en تأثیر تمرینات عملکردی با شدت بالا همراه با مکمل تیلاکوئید بر اینترلوکین 1 بتا و اینترلوکین 8 در مردان چاق گياهان دارویی Medicinal Plants پژوهشی Research <div style="text-align: justify;"><b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Background</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">: </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Obesity is a widespread public health concern with a growing global prevalence, leading to an increased risk of chronic metabolic conditions. Despite this, research on the impact of exercise and supplementation on inflammatory factors in obese individuals is limited.</span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> <b>Objective</b>: </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">This study evaluates the effects of high-intensity functional training (HIFT) and Thylakoid supplementation on interleukins-1beta and interleukin-8 levels in obese individuals.</span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> <b>Methods:</b> </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">In this study, 44 obese men were allocated into four groups: control (C), Thylakoid supplement (T), HIFT (H), and a combination of supplements and exercise (HT). Participants followed the HIFT exercise protocol for 12 weeks, while those in the supplement groups received Thylakoid supplement for the same duration. Body mass index, inflammatory biomarkers were assessed through blood samples before and after the 12-week intervention.</span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""> <b>Results</b>: </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">In these groups, H, T, and HT, the levels of inflammatory factors interleukin-1beta and interleukin-8 were compared. In the case of interleukin-8 a significant difference was observed in the H and HT groups compared to the T group. Also, significant decrease in interleukin-1beta level was observed in all groups, H, T, and HT, compared to the control group (P < 0.001). Interestingly, the mentioned factors in both H and HT groups also showed a significant difference (P < 0.001).</span></span> <b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Conclusion</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">: </span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">The findings of the study showed that the HIFT protocol and the use of thylakoid supplements can reduce systemic inflammatory indicators in obese men by showing a synergy effect. Therefore, HIFT exercise with thylakoid supplements can be considered an effective way to reduce inflammation in obese people.</span></span></div> Obesity, High intensity functional training, Thylakoid, IL-1beta, IL-8 69 81 http://jmp.ir/browse.php?a_code=A-10-7004-1&slc_lang=en&sid=1 Heidar EbadiAsl حیدر عبادی‌اصل h.ebadi@ut.ac.ir 100319475328460047819 0009-0007-5269-7937 No Department of Exercise Physiology, University of Guilan, Guilan, Iran گروه فیزیولوژی ورزشی، دانشگاه گیلان، گیلان، ایران Bahman Mirzaei بهمن میرزایی mirzaei@united-world-wrestling.org 100319475328460047820 100319475328460047820 No Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, Iran گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه گیلان، گیلان، ایران Arsalan Damirchi ارسلان دمیرچی damirchi@guilan.ac.ir 100319475328460047821 100319475328460047821 Yes Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Guilan, Iran گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه گیلان، گیلان، ایران