en Phytochemical and Biological Studies on the Different Organs of <i>Tanacetum parthenium</i> L. Cultivated in Egypt فارماكوگنوزی و فارماسيوتيكس Pharmacognosy & Pharmaceutics مروری Review <div dir="ltr" style="text-align: justify;"><span new="" roman="" times="">Phytochemical investigation of <i>Tanacetum parthenium </i>L. family Asteraceae cultivated in <place w:st="on"><country-region w:st="on">Egypt</country-region></place> resulted in isolation and identification of four flavonoids. One surface flavonoid was isolated from the fresh leaves and three other flavonoids were isolated from the flower heads. Four sesquiterpene lactones were isolated from the leaves. Two sterols were isolated from the roots. A comparative study of the essential oil content of the leaves and the flower heads was performed using GC/MS. The results revealed the presence of 42 and 30 components in the leaves and the flower heads oil samples, respectively. The major components of both oil samples were camphor (constituted 37.7% and 48.4%) and chrysanthenyl acetate (constituted 33.8% and 26.3%) in the leaves and the flower heads, respectively. Different extracts of <i>T. parthenium</i> L. showed significant biological activities. Analgesic, anti-inflammatory, antipyretic, antispasmodic and uterine-stimulant activities were studied in addition to the <i>in vitro</i> cytotoxic effect.</span></div> <div style="text-align: justify;"><span new="" roman="" style="FONT-FAMILY: " times="">Phytochemical investigation of <i>Tanacetum parthenium </i>L. family Asteraceae cultivated in <place w:st="on"><country-region w:st="on">Egypt</country-region></place> resulted in isolation and identification of four flavonoids. One surface flavonoid was isolated from the fresh leaves and three other flavonoids were isolated from the flower heads. Four sesquiterpene lactones were isolated from the leaves. Two sterols were isolated from the roots. A comparative study of the essential oil content of the leaves and the flower heads was performed using GC/MS. The results revealed the presence of 42 and 30 components in the leaves and the flower heads oil samples, respectively. The major components of both oil samples were camphor (constituted 37.7% and 48.4%) and chrysanthenyl acetate (constituted 33.8% and 26.3%) in the leaves and the flower heads, respectively. Different extracts of <i>T. parthenium</i> L. showed significant biological activities. Analgesic, anti-inflammatory, antipyretic, antispasmodic and uterine-stimulant activities were studied in addition to the <i>in vitro</i> cytotoxic effect.</span></div> Tanacetum parthenium, Santin, Parthenolide, Camphor, Chrysanthenyl acetate, Analgesic, Anti - inflammatory, Antipyretic, Antispasmodic, Uterine stimulant and cytotoxic Tanacetum parthenium, Santin, Parthenolide, Camphor, Chrysanthenyl acetate, Analgesic, Anti - inflammatory, Antipyretic, Antispasmodic, Uterine stimulant and cytotoxic 8 22 http://jmp.ir/browse.php?a_code=A-10-419-1&slc_lang=en&sid=1 MEM Rateb MEM Rateb mostafa19772002@yahoo.com 100319475328460038816 100319475328460038816 Yes Pharmacognosy Department, Faculty of Pharmacy, Beni-Sueif University, Egypt Pharmacognosy Department, Faculty of Pharmacy, Beni-Sueif University, Egypt AAM El-Gendy AAM El-Gendy 100319475328460038817 100319475328460038817 No Pharmacology Department, Faculty of Veterinary Medicine, Beni - Sueif University, Egypt Pharmacology Department, Faculty of Veterinary Medicine, Beni - Sueif University, Egypt SS El-Hawary SS El-Hawary 100319475328460038818 100319475328460038818 No Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt AM El - Shamy AM El - Shamy 100319475328460038819 100319475328460038819 No Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Egypt