en Nano-Elicitation of Secondary Pharmaceutical Metabolites in Plant Cells: A Review كشاورزی و اتنوبوتانی Agriculture & Ethnobotany پژوهشی Research <div dir="ltr" style="text-align: justify;">In recent years, metabolism researches using nanomaterials have been focusing on human and animal cells, and therefore very limited data are available about influence of nanomaterials on biosynthesis of secondary metabolites in plant cells. Plants produce different types of secondary metabolites including terpenoids, phenolics, tannins, and alkaloids, which are known to act as vital mediators for the interaction with other living (biotic) or non-living (abiotic) agents under stressful conditions. Elicitors may induce physiological and biochemical processes of the target plants and activate defense mechanisms. Application of signaling molecules as elicitors has evolved an efficient technique for the production of pharmaceutically active compounds in plants. However, relatively little has been done regarding the application of nanomaterials as potential elicitors for production of industrially valuable compounds. Here, we provide studies proving that nanomaterials can function as elicitors of plant defensive chemistry that are mostly accompanied by enhanced production of different secondary metabolites.</div> <div style="text-align: justify;">In recent years, metabolism researches using nanomaterials have been focusing on human and animal cells, and therefore very limited data are available about influence of nanomaterials on biosynthesis of secondary metabolites in plant cells. Plants produce different types of secondary metabolites including terpenoids, phenolics, tannins, and alkaloids, which are known to act as vital mediators for the interaction with other living (biotic) or non-living (abiotic) agents under stressful conditions. Elicitors may induce physiological and biochemical processes of the target plants and activate defense mechanisms. Application of signaling molecules as elicitors has evolved an efficient technique for the production of pharmaceutically active compounds in plants. However, relatively little has been done regarding the application of nanomaterials as potential elicitors for production of industrially valuable compounds. Here, we provide studies proving that nanomaterials can function as elicitors of plant defensive chemistry that are mostly accompanied by enhanced production of different secondary metabolites.</div> Elicitation, Nanoelicitor, Nanoparticles, Plant secondary metabolites, Reactive oxygen species Elicitation, Nanoelicitor, Nanoparticles, Plant secondary metabolites, Reactive oxygen species 6 36 http://jmp.ir/browse.php?a_code=A-10-69-23&slc_lang=en&sid=1 M Hatami M Hatami m-hatami@araku.ac.ir 100319475328460035032 100319475328460035032 Yes Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, 38156-8-8349, Arak, Iran Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, 38156-8-8349, Arak, Iran H Naghdi Badi H Naghdi Badi 100319475328460035033 100319475328460035033 No Medicinal Plants Research Centre, Institute of Medicinal Plants, ACECR, Karaj, Iran Medicinal Plants Research Centre, Institute of Medicinal Plants, ACECR, Karaj, Iran M Ghorbanpour M Ghorbanpour 100319475328460035034 100319475328460035034 No Institute of Nanoscience and Nanotechnology, Arak University, Arak, Iran Institute of Nanoscience and Nanotechnology, Arak University, Arak, Iran