RT - Journal Article T1 - Anti-emtic effect of Trachyspermum ammi L. fruit extracts in young chickens JF - jmpir YR - 2004 JO - jmpir VO - 3 IS - 9 UR - http://jmp.ir/article-1-751-en.html SP - 15 EP - 22 K1 - Trachyspermum ammi fruit K1 - Anti-emetic K1 - Young chickens K1 - Copper sulfate K1 - Ipecac AB - The anti-emetic effect of the aqueous and ethanolic extracts of Trachyspermum ammi fruit was studied in young chickens. Emesis was induced in the chickens using copper sulfate (60 mg/kg, orally) and ipecac (600 mg/kg, orally). The LD50 values of the aqueous and ethanolic extracts (i.p.) were 2753 mg/kg and 747 mg/kg in the chickens, respectively. The aqueous extract (800-2000 mg/kg, i.p.) and ethanolic extract (40-100 mg/kg, i.p.) significantly prevented the emesis induced by copper sulfate and ipecac. These results indicate that the extracts of T. ammi fruit extracts have an anti-emetic activity in young chickens with peripheral and central mechanisms. LA eng UL http://jmp.ir/article-1-751-en.html M3 ER -