fa Antioxidant Activity of some Medicinal Species using FRAP Assay فارماكوگنوزی و فارماسيوتيكس Pharmacognosy & Pharmaceutics مروری Review <div style="text-align: justify;"><strong>Background:</strong> Medicinal plants (especially belong to Lamiaceae family) are potential sources of new drugs to improve the treatment of diseases whose treatment is associated to anti-oxidative agents. In this paper, the Ferric Reducing Ability of Plasma (FRAP) activity of some Lamiaceae and Apiaceae species, has been evaluated. <strong>Methods:</strong> Aerial parts of the plants were dried, cut into small pieces and extracted with ethyl acetate and methanol, respectively, by percolation at room temperature. Different concentrations of the plant extracts were investigated for antioxidant power using FRAP assay. <strong>Results:</strong> The extracts showed a considerable antioxidant effect from 16.36 mmol of FeSO4/100 g dry plant equivalents in <em>Scutellaria tornefortii</em> (AcOEt extract) to 404.12 mmol of FeSO4/100 g dried plant in <em>Salvia macrosiphon </em>(MeOH extract). <strong>Conclusions:</strong> All the plant samples possessed antioxidant activity, while Salvia macrosiphon (MeOH extract),<em> Pimpinella tragioides</em> (MeOH extract) and <em>Salvia limbata</em> (AcOEt extract) showed significantly the highest results and <em>Scutellaria tornefortii</em> (AcOEt extract) showed the lowest power. Antioxidant activity of these species might be due to the presence of flavonoids, rosmarinic acid, coumarins even monoterpenes (like myrcene) in the plant extracts.</div> <div style="text-align: justify;"><strong>Background:</strong> Medicinal plants (especially belong to Lamiaceae family) are potential sources of new drugs to improve the treatment of diseases whose treatment is associated to anti-oxidative agents. In this paper, the Ferric Reducing Ability of Plasma (FRAP) activity of some Lamiaceae and Apiaceae species, has been evaluated. <strong>Methods:</strong> Aerial parts of the plants were dried, cut into small pieces and extracted with ethyl acetate and methanol, respectively, by percolation at room temperature. Different concentrations of the plant extracts were investigated for antioxidant power using FRAP assay. <strong>Results:</strong> The extracts showed a considerable antioxidant effect from 16.36 mmol of FeSO4/100 g dry plant equivalents in <em>Scutellaria tornefortii</em> (AcOEt extract) to 404.12 mmol of FeSO4/100 g dried plant in <em>Salvia macrosiphon </em>(MeOH extract). <strong>Conclusions:</strong> All the plant samples possessed antioxidant activity, while Salvia macrosiphon (MeOH extract),<em> Pimpinella tragioides</em> (MeOH extract) and <em>Salvia limbata</em> (AcOEt extract) showed significantly the highest results and <em>Scutellaria tornefortii</em> (AcOEt extract) showed the lowest power. Antioxidant activity of these species might be due to the presence of flavonoids, rosmarinic acid, coumarins even monoterpenes (like myrcene) in the plant extracts.</div> Antioxidant power, FRAP, Lamiaceae, Apiaceae, <,i>,Salvia macrosiphon<,/i>,, <,i>,Pimpinella tragioides<,/i>, Antioxidant power, FRAP, Lamiaceae, Apiaceae, <,i>,Salvia macrosiphon<,/i>,, <,i>,Pimpinella tragioides<,/i>, 54 60 http://jmp.ir/browse.php?a_code=A-10-161-2&slc_lang=fa&sid=1 AR Gohari AR Gohari 100319475328460037625 100319475328460037625 No Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran H Hajimehdipoor H Hajimehdipoor 100319475328460037626 100319475328460037626 No S Saeidnia S Saeidnia saeidnia_s@tums.ac.ir 100319475328460037627 100319475328460037627 Yes Medicinal Plants Research Center, Tehran University of Medical Sciences Traditional Medicine and Materia Medica Research Center and School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Y Ajani Y Ajani 100319475328460037628 100319475328460037628 No Department of Pharmacognosy, Institute of Medicinal Plants, ACECR, Tehran, Iran Department of Pharmacognosy, Institute of Medicinal Plants, ACECR, Tehran, Iran A Hadjiakhoondi A Hadjiakhoondi 100319475328460037629 100319475328460037629 No Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran Medicinal Plants Research Center, Tehran University of Medical Sciences, Tehran, Iran