%0 Journal Article %A Vanaky, Behnaz %A Shakeri, Nader %A Nikbakht, Hojat Allah %A Farzanegi, Parvin %T The effect of 6 weeks swimming and consumption of Zingiber officinale Roscoe extract on some inflammatory and anti-inflammatory factors in heart tissue of mice induced by breast cancer %J Journal of Medicinal Plants %V 17 %N 68 %U http://jmp.ir/article-1-1771-en.html %R %D 2018 %K Breast cancer, Ginger supplemen, Heart tissue, Inflammation, Swimming, %X Back ground: Heart disease is one of the side effects of breast cancer. Physical activity and herbs are effective in reducing the inflammatory factors of the heart tissue. Objective: The purpose of this study was to evaluate the effect of 6 weeks of swimming and ginger on some inflammatory factors of the heart tissue of mice induced by breast cancer. Methods: 60 female Balb C-female (6-8 weeks old) and (150-250 g weight) after induction of breast cancer (surgical technique) and familiarity with the environment were randomly divided into 6 groups: healthy control, control Cancer, Cancer-Swim, Cancer-Supplement, Cancer-Saline-Supplement and Cancer-Saline. Swimming and swimming-Supplement groups swam for 6 weeks, five days a week and 60 minutes a day. Supplements and supplements-swimming groups were injected 6 days a day with ginger extract (20 mg / kg) and saline (sodium chloride 0.9%). After intervention, alpha-Tumor necrosis levels (TNFα) and Interleukin10 (IL10) were measured by ELISA and specialized kits. One-way analysis of variance was used to analyze the data (P <0.05). Results: The results showed that induction of cancer was associated with an increase in TNFα and a decrease in IL10. Six weeks of swimming, supplementation and combined intervention reversed these changes. But there is no significant difference between these three independent variables. Conclusion: Swimming, supplementation of ginger and their combination may be effective in modulating inflammatory and anti-inflammatory factors in the heart tissue of breast cancer patients. %> http://jmp.ir/article-1-1771-en.pdf %P 32-40 %& 32 %! %9 Research %L A-10-1609-1 %+ Department of Physical Education and Sport Sciences, Sciences and Research Branch, Islamic Azad University, Tehran, Iran %G eng %@ 2717-204X %[ 2018