en Antidepressant Effect of <i>Crocus sativus</i>: an Evidence Based Review فارماكوگنوزی و فارماسيوتيكس Pharmacognosy & Pharmaceutics مروری Review <div dir="ltr" style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Tahoma;"><span new="" roman="" times="">Depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral and physiological levels. Full remission is achieved in fewer than 50% of patients. Therefore, antidepressant or medications that achieve a better rate of success are urgently needed. Herbal medicine has a long and respected history, and holds a valuable place in the treatment of depression. <span class="fullpost">According to medical studies, saffron can be used to treat depression. This paper reviews the clinical studied regarding the antidepressant effect of saffron</span></span></span></span></div> <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Tahoma;"><span new="" roman="" times="">Depression is a heterogeneous disorder often manifested with symptoms at the psychological, behavioral and physiological levels. Full remission is achieved in fewer than 50% of patients. Therefore, antidepressant or medications that achieve a better rate of success are urgently needed. Herbal medicine has a long and respected history, and holds a valuable place in the treatment of depression. <span class="fullpost">According to medical studies, saffron can be used to treat depression. This paper reviews the clinical studied regarding the antidepressant effect of saffron</span></span></span></span></div> <,i>,Crocus sativus<,/i>,, Saffron, Antidepressant <,i>,Crocus sativus<,/i>,, Saffron, Antidepressant 35 38 http://jmp.ir/browse.php?a_code=A-10-34-12&slc_lang=en&sid=1 M Kamalipour کمالی پور 100319475328460038093 100319475328460038093 No Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran A.H Jamshidi امیرحسین جمشیدی 100319475328460038094 100319475328460038094 No Department of Pharmacognosy & Pharmaceutics, Institute of Medicinal Plants, ACECR, Karaj Department of Pharmacognosy & Pharmaceutics, Institute of Medicinal Plants, ACECR, Karaj S Akhondzadeh شاهین آخوندزاده s.akhond@neda.net 100319475328460038095 100319475328460038095 Yes Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran