fa Sterols and Flavonoids of <i>Lomatopodium staurophyllum</i> فارماكوگنوزی و فارماسيوتيكس Pharmacognosy & Pharmaceutics پژوهشی Research <div dir="ltr" style="text-align: justify;"><strong>Background:</strong> The genus <em>Lomatopodium</em> Fisch. & C.A.Mey., belongs to Apiaceae family and contains one herbaceous species growing wildly in Iran. There are only a few papers about the chemical constituents of these plants. Here, we focused on the isolation and identification of the main flavonoid glycosides and sterols from the aerial parts of <em>L. staurophyllum</em>, which has not been previously reported. <strong>Methods:</strong> Flowered aerial parts of the plant were dried and cut into small pieces, then extracted with ethyl acetate and methanol by percolation at room temperature. The separation process was carried out using several chromatographic methods. Structural elucidation was based on NMR and MS data, in comparison with those reported in the literature. <strong>Results: </strong>The isolated compounds from ethyl acetate and methanol extracts of <em>L. staurophyllum </em>were identified as nonanal (1), stigmasterol acetate (2), beta-sitosterol (3), quercetin 3-O-glucoside (4) and quercetin 3 &ndash; O - rhamnoglucoside (5) by comparison of their NMR spectral data with those reported in the literature. <strong>Conclusion:</strong> Ethyl acetate and methanol extracts of <em>L. staurophyllum</em> contain various flavonol glycosides and sterols as the main components. Pelargonic aldehyde (nonanal), a growth promoting factor in plant cells, is found to be occurred in this species and might be a cause of anti -diarrhea activity.</div> <div dir="ltr" style="text-align: justify;"><strong>Background:</strong> The genus <em>Lomatopodium</em> Fisch. & C.A.Mey., belongs to Apiaceae family and contains one herbaceous species growing wildly in Iran. There are only a few papers about the chemical constituents of these plants. Here, we focused on the isolation and identification of the main flavonoid glycosides and sterols from the aerial parts of <em>L. staurophyllum</em>, which has not been previously reported. <strong>Methods:</strong> Flowered aerial parts of the plant were dried and cut into small pieces, then extracted with ethyl acetate and methanol by percolation at room temperature. The separation process was carried out using several chromatographic methods. Structural elucidation was based on NMR and MS data, in comparison with those reported in the literature. <strong>Results: </strong>The isolated compounds from ethyl acetate and methanol extracts of <em>L. staurophyllum </em>were identified as nonanal (1), stigmasterol acetate (2), beta-sitosterol (3), quercetin 3-O-glucoside (4) and quercetin 3 &ndash; O - rhamnoglucoside (5) by comparison of their NMR spectral data with those reported in the literature. <strong>Conclusion:</strong> Ethyl acetate and methanol extracts of <em>L. staurophyllum</em> contain various flavonol glycosides and sterols as the main components. Pelargonic aldehyde (nonanal), a growth promoting factor in plant cells, is found to be occurred in this species and might be a cause of anti -diarrhea activity.</div> Lomatopodium staurophyllum Lomatopodium staurophyllum, Apiaceae, Nonanal, Stigmasterol acetate, Quercetin 3 -O-glucoside, Quercetin 3 – O - rhamnoglucoside 43 48 http://jmp.ir/browse.php?a_code=A-10-161-1&slc_lang=fa&sid=1 AR Gohari AR Gohari 100319475328460037484 100319475328460037484 No Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences S Saeidnia S Saeidnia saeidnia_s@tums.ac.ir 100319475328460037485 100319475328460037485 Yes Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences M Malmir M Malmir 100319475328460037486 100319475328460037486 No Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences M Yazdanpanah M Yazdanpanah 100319475328460037487 100319475328460037487 No Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences Y Ajani Y Ajani 100319475328460037488 100319475328460037488 No Department of Pharmacognosy, Institute of Medicinal Plants, ACECR Department of Pharmacognosy, Institute of Medicinal Plants, ACECR