries.
واژه‌های کلیدی: Ferulago angulata ssp. angulata، Antioxidant activity، Antibacterial activity، Total phenolics
نوع مطالعه: پژوهشی |
موضوع مقاله:
فارماكوگنوزی و فارماسيوتيكس
دریافت: 1391/6/25 | پذیرش: 1391/8/3 | انتشار: 1391/9/30
دریافت: 1391/6/25 | پذیرش: 1391/8/3 | انتشار: 1391/9/30
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