en Passionflower and Sage for Mental Health داروسازی سنتی و طب سنتی Traditional Pharmacy & Traditional Medicine پژوهشی Research <div dir="ltr" style="text-align: justify;">Herbal medicines include a range of pharmacologically active compounds: in some cases it is not well understood which ingredients are important for a therapeutic effect. The supporters of herbal medicine believe that isolated ingredients in the majority of cases have weaker clinical effects than whole plant extract, a claim that would obviously require proof in each case. Generalizations about the efficacy of herbal medicines are clearly not possible. Each one needs systematic research including a variety of animal studies and also randomized clinical trials. In this review we focus on <em>Passiflora incarnata</em> and <em>Salvia officinalis</em>.</div> <div style="text-align: justify;">Herbal medicines include a range of pharmacologically active compounds: in some cases it is not well understood which ingredients are important for a therapeutic effect. The supporters of herbal medicine believe that isolated ingredients in the majority of cases have weaker clinical effects than whole plant extract, a claim that would obviously require proof in each case. Generalizations about the efficacy of herbal medicines are clearly not possible. Each one needs systematic research including a variety of animal studies and also randomized clinical trials. In this review we focus on <em>Passiflora incarnata</em> and <em>Salvia officinalis</em>.</div> Evidence based Medicine, Herbal Medicine, Mental health, Passiflora incarnate, Salvia officinalis, Evidence based Medicine, Herbal Medicine, Mental health, Passiflora incarnate, Salvia officinalis 1 6 http://jmp.ir/browse.php?a_code=A-10-34-4&slc_lang=en&sid=1 R Hajiaghaee R Hajiaghaee 100319475328460042131 100319475328460042131 No Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR Pharmacognosy & Pharmaceutics Department of Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR S Akhondzadeh S Akhondzadeh s.akhond@neda.net 100319475328460042132 100319475328460042132 Yes Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences